Imino Sugars

Sugars in which the OXYGEN is replaced by a NITROGEN atom. This substitution prevents normal METABOLISM resulting in inhibition of GLYCOSIDASES and GLYCOSYLTRANSFERASES.

Also Known As:

Networked: 24 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Butters, Terry D: 8 articles (06/2013 - 01/2002)
2.	Platt, Frances M: 6 articles (12/2007 - 01/2002)
3.	Dwek, Raymond A: 5 articles (11/2007 - 01/2002)
4.	Ohno, Kazuki: 4 articles (06/2011 - 05/2008)
5.	Sakuraba, Hitoshi: 4 articles (06/2011 - 05/2008)
6.	Tajima, Youichi: 4 articles (06/2011 - 05/2008)
7.	van der Spoel, Aarnoud C: 4 articles (12/2007 - 12/2002)
8.	Saito, Seiji: 3 articles (06/2011 - 04/2009)
9.	Tsukimura, Takahiro: 3 articles (06/2011 - 04/2009)
10.	Butters, T D: 2 articles (08/2013 - 08/2000)

Related Diseases

1.	Gaucher Disease (Gaucher's Disease) 03/01/2009 - "Promising results of the chaperone effect caused by imino sugars and aminocyclitol derivatives on mutant glucocerebrosidases causing Gaucher disease." 01/01/2002 - "Two such approaches that use imino sugars to affect glycosylation enzymes now show considerable promise in the treatment of viral infections, such as hepatitis B, and glucosphingolipid storage disorders, such as Gaucher disease."
2.	Virus Diseases (Viral Diseases) 01/01/2002 - "Two such approaches that use imino sugars to affect glycosylation enzymes now show considerable promise in the treatment of viral infections, such as hepatitis B, and glucosphingolipid storage disorders, such as Gaucher disease."
3.	Hepatitis B 01/01/2002 - "Two such approaches that use imino sugars to affect glycosylation enzymes now show considerable promise in the treatment of viral infections, such as hepatitis B, and glucosphingolipid storage disorders, such as Gaucher disease."
4.	Viral Hemorrhagic Fevers (Viral Hemorrhagic Fever) 06/01/2013 - "Our study thus proves the concept that imino sugars are promising drug candidates for the management of viral hemorrhagic fever caused by variety of viruses."
5.	Infertility (Sterility) 12/15/2007 - "Reversible infertility in male mice after oral administration of alkylated imino sugars: a nonhormonal approach to male contraception. " 11/09/2007 - "This process can be pharmacologically disturbed in C57BL/6 mice, and thus infertility can be induced, by small molecular sugar-like compounds (alkylated imino sugars). " 12/24/2002 - "Reversible infertility in male mice after oral administration of alkylated imino sugars: a nonhormonal approach to male contraception." 04/01/2005 - "Reversible infertility can be induced in male mice by oral administration of the alkylated imino sugars N-butyldeoxynojirimycin (NB-DNJ) and N-butyldeoxygalactonojirimycin (NB-DGJ). "

Related Drugs and Biologics

1.	Enzymes
2.	miglustat (Zavesca)
3.	Glucosidases
4.	Antiviral Agents (Antivirals)
5.	alpha-Glucosidases (Acid Maltase)
6.	Sugars
7.	Glycosphingolipids
8.	Glycoside Hydrolases (Endoglycosidases)
9.	Glycoproteins (Glycoprotein)
10.	Glycolipids

Related Therapies and Procedures

1.	Therapeutics
2.	Oral Administration
3.	Contraception (Birth Control)