Small Heat-Shock Proteins

10/01/2012 - "Small heat shock proteins in cancer therapy and prognosis."
03/01/2006 - "Recently, the role of small heat shock proteins (HSPs) has been widely recognized in cancer research. "
09/04/1997 - "We have developed a novel system for examining the possible contribution of small heat shock proteins (hsp) to tumor growth. "
06/01/2015 - "HSPB1 belongs to the family of small heat shock proteins (sHSP) that have importance in protection against unfolded protein stress, in cancer cells for escaping drug toxicity stress and in neurons for suppression of protein aggregates. "
01/01/2014 - "Human small heat shock proteins are molecular chaperones that regulate fundamental cellular processes in normal unstressed cells as well as in many cancer cells where they are over-expressed. "

01/01/2014 - "Previously we reported that a multivalent fusion protein vaccine (rBmHAT) composed of small heat shock proteins 12.6 (HSP12.6), abundant larval transcript-2 (ALT-2) and large extracellular domain of tetraspanin (TSP LEL) could confer >95% protection against the challenge infection with Brugia malayi infective larvae (L3) in mouse and gerbil models. "
01/01/2015 - "Small heat shock proteins (sHSPs) perform a fundamental role in protecting cells against a wide array of stresses but their biological function during viral infection remains unknown. "
06/01/2014 - "Small heat shock proteins (HSPs) have important roles in infection and immunity, especially between invertebrate vectors and mammalian hosts while initially performing their molecular chaperone activity. "
02/01/2015 - "Small heat-shock proteins (sHsps) are a diverse family of intra-cellular molecular chaperone proteins that play a critical role in mitigating and preventing protein aggregation under stress conditions such as elevated temperature, oxidation and infection. "

01/01/2010 - "Protein quality control in protection against systolic overload cardiomyopathy: the long term role of small heat shock proteins."

10/19/2012 - "Chaperone activity of small heat shock proteins underlies therapeutic efficacy in experimental autoimmune encephalomyelitis."

06/01/2015 - "HSPB1 belongs to the family of small heat shock proteins (sHSP) that have importance in protection against unfolded protein stress, in cancer cells for escaping drug toxicity stress and in neurons for suppression of protein aggregates. "