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Vesicular Acetylcholine Transport Proteins (Vesicular Acetylcholine Transporter)

Vesicular amine transporter proteins that transport the neurotransmitter ACETYLCHOLINE into small SECRETORY VESICLES. Proteins of this family contain 12 transmembrane domains and exchange vesicular PROTONS for cytoplasmic acetylcholine.
Also Known As:
Vesicular Acetylcholine Transporter; VAChT Proteins; Acetylcholine Transporter, Vesicular; Transporter, Vesicular Acetylcholine; Transporters, Vesicular Acetylcholine; Vesicular Acetylcholine Transporters; Acetylcholine Transporters, Vesicular; Vesicular Acetylcholine Transporter Proteins
Networked: 96 relevant articles (0 outcomes, 12 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Parsons, Stanley M: 7 articles (02/2020 - 05/2006)
2. Liu, Hui: 6 articles (11/2021 - 04/2015)
3. Perlmutter, Joel S: 6 articles (11/2021 - 04/2015)
4. Tu, Zhude: 6 articles (11/2021 - 04/2015)
5. Guilloteau, Denis: 5 articles (11/2012 - 05/2006)
6. Koeppe, Robert A: 4 articles (01/2022 - 07/2017)
7. Allard, Michèle: 4 articles (12/2021 - 11/2012)
8. Lamare, Frédéric: 4 articles (12/2021 - 01/2013)
9. Prado, Marco A M: 4 articles (01/2021 - 05/2008)
10. Kaneshige, Kota: 4 articles (11/2018 - 04/2015)

Related Diseases

1. Alzheimer Disease (Alzheimer's Disease)
2. Ganglion Cysts (Ganglion)
01/28/2009 - "In controls, most cardiac ganglion neurons expressed vesicular acetylcholine transporter, frequently colocalized with vesicular monoamine transporter, but lacked catecholamine histofluorescence. "
11/01/2001 - "To determine the expression patterns of the vesicular acetylcholine transporter (VAChT), tyrosine hydroxylase (TH) and neuronal nitric oxide synthase (nNOS) in the pterygopalatine ganglion (PPG) and the exorbital lacrimal gland of normal mice. "
10/01/2023 - "Human choroid and eye-related cranial ganglia (superior cervical ganglion- SCG, ciliary ganglion-CIL, pterygopalatine ganglion-PPG, trigeminal ganglion-TRI) were prepared for immunohistochemistry against UCN, protein-gene product 9.5 (PGP9.5), substance P (SP), tyrosine hydroxylase (TH) and vesicular acetylcholine transporter (VAChT). "
12/01/2015 - "We collected the L4 sympathetic trunk ganglion (STG), that our preliminary studies proved to contain the highest number (575.5 ± 152.93; mean ± S.E.M., n = 4) of FB+ sympathetic neurons projecting to CM. About half of the CM projecting neurons of this ganglion were catecholaminergic and showed the colocalization of Tyrosine Hydroxylase (TH) with Neuropeptide Y (NPY), Leu-Enkephaline (LENK), Vasoactive Intestinal Polypeptide (VIP), Calcitonine Gene Related Peptide (CGRP), Substance P (SP), neuronal Nitric Oxyde Sinthase (n-NOS), and Vesicular Acetylcholine Transporter (VAChT). "
02/24/2021 - "Immunohistochemistry revealed significant changes in the chemical coding of FB+ cells only in the right ganglion: decreased expression of dopamine-B-hydroxylase (DBH)/tyrosine hydroxylase (TH) and up-regulation of the vesicular acetylcholine transporter (VAChT)/choline acetyltransferase (ChAT), galanin (GAL), vasoactive intestinal polypeptide (VIP) and brain nitric oxide synthase (bNOS). "
3. Dementia (Dementias)
4. Cognitive Dysfunction
5. Parkinson Disease (Parkinson's Disease)

Related Drugs and Biologics

1. Cholinergic Agents (Cholinergics)
2. Vasoactive Intestinal Peptide (VIP (Vasoactive Intestinal Peptide))
3. Biomarkers (Surrogate Marker)
4. Synaptophysin
5. Choline O-Acetyltransferase (Choline Acetyltransferase)
6. Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)
7. Proteins (Proteins, Gene)
8. Substance P
9. fluoroethoxy-benzovesamicol
10. Messenger RNA (mRNA)

Related Therapies and Procedures

1. Electroacupuncture
2. Ligation