BH3 Interacting Domain Death Agonist Protein

08/01/2010 - "Deficiency of Bid protein reduces sepsis-induced apoptosis and inflammation, while improving septic survival."
01/01/2014 - "Sitagliptin also decreased IL-1β and TNF-α levels, as well as, prevented the increase of BAX/Bcl-2 ratio, Bid protein levels, and TUNEL-positive cells which indicates protective effects against inflammation and proapoptotic state in the kidney of diabetic rats, respectively. "
03/01/2016 - "In NASH mice, after 3weeks of treatment, BID protein was reduced to 10% and this was associated with an improvement in liver fibrosis and inflammation associated with a marked reduction in TUNEL positive cells, caspase 3 activation, and a reduction in mitochondrial BAX and BAK. "

03/01/2016 - "In NASH mice, after 3weeks of treatment, BID protein was reduced to 10% and this was associated with an improvement in liver fibrosis and inflammation associated with a marked reduction in TUNEL positive cells, caspase 3 activation, and a reduction in mitochondrial BAX and BAK. "

11/01/2020 - "Indeed, the sequential CTSC silencing and curcumin treatment also significantly curtailed tumor volume as well as ameliorated cytosolic cyt c and tBID protein levels in tumor tissues compared to those in control and individual treatments of CTSC targeting and on curcumin treatment in nude mice xenografts. "
10/18/2014 - "Controlled delivery of BID protein fused with TAT peptide sensitizes cancer cells to apoptosis."
09/01/2013 - "Moreover, Mith also inhibited the phosphorylation of mTOR on serine 2448 and Mcl-1, and increased tBid protein in prostate tumors in athymic nude mice bearing DU145 cells as xenografts. "
05/01/2015 - "Overexpression of the BH3-interacting domain death agonist (BID) protein sensitizes certain cancer cell lines to apoptosis induced by anticancer agents, particularly by those acting through death receptors (e.g. "
11/07/2014 - "Gli1 protein regulates the S-phase checkpoint in tumor cells via Bid protein, and its inhibition sensitizes to DNA topoisomerase 1 inhibitors."

01/01/2020 - "Upon 808 nm light excitation, the lysosomal cellular uptake initialized by poly(ethylenimine)-modified nanoheaters promoted mitochondria apoptosis through the activation of Bid protein, whereas the cell surface nanoheaters anchored via metabolic glycol biosynthesis triggered necrosis by direct perturbation of the membrane structure. "
02/01/2015 - "In summary, caspase inhibition decreases caspase-1, IL-1α, and IL-1β but not NLRP3 or BID protein and protects against necrosis in cisplatin-treated freshly isolated PTs."
11/11/2014 - "Tumour necrosis factor-related apoptosis-inducing ligand sensitivity was associated with high caspase-8 and Bid protein levels, and TRAIL-sensitive cell lines were killed via the type II extrinsic apoptotic pathway. "

01/01/2006 - "p53 protein or BID protein select the route to either apoptosis (programmed cell death) or to cell cycle arrest opposing carcinogenesis after DNA damage by ROS."