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Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)

A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is an extrahepatic enzyme that plays a role in metabolism as the first and rate limiting enzyme in the kynurenine pathway of TRYPTOPHAN catabolism.
Also Known As:
Indoleamine 2,3 Dioxygenase; IDO Dioxygenase; Indolamine-2,3-Dioxygenase; Indoleamine 2,3-Dioxygenase; Indoleamine-Oxygen 2,3-Oxidoreductase (Decyclizing); Dioxygenase, IDO; Indolamine 2,3 Dioxygenase
Networked: 1311 relevant articles (35 outcomes, 108 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Mellor, Andrew L: 28 articles (01/2021 - 04/2002)
2. Munn, David H: 27 articles (10/2021 - 04/2002)
3. Saito, Kuniaki: 23 articles (03/2021 - 02/2008)
4. Prendergast, George C: 21 articles (10/2020 - 03/2005)
5. Takikawa, Osamu: 21 articles (08/2014 - 01/2003)
6. Fuchs, Dietmar: 19 articles (01/2020 - 10/2004)
7. Muller, Alexander J: 18 articles (01/2018 - 03/2005)
8. Puccetti, Paolo: 16 articles (01/2020 - 03/2005)
9. Sakurai, Kenichi: 16 articles (10/2018 - 08/2002)
10. Enomoto, Katsuhisa: 15 articles (10/2018 - 10/2004)

Related Diseases

1. Neoplasms (Cancer)
2. Colitis
3. Melanoma (Melanoma, Malignant)
4. Neoplasm Metastasis (Metastasis)
5. Bites and Stings (Sting)

Related Drugs and Biologics

1. Enzymes
2. Tryptophan (L-Tryptophan)
3. Tryptophan Oxygenase (Tryptophan 2,3 Dioxygenase)
4. Immune Checkpoint Inhibitors
5. Kynurenine
6. Ligands
7. B7-H1 Antigen
8. Immunoglobulins (Immunoglobulin)
9. Vaccines
10. Poly I-C

Related Therapies and Procedures

1. Immunotherapy
2. Therapeutics
3. Drug Therapy (Chemotherapy)
4. Radiotherapy
5. Neoadjuvant Therapy