A family of plasma membrane neurotransmitter transporter proteins that couple the uptake of GLUTAMATE with the import of SODIUM ions and PROTONS and the export of POTASSIUM ions. In the CENTRAL NERVOUS SYSTEM they regulate neurotransmission through synaptic reuptake of the excitatory neurotransmitter glutamate. Outside the central nervous system they function as signal mediators and regulators of glutamate metabolism.
Also Known As:
EAAT Proteins; Excitatory Amino Acid Transport Proteins; Excitatory Amino Acid Transporter Proteins; Glutamate Plasma Membrane Transporter Proteins; Sodium-Glutamate Cotransporter; Sodium-Glutamate Transporter; Cotransporter, Sodium-Glutamate; Glutamate-Specific Neurotransmitter Transporters; Neurotransmitter Transport Proteins, Glutamate Specific; Neurotransmitter Transporters, Glutamate Specific; Sodium Glutamate Cotransporter; Sodium Glutamate Transporter; Transporters, Glutamate-Specific Neurotransmitter; Neurotransmitter Transport Proteins, Glutamate-Specific; Neurotransmitter Transporters, Glutamate-Specific