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gamma-Butyrobetaine Dioxygenase

An enzyme that catalyzes the HYDROXYLATION of gamma-butyrobetaine to L-CARNITINE. It is the last enzyme in the biosynthetic pathway of L-CARNITINE and is dependent on alpha-ketoglutarate; IRON; ASCORBIC ACID; and OXYGEN.
Also Known As:
4-Trimethylaminobutyrate, 2-Oxoglutarate Oxygen Oxidoreductase (3-Hydroxylating); Butyrobetaine Hydroxylase; Trimethylaminobutyrate Hydroxylase; gamma-Butyrobetaine Hydroxylase; gamma-Butyrobetaine, 2-Oxoglutarate Dioxygenase; gamma-Butyrobetaine,2-Oxoglutarate Dioxygenase; 2-Oxoglutarate Dioxygenase gamma-Butyrobetaine; Dioxygenase gamma-Butyrobetaine, 2-Oxoglutarate; Dioxygenase, gamma-Butyrobetaine; Dioxygenase, gamma-Butyrobetaine,2-Oxoglutarate; Hydroxylase, Butyrobetaine; Hydroxylase, Trimethylaminobutyrate; Hydroxylase, gamma-Butyrobetaine; gamma Butyrobetaine Dioxygenase; gamma Butyrobetaine Hydroxylase; gamma Butyrobetaine, 2 Oxoglutarate Dioxygenase; gamma Butyrobetaine,2 Oxoglutarate Dioxygenase
Networked: 14 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Hayashi, Y: 3 articles (11/2000 - 05/2000)
2. Kirimoto, T: 3 articles (11/2000 - 05/2000)
3. Matsuura, N: 3 articles (11/2000 - 05/2000)
4. Miyake, H: 3 articles (11/2000 - 05/2000)
5. Tajima, K: 3 articles (11/2000 - 05/2000)
6. Chen, Y Eugene: 2 articles (01/2022 - 01/2020)
7. Cheng, Si: 2 articles (01/2022 - 01/2020)
8. Garcia-Barrio, Minerva T: 2 articles (01/2022 - 01/2020)
9. Ji, Liang: 2 articles (01/2022 - 01/2020)
10. Meng, Xiangbao: 2 articles (01/2022 - 01/2020)

Related Diseases

1. Myocardial Infarction
2. Carcinogenesis
3. Neoplasms (Cancer)
4. Heart Failure
5. Mitochondrial Diseases (Mitochondrial Disease)

Related Drugs and Biologics

1. Carnitine (L-Carnitine)
2. 3-(2,2,2-trimethylhydrazine)propionate
3. Enzymes
4. N,N,N-trimethyl-5-aminovaleric acid
5. Small Interfering RNA (siRNA)
6. Antisense RNA (Anti-Sense RNA)
7. Biomarkers (Surrogate Marker)
8. Trehalose
9. Thiosulfate Sulfurtransferase (Rhodanese)
10. Sphingolipids