Laser-Assisted Subepithelial Keratectomy (LASEK)

A surgical technique to correct REFRACTIVE ERRORS of the EYE, such as MYOPIA and ASTIGMATISM. In this method, a flap of CORNEAL EPITHELIUM is created by exposure of the area to dilute alcohol. The flap is lifted and then replaced after laser ablation of the subepithelial CORNEA.

Also Known As:

LASEK; Keratectomy, Subepithelial, Laser-Assisted; Laser Subepithelial Keratomileusis; Laser-Assisted Sub-Epithelial Keratomileusis; Subepithelial Keratectomy, Laser-Assisted; Subepithelial Keratomileusis, Laser-Assisted; Subepithelial Photorefractive Keratectomy; Keratectomies, Subepithelial Photorefractive; Keratectomy, Subepithelial Photorefractive; Laser Assisted Subepithelial Keratectomy; Laser-Assisted Subepithelial Keratectomies; Laser-Assisted Subepithelial Keratomileusis; Photorefractive Keratectomies, Subepithelial; Photorefractive Keratectomy, Subepithelial; Sub-Epithelial Keratomileusis, Laser-Assisted; Subepithelial Keratectomies, Laser-Assisted; Subepithelial Keratectomy, Laser Assisted; Subepithelial Keratomileusis, Laser; Subepithelial Keratomileusis, Laser Assisted; Subepithelial Photorefractive Keratectomies; Keratomileusis, Subepithelial, Laser-Assisted

Networked: 271 relevant articles (42 outcomes, 41 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Teus, Miguel A: 19 articles (01/2021 - 02/2007)
2.	de Benito-Llopis, Laura: 10 articles (12/2009 - 02/2007)
3.	Kim, Eung Kweon: 9 articles (04/2020 - 05/2002)
4.	Marshall, John: 8 articles (11/2018 - 05/2002)
5.	Gabler, Bernhard: 8 articles (09/2005 - 01/2002)
6.	Zhou, Xingtao: 7 articles (09/2021 - 02/2002)
7.	O'Keefe, Michael: 7 articles (06/2012 - 01/2008)
8.	McAlinden, Colm: 6 articles (11/2018 - 01/2010)
9.	Kirwan, Caitriona: 6 articles (02/2012 - 02/2007)
10.	Astle, William F: 6 articles (02/2011 - 12/2004)

Related Diseases

1.	Myopia 01/01/2017 - "Both LASEK and SMILE are safe and effective surgical options for the correction of high myopia. " 01/01/2015 - "Both standard PRK and no-alcohol LASEK offer safe and effective correction of low-moderate myopia in the long term without any statistically significant difference between the two groups." 12/01/2008 - "LASEK is a safe and effective procedure for correction of super high myopia, though there is still some regression happened after operation and the intraocular pressure should be observed during the follow-up periods." 12/01/2006 - "LASIK and LASEK are all safe and effective refractive surgery for high myopia." 03/01/2006 - "To investigate the efficacy of laser subepithelial keratomileusis (LASEK) for the correction of high myopia with the Schwind ESIRIS scanning spot laser (Schwind eye-tech-solutions Gmbh & Co, Kleinostheim, Germany). "
2.	Astigmatism 01/01/2018 - "Both FSBK and LASEK are safe and effective procedures to correct moderate to high myopic astigmatism. " 04/01/2014 - "The efficacy of LASEK was compared between those with and those without a significant amount of intraocular astigmatism. " 04/01/2014 - "Laser-assisted subepithelial keratectomy was less effective in correcting myopic astigmatism when astigmatism was mainly located at the internal optics. " 06/01/2006 - "Topography-assisted customized LASEK was effective in the correction of postkeratoplasty astigmatism. " 11/01/2015 - "To compare the efficacy of correcting myopic astigmatism with femtosecond laser small-incision lenticule extraction (SMILE, Carl Zeiss Meditec AG) versus laser-assisted subepithelial keratectomy (LASEK). "
3.	Amblyopia (Lazy Eye) 04/01/2009 - "The current literature shows that LASIK, PRK, and LASEK show promising results in children with refractive amblyopia over the intermediate follow-up period. " 12/01/2007 - "To assess the refractive, visual acuity, and binocular results of laser-assisted subepithelial keratectomy (LASEK) for anisomyopia, anisohyperopia, and anisoastigmatia in children with various levels of amblyopia secondary to the anisometropic causes. " 12/01/2007 - "Laser-assisted subepithelial keratectomy for anisometropic amblyopia in children: outcomes at 1 year." 01/01/2004 - "Laser-assisted subepithelial keratectomy and photorefractive keratectomy versus conventional treatment of myopic anisometropic amblyopia in children." 01/01/2016 - " surgery in children, multizonal LASEK and pIOL Verisyse implantation, are effective and safe methods for correction of high myopic anisometropia, and has an important role in the treatment of amblyopia in children when contact lens intolerance. "
4.	Pain (Aches) 02/11/2019 - "Conclusion: TPRK has the advantages of faster early vision recovery and significantly less pain over LASEK. " 02/11/2019 - "Results: At 3 days, the pain score was 1 (0,3) in the LASEK group versus 0 (0,1) in the TPRK group (Z=5.643, P=0.001). " 11/01/2018 - "The surface under the cumulative ranking curve ranking results (best to worst) showed laser epithelial keratomileusis (LASEK) ranked highest for efficacy, predictability, safety, and day 1 pain scores. " 01/01/2017 - "LASEK was developed as an alternative to PRK to address the issue of pain associated with epithelial debridement used for PRK. " 09/01/2014 - "At postoperative 1 day, the mean subjective pain score in the LASEK group was 3.2 ± 1.88 and 4.43 ± 1.61 in T-PRK group (P = 0.008). "
5.	Hyperopia (Hypermetropia) 04/01/2007 - "To investigate the efficacy of laser epithelial keratomileusis (LASEK) for the correction of hyperopia using a 7.0-mm optical zone and a 9.0-mm total ablation zone diameter with the Schwind ESIRIS flying-spot laser. " 11/01/2003 - "This prospective comparative single-surgeon study included 216 eyes of 108 patients with hyperopia who received PRK in 1 eye and LASEK in the contralateral eye. " 11/01/2003 - "Laser-assisted subepithelial keratectomy for hyperopia up to +5.00 D provided good visual and refractive results. " 11/01/2003 - "To evaluate and compare the efficacy, safety, predictability, and stability of laser-assisted subepithelial keratectomy (LASEK) and photorefractive keratectomy (PRK) for low to moderate hyperopia with a 2-year follow-up. " 11/01/2003 - "Laser-assisted subepithelial keratectomy and photorefractive keratectomy for the correction of hyperopia. "

Related Drugs and Biologics

1.	Mitomycin (Mitomycin-C)
2.	4-hexyloxyaniline (HOA)
3.	Solutions
4.	Indomethacin (Indometacin)
5.	visthesia
6.	Collagen
7.	Ethanol (Ethyl Alcohol)
8.	Ketorolac
9.	Vasoactive Intestinal Peptide (VIP (Vasoactive Intestinal Peptide))
10.	Tramadol (K315)

Related Therapies and Procedures

1.	Laser In Situ Keratomileusis (LASIK)
2.	Laser-Assisted Subepithelial Keratectomy (LASEK)
3.	Lasers (Laser)
4.	Photorefractive Keratectomy
5.	Refractive Surgical Procedures