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Core Binding Factors (Core-Binding Factor)

Heterodimeric transcription factors containing a DNA-binding alpha subunits, (CORE BINDING FACTOR ALPHA SUBUNITS), along with a non-DNA-binding beta subunits, CORE BINDING FACTOR BETA SUBUNIT. Core Binding Factor regulates GENETIC TRANSCRIPTION of a variety of GENES involved primarily in CELL DIFFERENTIATION and CELL CYCLE progression.
Also Known As:
Core-Binding Factor; PEBP2 Transcription Factor; Polyomavirus Enhancer Binding Protein 2; Binding Factors, Core; Core Binding Factor; Factors, Core Binding; Transcription Factor, PEBP2
Networked: 400 relevant articles (27 outcomes, 35 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Borthakur, Gautam: 21 articles (01/2022 - 12/2008)
2. Ravandi, Farhad: 20 articles (01/2022 - 12/2008)
3. Garcia-Manero, Guillermo: 12 articles (01/2022 - 12/2008)
4. Kantarjian, Hagop: 11 articles (01/2021 - 12/2008)
5. Marcucci, Guido: 10 articles (01/2021 - 09/2003)
6. Paschka, Peter: 10 articles (12/2020 - 08/2006)
7. Boissel, Nicolas: 9 articles (01/2022 - 03/2009)
8. Bloomfield, Clara D: 9 articles (01/2021 - 09/2003)
9. Döhner, Konstanze: 9 articles (12/2020 - 08/2007)
10. Beghini, Alessandro: 9 articles (12/2019 - 01/2002)

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1. Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
2. Leukemia
3. Hypoxia (Hypoxemia)
4. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
5. Myelodysplastic Syndromes (Myelodysplastic Syndrome)

Related Drugs and Biologics

1. Cytarabine (Cytosar-U)
2. Dasatinib (BMS 354825)
3. Gemtuzumab (Mylotarg)
4. fludarabine
5. Transcription Factors (Transcription Factor)
6. Osteocalcin
7. Oxygen (Dioxygen)
8. Granulocyte Colony-Stimulating Factor (G-CSF)
9. Daunorubicin (Cerubidine)
10. venetoclax

Related Therapies and Procedures

1. Therapeutics
2. Induction Chemotherapy
3. Stem Cell Transplantation
4. Drug Therapy (Chemotherapy)
5. Cell Transplantation