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Octamer Transcription Factors

A family of POU domain factors that bind the octamer motif ATTTGCAT in enhancer and PROMOTER REGIONS to regulate GENE EXPRESSION.

Also Known As:

Oct Proteins; Transcription Factors, Octamer

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Badeaux, Mark: 1 article (01/2017)
2.	Garkavtsev, Igor: 1 article (01/2017)
3.	Gupta, Nisha: 1 article (01/2017)
4.	Jain, Rakesh K: 1 article (01/2017)
5.	Liu, Yiqian: 1 article (01/2017)
6.	Munn, Lance L: 1 article (01/2017)
7.	Naxerova, Kamila: 1 article (01/2017)
8.	Sgroi, Dennis: 1 article (01/2017)
9.	Alfieri, Roberta: 1 article (12/2014)
10.	Ampollini, Luca: 1 article (12/2014)

Related Diseases

1.	Neuroblastoma 01/01/1994 - "Previously, we showed that N-Oct proteins are differentially expressed by human neuroblastoma and glioblastoma cell lines in vitro. " 06/01/2001 - "One of these was localized to an AT-rich 42-bp sequence shown by others to bind Oct proteins in neuroblastoma cells, while the other corresponded to a composite AP-1/ets element. "
2.	Carcinogenesis 12/01/2014 - "Interestingly, nuclear transcription factors octamer-binding transcription factor 3/4 and sex determining region Y-box 2 involved in stemness, thyroid transcription factor 1 in bronchoalveolar commitment, and ETS1 in carcinogenesis, were expressed in hLc-MCs isolated from NSCLC. "
3.	Pathologic Processes 01/01/2013 - "In this review, I will report both the genomic structure and major functions of individual Oct proteins in physiological and pathological processes."
4.	Neoplasms (Cancer) 01/01/2013 - "The aberrant expression and null function of Oct proteins have also been linked to various diseases, including deafness, diabetes and cancer. "
5.	Lymphoma (Lymphomas) 01/01/1994 - "Thus, metastatic carcinoma and lymphoma expressed a non-nervous system phenotype of Oct proteins."

Related Drugs and Biologics

1.	Transcription Factor 3
2.	Messenger RNA (mRNA)
3.	Elements
4.	Carrier Proteins (Binding Protein)
5.	Thyroid Nuclear Factor 1
6.	squamous cell carcinoma-related antigen