Guided Tissue Regeneration

Procedures for enhancing and directing tissue repair and renewal processes, such as BONE REGENERATION; NERVE REGENERATION; etc. They involve surgically implanting growth conducive tracks or conduits (TISSUE SCAFFOLDING) at the damaged site to stimulate and control the location of cell repopulation. The tracks or conduits are made from synthetic and/or natural materials and may include support cells and induction factors for CELL GROWTH PROCESSES; or CELL MIGRATION.

Also Known As:

Networked: 344 relevant articles (24 outcomes, 78 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Wang, Hom-Lay: 6 articles (01/2020 - 04/2002)
2.	Górska, Renata: 4 articles (03/2020 - 07/2018)
3.	Górski, Bartłomiej: 4 articles (03/2020 - 07/2018)
4.	Chambrone, Leandro: 4 articles (10/2018 - 09/2008)
5.	Sallum, Enilson A: 4 articles (06/2006 - 09/2003)
6.	Jalowski, Stanisław: 3 articles (03/2020 - 11/2018)
7.	Zaremba, Maciej: 3 articles (03/2020 - 11/2018)
8.	Sukekava, Flávia: 3 articles (10/2018 - 04/2009)
9.	Lima, Luiz A: 3 articles (04/2010 - 09/2008)
10.	Pustiglioni, Francisco E: 3 articles (04/2010 - 09/2008)

Related Diseases

1.	Furcation Defects 01/01/1999 - "The conclusion was that within the limits of this study, resorbable test barrier can be used for guided tissue regeneration (GTR) in class II furcation defects with at least as good results as those achieved with non-resorbable control barrier but with the additional benefit of only one operation." 02/01/2016 - "Guided tissue regeneration (GTR) therapy has shown good results in the management of mandibular molar class II furcation defects. " 04/01/1995 - "The present experiment on guided tissue regeneration had 2 objectives namely: (i) to study if an improved anchorage of the soft tissue flaps during the initial healing period after membrane placement would reduce the tendency for soft tissue recession and allow for healing of also large furcation defects; (ii) to determine if the use of biodegradable membranes in GTR procedures may promote new attachment formation in degree III furcation defects. " 11/01/2015 - "The present study was undertaken to evaluate the efficacy of freeze-dried bone allograft (FDBA) with and without bioabsorbable guided tissue regeneration (GTR) membrane Healiguide(®) in the treatment of Grade II furcation defects. " 11/01/2014 - "The purpose of the study was to evaluate the efficacy of combination therapy using anorganic bovine bone graft and resorbable guided tissue regeneration (GTR) membrane versus open flap debridement alone in the management of Grade II furcation defects in mandibular molars. "
2.	Gingival Recession 01/01/2015 - "Connective tissue grafts were statistically significantly superior to guided tissue regeneration for improvement in gingival recession reduction." 04/01/2010 - "The results indicated a significantly greater reduction in gingival recession and gain in keratinized tissue for subepithelial connective tissue grafts (SCTGs) compared to guided tissue regeneration (GTR) with bioabsorbable membranes (GTR bms). " 10/01/2008 - "[Therapeutic efficacy of guided tissue regeneration and connective tissue autotransplants with periosteum in the management of gingival recession]." 11/01/2018 - "Guided tissue regeneration-based root coverage has emerged as a promising treatment modality in the treatment of gingival recession. " 09/01/2015 - "Guided tissue regeneration (GTR) based root coverage using different allograft membranes has been utilized to correct gingival recession defects with promising results. "
3.	Aggressive Periodontitis (Periodontosis) 07/01/2016 - "This study reports the radiographic analysis of a split-mouth, single-blinded, randomised controlled clinical trial which was designed to compare the efficacy of simplified papilla preservation flap (SPPF) with or without guided tissue regeneration (GTR) in patients with aggressive periodontitis (AgP). " 07/01/2019 - "The main objectives of this study were (1) to evaluate bone/graft density alterations by digital subtraction radiography; (2) to determine factors associated with favorable clinical and radiographic outcomes, and (3) to report on patient morbidity after guided tissue regeneration (GTR) in aggressive periodontitis (AgP) patients. " 07/01/2016 - "The aim of this study was to compare clinical outcomes between guided tissue regeneration (GTR) and access flap (AF) surgery in patients with aggressive periodontitis (AgP). " 01/01/2007 - "Electron microprobe analysis was used to study the nature of the newly-formed hard tissue 3 years after treatment with guided tissue regeneration in a patient with localized aggressive periodontitis. " 06/01/1996 - "The objective of this study was to compare guided tissue regeneration (GTR) and osseous surgery (OS) in treatment of early-onset periodontitis. "
4.	Periodontal Diseases (Periodontal Disease) 01/01/2006 - "In dentistry, guided tissue regeneration is effective in the treatment of periodontal diseases. " 01/01/2023 - "This study evaluated the clinical success rate of guided tissue regeneration (GTR) for treating advanced periodontal disease in a large canine cohort. " 11/01/2006 - "The purpose of this study was to compare the clinical and radiological effectiveness of platelet pellet/guided tissue regeneration (PP/GTR) and bioactive glass/GTR (BG/GTR) treatments in patients with periodontal disease. " 02/01/1994 - "The aim of this study was to evaluate the predictability of guided tissue regeneration (GTR), using ePTFE-membranes (Gore-Tex) in the treatment of advanced periodontal disease. " 12/31/2023 - "Guided tissue regeneration (GTR) and guided bone regeneration (GBR) have made great progress in periodontal disease treatment, but some deficiencies existed in commercial materials of GTR and GBR. "
5.	Peri-Implantitis 04/01/1995 - "This paper presents a novel treatment approach aimed at the successful regeneration of bone lost to peri-implantitis using guided tissue regeneration (GTR). " 06/01/1994 - "Implant-tissue interfaces following treatment of peri-implantitis using guided tissue regeneration: a light and electron microscopic study." 01/01/1993 - "This study evaluated the treatment of ligature-induced peri-implantitis using guided tissue regeneration (GTR) around submerged and nonsubmerged implants in beagle dogs. " 01/01/1993 - "Treatment of ligature-induced peri-implantitis using guided tissue regeneration: a clinical and histologic study in the beagle dog."

Related Drugs and Biologics

1.	Collagen
2.	Collagen Type I (Type I Collagen)
3.	Bio-Oss
4.	Polytetrafluoroethylene (Teflon)
5.	poly(lactide) (polylactic acid)
6.	Durapatite (Hydroxylapatite)
7.	Intercellular Signaling Peptides and Proteins (Growth Factors)
8.	Tetracycline (Achromycin)
9.	tricalcium phosphate
10.	Metronidazole (Metric)

Related Therapies and Procedures

1.	Therapeutics
2.	Debridement
3.	Operative Surgical Procedures
4.	Oral Surgery (Maxillofacial Surgery)
5.	Ligation