beta-N-Acetyl-Galactosaminidase

A hexosiminidase that specifically hydrolyzes terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides.

Also Known As:

N-Acetyl-beta-Galactosaminidase; beta-N-Acetylgalactosaminidase; N Acetyl beta Galactosaminidase; beta N Acetyl Galactosaminidase; beta N Acetylgalactosaminidase

Networked: 8 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Glycoside Hydrolases: 871
      - Hexosaminidases: 1037
        beta-N-Acetyl-Galactosaminidase: 8

Experts

1.	Aruldhas, M M: 1 article (08/2001)
2.	Arunakaran, J: 1 article (08/2001)
3.	Maran, R R: 1 article (08/2001)
4.	Priyadarsini, D: 1 article (08/2001)
5.	Udhayakumar, R C: 1 article (08/2001)

Related Diseases

1.	Uterine Cervical Neoplasms (Cancer of the Cervix) 10/01/1969 - "Histochemical studies on N-acetyl-beta-galactosaminidase and N-acetyl-beta-glucosaminidase in the cancer of the uterine cervix."
2.	Hyperthyroidism 08/01/2001 - "Cauda epididymal beta-N-acetylgalactosaminidase activity was decreased in 30 day and increased in 60 day hyperthyroid rats. " 08/01/2001 - "Hyperthyroidism consistently increased caput and corpus beta-N-acetylgalactosaminidase activity irrespective of the duration. " 08/01/2001 - "Hyperthyroidism induced changes in caput beta-galactosidase, beta-N-acetylgalactosaminidases, corpus beta-N-acetylglucosaminidase and cauda beta-N-acetylgalactosaminidase which were irreversible while the remaining actvities were brought back to normal when T4 treatment was withdrawn. " 06/01/1998 - "Prostatic [anterior (coagulating glands), dorsolateral and ventral prostates] beta-glucosidase, beta-galactosidase, beta-N-acetylglucosaminidase and beta-N-acetylgalactosaminidase activities increased uniformly in hyperthyroid, and decreased in thyroidectomized, rats. "
3.	Tay-Sachs Disease 10/01/1982 - "Using this substrate, we found a striking deficiency of beta-N-acetylgalactosaminidase activity in the cultured skin fibroblasts of patients with Sandhoff disease and Tay-Sachs disease. "
4.	Sandhoff Disease (Sandhoff's Disease) 10/01/1982 - "Using this substrate, we found a striking deficiency of beta-N-acetylgalactosaminidase activity in the cultured skin fibroblasts of patients with Sandhoff disease and Tay-Sachs disease. "
5.	Osteoarthritis 10/01/1993 - "beta-Glycosidases (N-acetyl-beta-glucosaminidase, N-acetyl-beta-galactosaminidase, beta-glucuronidase) were assayed in temporomandibular joint (TMJ) synovial fluid obtained from 23 patients with closed lock TMJ internal derangement (ID), four with closed-lock TMJ osteoarthritis (OA), and 13 with normal controls (N). "

Related Drugs and Biologics

1.	Hexosaminidases (Hexosaminidase)
2.	Acetylglucosaminidase (NAGase)
3.	beta-Galactosidase (Lactaid)
4.	beta-Glucosidase
5.	beta-Mannosidase
6.	alpha-Mannosidase (LAMAN)
7.	Zymosan
8.	Hydrolases
9.	Glycoside Hydrolases (Endoglycosidases)
10.	Glucuronidase