HSC70 Heat-Shock Proteins
A constitutively expressed subfamily of the HSP70 heat-shock proteins. They preferentially bind and release hydrophobic peptides by an ATP-dependent process and are involved in post-translational PROTEIN TRANSLOCATION.
Also Known As:
70 kDa Heat-Shock Cognate Protein; Clathrin Uncoating Protein; HSC73 Protein; 70 kDa Heat Shock Cognate Protein; HSC70 Heat Shock Proteins; Heat Shock Cognate 70 Protein; Heat-Shock Proteins, HSC70; Uncoating Protein, Clathrin; Heat-Shock Cognate 70 Protein; Hsc70 Protein
Networked: 19
relevant articles (0 outcomes,
3 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Caprioli, Joseph:
2 articles
(05/2003 - 01/2003)
|
2. | Ishii, Yoko:
2 articles
(05/2003 - 01/2003)
|
3. | Kwong, Jacky M K:
2 articles
(05/2003 - 01/2003)
|
4. | Acosta, Orlando:
1 article
(08/2021)
|
5. | Guerrero, Carlos:
1 article
(08/2021)
|
6. | Hernandez, Juan:
1 article
(08/2021)
|
7. | Perez, Claudia:
1 article
(08/2021)
|
8. | Rico, José:
1 article
(08/2021)
|
9. | Storey, Janet M:
1 article
(01/2019)
|
10. | Storey, Kenneth B:
1 article
(01/2019)
|
Related Diseases
1. | Glaucoma
|
2. | Hypoxia (Hypoxemia)
|
3. | Dehydration (Water Stress)
|
4. | Neoplasms (Cancer)
01/07/2010
- " Heat shock cognate 70 protein secretion as a new growth arrest signal for cancer cells." 03/01/2004
- " Tumors with weak (+) HSC70 protein staining were more frequent in the carriers of the polymorphic 1541-1542delGT allele than in the homozygotes of the major allele (20% vs. 6%, P=0.05 by Fisher's exact test). " 11/15/1993
- " 70 kDa heat shock cognate protein is a transformation-associated antigen and a possible target for the host's anti-tumor immunity." 08/01/2021
- " The results indicated that the rotavirus isolates studied were able to infect U937 cells by interacting with Hsp90, Hsp70, Hsp60, Hsp40, Hsc70, protein disulfide isomerase (PDI), and integrin β3, which are implicated in cellular proliferation, differentiation, and cancer development. "
|
5. | Parkinson Disease (Parkinson's Disease)
|
|
Related Drugs and Biologics
Related Therapies and Procedures