Betalains

05/01/2023 - "This review summarizes findings in the literature and highlights the therapeutic potential of betalains and their natural source as valid alternative for supplementation in obesity-related disorders treatment. "
05/01/2023 - "Betalains exert antioxidative, anti-inflammation, lipid lowering, antidiabetic and anti-obesity effects. "
01/01/2020 - "Betalains, carotenoids, phycocyanins, and anthocyanins are major food colorants used in the food industry that have documented biological effects, particularly in the prevention and management of chronic diseases such as diabetes, obesity, and cardiovascular disease. "
08/01/2020 - "Recent modern studies have shown a variety of health benefits for red beetroot and its active compounds betalains (also betanin) such as antioxidative, anti-inflammation, anticancer, blood pressure and lipid lowering, also antidiabetic and anti-obesity effects. "
11/15/2021 - "The studied species are good sources of nutrients and phytochemicals of biological interest, such as phenolic compounds, carotenoids, betalains, phytosterols, tocopherols, etc. They also have shown great potential in preventing some diseases, including diabetes, obesity, cancer, and others. "

12/01/2021 - "However, studies on the protective effect of betalain against heart failure have not reported yet. "
12/01/2021 - "Betalain exerts cardioprotective and anti-inflammatory effects against the experimental model of heart failure."
12/01/2021 - "The animals were randomly assigned into four groups such as sham-control, ISO-induced heart failure, betalain pretreated before ISO induction (50 mg/kg/day), and betalain drug control group were maintained for 6 weeks. "
12/01/2021 - "While betalain pre-treated rats prevented the cardiac failure significantly (p < 0.01) with improved anti-oxidant enzymes, abrogated the inflammatory signals with restored matrix proteins, cardiac biomarker genes, and attenuated miR-423 and miR-27 compared to heart failure rats. "

07/14/2020 - "Thus, the results of the present study demonstrate that the use of betalain on ocular cells can prevent the progression of the disease that can be a suggestive therapeutic for controlling glaucoma like conditions."
07/14/2020 - "The present research aimed at evaluating the protective role of betalain on the in vitro glaucoma model using PC12 neuronal cells. "
07/14/2020 - "Betalain exerts a protective effect against glaucoma is majorly through the association of inflammatory cytokines."
07/14/2020 - "The cultured neuronal cells in a customized pressurized chamber were analyzed for the onset of glutathione, myeloperoxidase (MPO), cathepsin, expression of inflammatory enzymes such as cyclooxygenase (COX-1), lipoxygenase (5- LOX), sPLA2 caveolin-1, glaucoma markers and other inflammatory cytokines in the presence and absence of betalain. "

01/01/2022 - "This implies that regular dragon fruit consumption may have a meaningful impact on cardiovascular disease risk likely due to the high betalain content. "
12/11/2019 - "Effects of betalains on atherogenic risk factors in patients with atherosclerotic cardiovascular disease."
01/01/2020 - "Betalains, carotenoids, phycocyanins, and anthocyanins are major food colorants used in the food industry that have documented biological effects, particularly in the prevention and management of chronic diseases such as diabetes, obesity, and cardiovascular disease. "

01/01/2022 - "Therefore, we conclude that the aqueous extract of the xoconostle fruit where betalains are present may be useful for the treatment of diabetes mellitus."