D-Xylulose Reductase

An enzyme that plays a role in the PENTOSES and GLUCURONATES interconversion pathway by catalyzing the oxidation of XYLITOL to D-xylulose. This enzyme has been found to be specific for NAD+.

Also Known As:

NAD-Dependent Xylitol Dehydrogenase; Xylitol Dehydrogenase; D Xylulose Reductase; Dehydrogenase, NAD-Dependent Xylitol; Dehydrogenase, Xylitol; NAD Dependent Xylitol Dehydrogenase; Reductase, D-Xylulose; Xylitol Dehydrogenase, NAD-Dependent; xylitol NAD 2-oxidoreductase (D-xylulose-forming)

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - Alcohol Oxidoreductases: 56
      - Carbohydrate Dehydrogenases
        Sugar Alcohol Dehydrogenases
        D-Xylulose Reductase: 2
      - NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases
        D-Xylulose Reductase: 2

Experts

1.	Bolotnikova, O I: 1 article (07/2003)
2.	Ginak, A I: 1 article (07/2003)
3.	Iablochkova, E N: 1 article (07/2003)
4.	Mikhaĭlova, N P: 1 article (07/2003)
5.	Nemova, N N: 1 article (07/2003)

Related Diseases

1.	Neoplasms (Cancer) 08/01/1981 - "The activity ofa nicotinamide adenine dinucleotide-dependent polyol dehydrogenase in various hepatomas ranged from nondetectable to 30 nmol/min/mg protein, with the lower activities in FB56 and AS-30D tumors at 0 and 0.22 nmol/min/mg, respectively; while nicotinamide adenine dinucleotide phosphate-dependent xylitol dehydrogenase activities ranged from 0 to FB56 to 3.31 nmol/min/mg protein in liver regenerated for 1 week. "
2.	Hepatocellular Carcinoma (Hepatoma) 08/01/1981 - "The activity ofa nicotinamide adenine dinucleotide-dependent polyol dehydrogenase in various hepatomas ranged from nondetectable to 30 nmol/min/mg protein, with the lower activities in FB56 and AS-30D tumors at 0 and 0.22 nmol/min/mg, respectively; while nicotinamide adenine dinucleotide phosphate-dependent xylitol dehydrogenase activities ranged from 0 to FB56 to 3.31 nmol/min/mg protein in liver regenerated for 1 week. "
3.	Torulopsis 07/01/2003 - "The activity and the cofactor specificity of xylose reductase and xylitol dehydrogenase were studied in extracts of yeasts from the genera Candida, Kluyveromyces, Pachysolen, Pichia, and Torulopsis grown under microaerobic conditions. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	NADP (NADPH)
3.	NAD (NADH)
4.	L-Iditol 2-Dehydrogenase (L Iditol 2 Dehydrogenase)
5.	Aldehyde Reductase (Aldose Reductase)