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Vesicular Monoamine Transport Proteins (Vesicular Monoamine Transporter)

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A family of vesicular amine transporter proteins that catalyze the transport and storage of CATECHOLAMINES and indolamines into SECRETORY VESICLES.
Also Known As:
Vesicular Monoamine Transporter; Vesicular Monoamine Transporter 1; Vesicular Monoamine Transporter 2; Chromaffin Granule Amine Transporter; Monoamine Vesicular Transport Proteins; Monoamine Vesicular Transporter; VMAT-1 Vesicular Monoamine Transporter; VMAT2 Vesicular Monoamine Transporter; Monoamine Transporter, Vesicular; VMAT 1 Vesicular Monoamine Transporter; Vesicular Monoamine Transporters; Vesicular Transporter, Monoamine; Monoamine Transporters, Vesicular; Vesicular Monoamine Transporter Proteins
Networked: 121 relevant articles (3 outcomes, 17 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Frey, Kirk A: 8 articles (05/2013 - 06/2002)
2. Albin, Roger L: 7 articles (05/2013 - 06/2002)
3. Koeppe, Robert A: 6 articles (05/2013 - 09/2006)
4. Weizman, Abraham: 6 articles (08/2011 - 08/2002)
5. Rehavi, Moshe: 6 articles (08/2011 - 08/2002)
6. Kung, Hank F: 5 articles (06/2014 - 08/2006)
7. Bohnen, Nicolaas I: 5 articles (05/2013 - 09/2006)
8. Lohoff, Falk W: 4 articles (11/2013 - 12/2006)
9. Müller, Martijn L T M: 4 articles (05/2013 - 06/2010)
10. Tsolakis, Apostolos V: 3 articles (12/2015 - 04/2008)

Related Diseases

1. Pheochromocytoma
11/17/1997 - "Molecular cloning has recently demonstrated that the vesicular transporters for monoamines and ACh show strong sequence similarity, and studies of the vesicular monoamine transporters (VMATs) indicate preferential localization to large dense core vesicles (LDCVs) rather than synaptic-like microvesicles (SLMVs) in rat pheochromocytoma PC12 cells. "
05/14/1996 - "A second isoform of the human vesicular monoamine transporter (hVMAT) has been cloned from a pheochromocytoma cDNA library. "
06/01/2010 - "6-18F-fluoro-L-dihydroxyphenylalanine positron emission tomography is superior to 123I-metaiodobenzyl-guanidine scintigraphy in the detection of extraadrenal and hereditary pheochromocytomas and paragangliomas: correlation with vesicular monoamine transporter expression."
08/01/2006 - "The aims of this study were to investigate the quantitative expression of vesicular monoamine transporters (VMAT 1, 2) and all five SSTRs in malignant pheochromocytoma/paraganglioma (PC/PG) to evaluate the possibilities for tumor-specific radionuclide therapy. "
02/01/2012 - "To evaluate the usefulness of [(18)F]-6-fluorodopamine ([(18)F]-DA) and [(18)F]-L-6-fluoro-3,4-dihydroxyphenylalanine ([(18)F]-DOPA) positron emission tomography (PET) in the detection of subcutaneous (s.c.) and metastatic pheochromocytoma in mice; to assess the expression of the norepinephrine transporter (NET) and vesicular monoamine transporters 1 and 2 (VMAT1 and VMAT2), all important for [(18)F]-DA and [(18)F]-DOPA uptake. "
2. Schizophrenia (Dementia Praecox)
3. Paraganglioma (Paragangliomas)
4. Substance-Related Disorders (Drug Abuse)
5. Hyperkinesis

Related Drugs and Biologics

1. Oxidoreductases
2. dihydrotetrabenazine
3. Tetrabenazine (Nitoman)
4. Dopamine (Intropin)
5. Messenger RNA (mRNA)
6. Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)
7. Dopa Decarboxylase
8. Histidine Decarboxylase
9. Cholecystokinin B Receptor
10. Ionomycin

Related Therapies and Procedures

1. Prostatectomy (Retropubic Prostatectomy)