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Prenatal Injuries

Subscribe to New Research on Prenatal Injuries

Damages to the EMBRYO, MAMMALIAN or the FETUS before BIRTH. Damages can be caused by any factors including biological, chemical, or physical.

Also Known As:

Injuries, Prenatal; Injury, Prenatal; Prenatal Injury

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Female Urogenital Diseases and Pregnancy Complications
- Pregnancy Complications: 986
  - Prenatal Injuries: 8
    - Prenatal Exposure Delayed Effects

Related Diseases

1.	Wounds and Injuries (Trauma)
2.	Premature Birth (Birth, Premature)
3.	Turner Syndrome (Turner's Syndrome)
4.	Paranoid Schizophrenia (Delusional Disorder)
5.	Schizophrenia (Dementia Praecox)

Experts

1.	Firl, D J: 1 article (07/2014)
2.	Robinson, S: 1 article (07/2014)
3.	Jantzie, L L: 1 article (07/2014)
4.	Wilson, C G: 1 article (07/2014)
5.	Getsy, P M: 1 article (07/2014)
6.	Miller, R H: 1 article (07/2014)
7.	Tonyushkina, Ksenia N: 1 article (01/2012)
8.	Dunbar, Nancy S: 1 article (01/2012)
9.	O'Connor, Stephen: 1 article (01/2012)
10.	Paul, Lynn K: 1 article (03/2011)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Prenatal Injuries:

1.	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/01/2008 - "Analysis of the specific features of an inflammatory reaction, wound contraction, the synthesis of cell mediators, cytokines, growth factors, and extracellular matrix modulators in response to a prenatal injury has allowed the discussion of the factors contributing to scar-free healing and the possible ways of minimizing fibrosis."
2.	Butyric Acid (Butanoic Acid)IBA 06/01/2010 - "To test the hypothesis that prenatal injury impairs the developmental switch of gamma-amino butyric acid (GABA)ergic synapses from excitatory to inhibitory, thereby disrupting cortical circuit formation and predisposing to epilepsy, we used immunohistochemistry to compare the expression of cation-chloride transporters that developmentally regulate postsynaptic GABAergic discharges in postmortem cerebral samples from infants born preterm with known white matter injury (n = 11) with that of controls with minimal white matter gliosis (n = 7). "
3.	Lactic Acid FDA LinkGeneric 09/01/1999 - "A false-negative MRS finding (normal lactate/choline but abnormal outcome) was seen in a patient who had an apparent prenatal injury. "
4.	CytokinesIBA 11/01/2008 - "Analysis of the specific features of an inflammatory reaction, wound contraction, the synthesis of cell mediators, cytokines, growth factors, and extracellular matrix modulators in response to a prenatal injury has allowed the discussion of the factors contributing to scar-free healing and the possible ways of minimizing fibrosis."
5.	Glycine (Aminoacetic Acid)FDA LinkGeneric 02/01/2006 - "Prospective treatment with this regimen can favorably modify the early neonatal course of severe NKH but does not prevent the poor long-term outcome, suggesting glycine-induced prenatal injury and/or ongoing postnatal damage."
6.	gamma-Aminobutyric Acid (GABA)IBA 06/01/2010 - "To test the hypothesis that prenatal injury impairs the developmental switch of gamma-amino butyric acid (GABA)ergic synapses from excitatory to inhibitory, thereby disrupting cortical circuit formation and predisposing to epilepsy, we used immunohistochemistry to compare the expression of cation-chloride transporters that developmentally regulate postsynaptic GABAergic discharges in postmortem cerebral samples from infants born preterm with known white matter injury (n = 11) with that of controls with minimal white matter gliosis (n = 7). "
7.	Erythropoietin FDA Link 07/01/2014 - "Further, administration of erythropoietin (EPO) in a clinically relevant postnatal dosing regimen following the prenatal injury protects the developing brain by reducing calpain activity, restoring oligomeric KCC2 expression and attenuating KCC2 fragmentation, thus providing the first report of a safe therapy to address deficits in KCC2 expression. "
8.	Choline (Choline Chloride)IBA 09/01/1999 - "A false-negative MRS finding (normal lactate/choline but abnormal outcome) was seen in a patient who had an apparent prenatal injury. "
9.	Carbon MonoxideIBA 10/01/1991 - "In twins, prenatal insults (e.g., ischemia) frequently do not affect both co-twins to the same extent, so we examined seven putative markers of prenatal injury to the hand in 24 MZ twin pairs discordant for schizophrenia or delusional disorder. "
10.	CalpainIBA 07/01/2014 - "Further, administration of erythropoietin (EPO) in a clinically relevant postnatal dosing regimen following the prenatal injury protects the developing brain by reducing calpain activity, restoring oligomeric KCC2 expression and attenuating KCC2 fragmentation, thus providing the first report of a safe therapy to address deficits in KCC2 expression. "