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D-Aspartate Oxidase

An FAD-dependent peroxisomal flavoenzyme, this catalyzes the oxidative deamination of D-ASPARTATE to OXALOACETATE and AMMONIA using oxygen as electron acceptor.
Also Known As:
Aspartic Oxidase; D-aspartic Oxidase; D Aspartate Oxidase; D aspartic Oxidase; Oxidase, Aspartic; Oxidase, D-Aspartate; Oxidase, D-aspartic
Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Errico, Francesco: 2 articles (01/2017 - 12/2011)
2. Napolitano, Francesco: 2 articles (01/2017 - 12/2011)
3. Usiello, Alessandro: 2 articles (01/2017 - 12/2011)
4. Bertolino, Alessandro: 1 article (01/2017)
5. Carella, Massimo: 1 article (01/2017)
6. Chiariotti, Lorenzo: 1 article (01/2017)
7. Copetti, Massimiliano: 1 article (01/2017)
8. Florio, Ermanno: 1 article (01/2017)
9. Keller, Simona: 1 article (01/2017)
10. Nuzzo, Tommaso: 1 article (01/2017)

Related Diseases

1. Dyskinesias (Dyskinesia)
2. Schizophrenia (Dementia Praecox)
3. Zellweger Syndrome (Zellweger's Syndrome)
4. Prader-Willi Syndrome (Syndrome, Prader-Willi)
03/01/2010 - "Detailed gene expression analysis showed a variety of genes whose upregulation (platelet-derived growth factor receptor alpha polypeptide, solute carrier family 39 member 14, solute carrier family 2 member 3, pleiotrophin, trophinin, pleckstrin and Sec7 domain containing 3, enolase 2, biglycan, SH3 and cysteine-rich domain, matrix metalloproteinases 16) and whose downregulation (tissue inhibitor of metalloproteinase 4, hairy/enhancer of split related with YRPW motif 2, protein tyrosine phosphatase receptor-type Z polypeptide 1, SH3 domain GRB2-like 2, microtubule-associated protein 7, potassium voltage-gated channel shaker-related subfamily member 1, RUN and FYVE domain containing 3, Sin3A-associated protein 18 kDa, proline-rich 4, calcium/calmodulin-dependent protein kinase ID, myeloid/lymphoid or mixed-lineage leukemia translocated to 3, insulin-like growth factor binding protein 5, nucleoside diphosphate-linked moiety X-type motif 9, NudC domain containing 3, imprinted in Prader-Willi syndrome, TAF6-like RNA polymerase II p300/CBP-associated factor 65 kDa, WD repeat and SOCS box-containing 2, adenosine diphosphate ribosylation factor 3, KRR1, proliferation-associated 2G4; CD36, complement component (3b/4b) receptor 1, solute carrier family 4 sodium bicarbonate cotransporter member 4, lipoprotein lipase (LPL), GATA binding protein 3, LPL, glutathione peroxidase 3, D: -aspartate oxidase, apolipoprotein E, sphingomyelin phosphodiesterase acid-like 3A) were associated with poor clinical outcome in terms of development of metastatic or recurrent disease. "
5. Intellectual Disability (Idiocy)

Related Drugs and Biologics

1. Enzymes
2. Biglycan
3. Class 5 Receptor-Like Protein Tyrosine Phosphatases
4. Sarcosine Oxidase
5. Sodium-Bicarbonate Symporters
6. D-Aspartic Acid (D Aspartate)
7. Matrix Metalloproteinases (MMPs)
8. Insulin-Like Growth Factor Binding Protein 5
9. Calcium-Calmodulin-Dependent Protein Kinases
10. Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)