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Urofollitropin (Bravelle)

Subscribe to New Research on Urofollitropin

A protein extract of human menopausal urine in which LUTEINIZING HORMONE has been partially or completely removed. Urofollitropin represents FOLLICLE STIMULATING HORMONE from the urine.

Also Known As:

Bravelle; Metrodin; Ferring Brand of Urofollitropin; Fertinex; Follitrin; Fustery Brand of Urofollitropin; Human FSH, Urinary; Metrodin HP; Metrodin High Purity; Neo Fertinorm; Serono Brand of Highly Purified Urofollitropin; Serono Brand of Urofollitropin; Follicle Stimulating Hormone, Human Urine; High Purity, Metrodin; Urinary Human FSH; Urofollitropin Ferring Brand; Urofollitropin Fustery Brand; Urofollitropin Serono Brand; Follicle-Stimulating Hormone, Human Urine

Networked: 23 relevant articles (1 outcomes, 0 trials/studies)

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Drug Context: Research Results

Experts

1.	Daya, Salim: 2 articles (01/2004 - 01/2002)
2.	Chen, Christopher: 1 article (09/2006)
3.	Kattera, Suresh: 1 article (09/2006)
4.	van der Veen, Fulco: 1 article (01/2005)
5.	van Wely, Madelon: 1 article (01/2005)
6.	Bayram, Neriman: 1 article (01/2005)
7.	Yding Andersen, Claus: 1 article (01/2005)
8.	Auray, Jean Paul: 1 article (01/2002)
9.	O'Brien, Mark: 1 article (01/2002)
10.	Wikland, Matts: 1 article (01/2002)

Related Diseases

1.	Ovarian Hyperstimulation Syndrome 02/01/1998 - "Measurement of estradiol may be less helpful in the monitoring of Metrodin-HP cycles, but the level reached on the day of hCG administration can still be used to predict, and hence avoid, ovarian hyperstimulation syndrome." 08/01/2000 - "Moderate to severe ovarian hyperstimulation syndrome occurred in 2.8 and 1.2% of Gonal-F and Metrodin HP patients respectively (not significant). " 01/01/2005 - "It remains unclear whether human menopausal gonadotropins have a higher risk of overstimulation and ovarian hyperstimulation syndrome compared to urofollitropin in women with polycystic ovary syndrome. " 02/01/1998 - "For Metrodin-HP versus Pergonal, the rates of egg retrieval (98 vs 94%), fertilization (89 vs 92%), clinical pregnancy (32.9 vs 23.4%), miscarriage (4.1 vs 4.5%), live birth (26 vs 18.5%), and ovarian hyperstimulation syndrome (5.5% vs 5.9%) were similar in both groups. "
2.	Infertility (Sterility) 01/01/2003 - " Pharmaceuticals has teamed up with the American Infertility Association and RESOLVE: the National Infertility Association to improve access to infertility treatment in the US, with the recent launch of the 'Bravelle' HEART (Helping Expand Access to Reproductive Therapy) Programme. " 01/01/2003 - "Ferring Pharmaceuticals has also submitted a New Drug Application for additional indications for Bravelle in infertility treatment, which is currently under review by the US FDA. " 01/01/2002 - "To compare the cost effectiveness of recombinant human FSH (Gonal-F; Serono, Inc., Randolph, MA) and urinary FSH (Fertinex; Serono, Inc.) for ovarian stimulation during IVF with or without intracytoplasmic sperm injection for the treatment of infertility. " 12/01/1993 - "From 1984 through 1991, chorionic gonadotropin, menotropins, and urofollitropin together accounted for no more than one third of the market share of the gonadotrophin class of drugs, whose primary indication is treatment of infertility. " 07/01/1996 - "A 38-year-old infertility patient who had experienced a whole-body rash with hives, tachycardia, fever, and other symptoms after urofollitropin administration, with confirmation of IgE-mediated sensitivity to urofollitropin by intradermal skin testing. "
3.	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 05/01/1997 - "Serum FSH levels in women with polycystic ovary syndrome during ovulation induction using down-regulation and urofollitropin." 10/01/1995 - "To compare changes in serum androgens in women with polycystic ovary syndrome (PCOS) during ovulation induction with low-dose versus conventional urofollitropin. " 01/01/2005 - "It remains unclear whether human menopausal gonadotropins have a higher risk of overstimulation and ovarian hyperstimulation syndrome compared to urofollitropin in women with polycystic ovary syndrome. " 02/01/1996 - "A consistent defect in follicle-stimulating hormone (FSH) secretion is seen in humans with Polycystic Ovarian Syndrome (PCOS); therefore, we evaluated whether Metrodin (a highly purified urinary FSH) administration concurrent with cyst induction or following cyst induction inhibits estrogen-induced cyst development and augments ovarian follicular growth in an established guinea pig model. "
4.	Ovarian Diseases (Ovarian Disease) 04/01/1989 - "Ovulation induction in polycystic ovarian disease by pure FSH (Metrodin). " 01/01/1983 - "Induction of ovulation and pregnancy with HU-FSH (Metrodin) in women with polycystic ovarian disease: summary of clinical experience." 05/01/1985 - "In patients with polycystic ovarian disease (PCOD) ovulation was induced with a combination of human menopausal gonadotropin (hMG) and human chorionic gonadotropin (hCG) or with urinary follicle-stimulating hormone (uFSH; Metrodin, Serono Laboratories, Inc., Randolph, MA) alone. "
5.	Anovulation 01/01/2004 - "In patients with WHO group II anovulation, protocols based on recombinant FSH are more effective than conventional protocols using urofollitropin. " 03/01/1998 - "As ovulation induction in women with clomifene-resistant WHO group II anovulation, follitropin alpha produces rates of ovulation, follicular development and pregnancy resembling those seen with urofollitropin or highly purified urofollitropin. " 01/01/1998 - "Recombinant follicle-stimulating hormone (FSH; Puregon) is more efficient than urinary FSH (Metrodin) in women with clomiphene citrate-resistant, normogonadotropic, chronic anovulation: a prospective, multicenter, assessor-blind, randomized, clinical trial. "

Related Drugs and Biologics

1.	Estradiol (Estrace)
2.	Menotropins (Humegon)
3.	Human Follicle Stimulating Hormone (Gonal F)
4.	Follicle Stimulating Hormone (Follitropin)
5.	Urofollitropin (Bravelle)
6.	Steroids
7.	Chorionic Gonadotropin (Human Chorionic Gonadotropin)
8.	Estrogens (Estrogen)
9.	Clomiphene (Clomifene)
10.	Triptorelin (Trelstar)

Related Therapies and Procedures

1.	Intravenous Injections