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Flavones

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A group of 4-keto-FLAVONOIDS.

Also Known As:

2-Phenyl-2-Ene-Benzopyran-4-One Compounds

Networked: 231 relevant articles (11 outcomes, 44 trials/studies)

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Bio-Agent Context: Research Results

Heterocyclic Compounds: 60
- Pyrans: 5
  - Benzopyrans: 11
    - Chromones: 27
      - Flavonoids: 2256
        Flavones: 231
        Apigenin: 440
        Luteolin: 426
        flavone: 310
        Diosmin: 146
        nobiletin: 121
        tangeretin: 52
        Flavoxate: 43
        acacetin: 33
        hispidulin: 22
        6,7-dihydroxyflavone: 21
        protoapigenone: 20
        P276-00: 11
        5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone: 9
        eupafolin: 9
        genkwanin: 7
        LYG 202: 6
        cirsimaritin: 5
        luteolin-7-O-glucoside: 5
        xanthomicrol: 5
        3',4'-dimethoxyflavone: 4
        2'-nitroflavone: 3
        cirsiliol: 3
        cirsimarin: 3
        nevadensin: 3
        3,4,11-trihydroxy-2-(hydroxymethyl)-8-(4-hydroxyphenyl)-3,4,4a,11b-tetrahydro-2H,10H-pyrano(2',3'-4,5)furo(3,2-g)chromen-10-one: 2
        4'-demethylnobiletin: 2
        4-hydroxylonchocarpin: 2
        5,7,3'-trihydroxy-3,4'-dimethoxyflavone: 2
        artocarpesin: 2
        bavachalcone: 2
        calycopterin: 2
        cirsilineol: 2
        isocryptomerin: 2
        licoflavone C: 2
        norwogonin: 2
        salvigenin: 2
        zapotin: 2
        3',4'-dihydroxy-5,6,7,8-tetramethoxyflavone: 1
        5,7-dihydroxy-6,4'-dimethoxyflavone: 1
        8-prenylapigenin: 1
        artocarpanone: 1
        cochliophilin A: 1
        corylifol A: 1
        icariside I: 1
        isocannflavin B: 1
        jezonocinol B: 1
        karanjabiflavone: 1
        ladanein: 1
        pedalitin: 1
        persicarin: 1
        (1''R)-5,4',1''-trihydroxy-6,7-(3'',3''-dimethylchroman)flavone
        2''-O-beta-D-galactosylisoswertisin
        2''-O-veratroylisoswertisin
        2',4',7-trimethoxyflavone
        2-(4-(((3-ethylheptanoyl)oxy)methyl)phenyl)-5,8-dimethoxy-4-oxo-4H-chromen-7-yl 4-methylbenzoate
        2-(4-(((3-ethylheptanoyl)oxy)methyl)phenyl)-5-methoxy-4-oxo-4H-chromen-7-yl 3-(4-methoxyphenyl)-2-propenoate
        3''-O-2-methylbutyrylisoswertiajaponin
        3''-O-2-methylbutyrylvitexin
        3',4',7-trimethoxyflavone
        3',4'-didemethylnobiletin
        3',5'-dimethoxyflavone
        3',5,6-trihydroxy-3,4',7-trimethoxyflavone
        3'-(2'',4''-dihydroxybenzyloxy)acanthophorin B
        3'-demethylnobiletin
        3'-dimethylaminoflavone
        3,5,6,7-tetrahydroxy-3',4'-dimethoxyflavone-5-beta-D-xylopyranoside
        3,6-dimethoxy-6'',6''-dimethylchromeno(2'',3''-7,8)flavone
        3-hydroxy-4'-(N,N-dimethylamino)flavone
        3-methoxy-6-(3-methylbut-2-enyloxy)-6'',6''-dimethylchromeno(2'',3''-7,8)flavone
        3-O-((rhamnopyranosyl)oxy)-7-O-((acetyl)glucopyranosyl-1-4)-(6-O-(4-hydroxycinnamoyl)glucopyranosyl-1-2-rhamnopyranosyloxy)kaempferol
        4',5,6,7,8-pentahydroxy-3-methoxyflavone
        4'-(9'-ethylene-16'-methylnon-9',15'-dien-7',11'-oate)-5,7,3'-trimethoxyflavone
        4'-(9'-ethylene-16'-methylnon-9',15'-dien-7',11'-oate)-5,7-dimethoxyflavone
        4'-methoxy-vitexin 7-O-beta-D-xylopyranoside
        5,2',4'-trihydroxy-6,7,5'-trimethoxyflavone
        5,3'-dihydroxy-3,6,7,4',5'-pentamethoxyflavone
        5,4'-dihydroxy-3',5'-dimethoxy-7-O-beta-glucopyranosylflavone
        5,4'-dihydroxy-6,7-methylenedioxy-3'-methoxyflavone
        5,6,2',3',5',6'-hexamethoxyflavone
        5,6,2',3',6'-pentamethoxyflavone
        5,6,7,8,3',4',5'-heptamethoxyflavone
        5,6,7,8,3'-pentamethoxy-4',5'-methylenedioxyflavone
        5,6,7,8-tetrahydroxy-3-methoxyflavone
        5,6-dihydroxy-7,8,3',4'-tetramethoxyflavone
        5,7,4',5'',7'',3''',4'''-heptahydroxyflavanone(3-8'')flavone
        5,7,4'-trihydroxy-3,8-dimethoxylflavone 5-O-beta-D-gluco-pyranoside
        5,7,4'-trihydroxy-6,3'-dimethoxyflavone-7-O-alpha-L-arabinopyranosyl(1-6)-O-beta-D-galactopyranoside
        5,7-dihydroxy-3,6,8,2',4',5'-hexamethoxyflavone
        5,7-dihydroxy-6,3',4'-trimethoxyflavone
        5,8-dihydroxy-flavone-7-O-beta-D-glucuronide
        5-carboxybutylester-4',7-dihydroxyflavone
        5-carboxyethylester-4',7-dihydroxyflavone
        5-carboxymethyl-4',7-dihydroxyflavone
        5-hydroxy-2-(1-hydroxy-4-oxocyclohexa-2,5-dienyl)-7-methoxy-4H-chromen-4-one
        5-hydroxy-3,7,8,3,4-pentamethoxyflavone
        5-hydroxy-8-methoxyl-flavone-7-O-beta-D-glucuronide
        5-O-demethylnobiletin
        6''-O-(2'''-methylbutyryl)isoswertiajaponin
        6''-O-(2'''-methylbutyryl)isoswertisin
        6,2',4'-trimethoxyflavone
- 2-Ring Heterocyclic Compounds
  - Benzopyrans: 11
    - Chromones: 27
      - Flavonoids: 2256
        Flavones: 231
        Apigenin: 440
        Luteolin: 426
        flavone: 310
        Diosmin: 146
        nobiletin: 121
        tangeretin: 52
        Flavoxate: 43
        acacetin: 33
        hispidulin: 22
        6,7-dihydroxyflavone: 21
        protoapigenone: 20
        P276-00: 11
        5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone: 9
        eupafolin: 9
        genkwanin: 7
        LYG 202: 6
        cirsimaritin: 5
        luteolin-7-O-glucoside: 5
        xanthomicrol: 5
        3',4'-dimethoxyflavone: 4
        2'-nitroflavone: 3
        cirsiliol: 3
        cirsimarin: 3
        nevadensin: 3
        3,4,11-trihydroxy-2-(hydroxymethyl)-8-(4-hydroxyphenyl)-3,4,4a,11b-tetrahydro-2H,10H-pyrano(2',3'-4,5)furo(3,2-g)chromen-10-one: 2
        4'-demethylnobiletin: 2
        4-hydroxylonchocarpin: 2
        5,7,3'-trihydroxy-3,4'-dimethoxyflavone: 2
        artocarpesin: 2
        bavachalcone: 2
        calycopterin: 2
        cirsilineol: 2
        isocryptomerin: 2
        licoflavone C: 2
        norwogonin: 2
        salvigenin: 2
        zapotin: 2
        3',4'-dihydroxy-5,6,7,8-tetramethoxyflavone: 1
        5,7-dihydroxy-6,4'-dimethoxyflavone: 1
        8-prenylapigenin: 1
        artocarpanone: 1
        cochliophilin A: 1
        corylifol A: 1
        icariside I: 1
        isocannflavin B: 1
        jezonocinol B: 1
        karanjabiflavone: 1
        ladanein: 1
        pedalitin: 1
        persicarin: 1
        (1''R)-5,4',1''-trihydroxy-6,7-(3'',3''-dimethylchroman)flavone
        2''-O-beta-D-galactosylisoswertisin
        2''-O-veratroylisoswertisin
        2',4',7-trimethoxyflavone
        2-(4-(((3-ethylheptanoyl)oxy)methyl)phenyl)-5,8-dimethoxy-4-oxo-4H-chromen-7-yl 4-methylbenzoate
        2-(4-(((3-ethylheptanoyl)oxy)methyl)phenyl)-5-methoxy-4-oxo-4H-chromen-7-yl 3-(4-methoxyphenyl)-2-propenoate
        3''-O-2-methylbutyrylisoswertiajaponin
        3''-O-2-methylbutyrylvitexin
        3',4',7-trimethoxyflavone
        3',4'-didemethylnobiletin
        3',5'-dimethoxyflavone
        3',5,6-trihydroxy-3,4',7-trimethoxyflavone
        3'-(2'',4''-dihydroxybenzyloxy)acanthophorin B
        3'-demethylnobiletin
        3'-dimethylaminoflavone
        3,5,6,7-tetrahydroxy-3',4'-dimethoxyflavone-5-beta-D-xylopyranoside
        3,6-dimethoxy-6'',6''-dimethylchromeno(2'',3''-7,8)flavone
        3-hydroxy-4'-(N,N-dimethylamino)flavone
        3-methoxy-6-(3-methylbut-2-enyloxy)-6'',6''-dimethylchromeno(2'',3''-7,8)flavone
        3-O-((rhamnopyranosyl)oxy)-7-O-((acetyl)glucopyranosyl-1-4)-(6-O-(4-hydroxycinnamoyl)glucopyranosyl-1-2-rhamnopyranosyloxy)kaempferol
        4',5,6,7,8-pentahydroxy-3-methoxyflavone
        4'-(9'-ethylene-16'-methylnon-9',15'-dien-7',11'-oate)-5,7,3'-trimethoxyflavone
        4'-(9'-ethylene-16'-methylnon-9',15'-dien-7',11'-oate)-5,7-dimethoxyflavone
        4'-methoxy-vitexin 7-O-beta-D-xylopyranoside
        5,2',4'-trihydroxy-6,7,5'-trimethoxyflavone
        5,3'-dihydroxy-3,6,7,4',5'-pentamethoxyflavone
        5,4'-dihydroxy-3',5'-dimethoxy-7-O-beta-glucopyranosylflavone
        5,4'-dihydroxy-6,7-methylenedioxy-3'-methoxyflavone
        5,6,2',3',5',6'-hexamethoxyflavone
        5,6,2',3',6'-pentamethoxyflavone
        5,6,7,8,3',4',5'-heptamethoxyflavone
        5,6,7,8,3'-pentamethoxy-4',5'-methylenedioxyflavone
        5,6,7,8-tetrahydroxy-3-methoxyflavone
        5,6-dihydroxy-7,8,3',4'-tetramethoxyflavone
        5,7,4',5'',7'',3''',4'''-heptahydroxyflavanone(3-8'')flavone
        5,7,4'-trihydroxy-3,8-dimethoxylflavone 5-O-beta-D-gluco-pyranoside
        5,7,4'-trihydroxy-6,3'-dimethoxyflavone-7-O-alpha-L-arabinopyranosyl(1-6)-O-beta-D-galactopyranoside
        5,7-dihydroxy-3,6,8,2',4',5'-hexamethoxyflavone
        5,7-dihydroxy-6,3',4'-trimethoxyflavone
        5,8-dihydroxy-flavone-7-O-beta-D-glucuronide
        5-carboxybutylester-4',7-dihydroxyflavone
        5-carboxyethylester-4',7-dihydroxyflavone
        5-carboxymethyl-4',7-dihydroxyflavone
        5-hydroxy-2-(1-hydroxy-4-oxocyclohexa-2,5-dienyl)-7-methoxy-4H-chromen-4-one
        5-hydroxy-3,7,8,3,4-pentamethoxyflavone
        5-hydroxy-8-methoxyl-flavone-7-O-beta-D-glucuronide
        5-O-demethylnobiletin
        6''-O-(2'''-methylbutyryl)isoswertiajaponin
        6''-O-(2'''-methylbutyryl)isoswertisin
        6,2',4'-trimethoxyflavone

Experts

1.	Chen, Zhi-Wu: 7 articles (01/2015 - 01/2007)
2.	La Vecchia, Carlo: 7 articles (01/2010 - 04/2005)
3.	Walle, Thomas: 7 articles (11/2009 - 05/2007)
4.	Bosetti, Cristina: 6 articles (01/2010 - 04/2005)
5.	Negri, Eva: 6 articles (01/2010 - 04/2005)
6.	Lagiou, Pagona: 5 articles (01/2010 - 04/2005)
7.	Franceschi, Silvia: 5 articles (08/2008 - 04/2005)
8.	Rossi, Marta: 4 articles (01/2010 - 08/2006)
9.	Talamini, Renato: 4 articles (08/2008 - 01/2006)
10.	Montella, Maurizio: 4 articles (08/2008 - 04/2005)

Related Diseases

1.	Reperfusion Injury 01/01/2007 - "The present study was to investigate the effect of pharmacological preconditioning of total flavones of abelmoschl manihot (TFA) on cerebral ischemic reperfusion injury in rats. " 01/01/2007 - "Protective effect of pharmacological preconditioning of total flavones of abelmoschl manihot on cerebral ischemic reperfusion injury in rats." 01/01/2009 - "The purpose of this research was to demonstrate the protective effects and possible mechanisms of total flavones of rhododendra (TFR) against global cerebral ischemia reperfusion injury in rats. " 01/01/2009 - "Protective effects of total flavones of rhododendra against global cerebral ischemia reperfusion injury." 01/01/2008 - "This study was to investigate the protective effects and possible mechanisms of total flavones of rhododendra (TFR) against cerebral ischemia reperfusion injury in rats and mice. "
2.	Brain Ischemia (Cerebral Ischemia) 07/01/2012 - "To study the effect of total flavones of Rhododendron simsii (TFR) on the activation of ERK induced by cerebral ischemia-reperfusion in rats and its possible mechanism. " 01/01/2014 - "We for the first time investigated the effect and mechanism of the total flavones of Rhododendron simsii Planch (TFR), a widely-used Chinese herb for a thousand years, on vasodilatation and hyperpolarization in middle cerebral artery (MCA) of rats subject to global cerebral ischemia-reperfusion (CIR). " 07/01/2012 - "[Effect of total flavones of Rhododendra simsii on the activation of ERK induced by cerebral ischemia-reperfusion in rats]." 01/01/2009 - "The purpose of this research was to demonstrate the protective effects and possible mechanisms of total flavones of rhododendra (TFR) against global cerebral ischemia reperfusion injury in rats. " 01/01/2009 - "Protective effects of total flavones of rhododendra against global cerebral ischemia reperfusion injury."
3.	Neoplasms (Cancer) 01/01/2011 - "Thus, our study reveals a new mechanism of anti-cancer action of natural flavones and supports CDK9 as a therapeutic target in oncology." 06/27/2007 - "This study examined the growth inhibitory effects of structurally related polymethoxylated flavones in human cancer cells. " 11/25/2015 - "Flavones Inhibit the Activity of AKR1B10, a Promising Therapeutic Target for Cancer Treatment." 01/01/2015 - "Flavones found in plants display various biological activities, including anti-allergic, anti-viral, anti-inflammatory, anti-oxidation, and anti-tumor effects. " 10/01/2014 - "Flavones have received considerable attention because of their antiproliferative properties and selective effects on cancer cells, making them good candidates for use in cancer therapy. "
4.	Osteoporosis 05/01/2014 - "[Key words] total flavones of Epimedium leptorrhizum; ovariectomized rat; osteoporosis" 05/01/2014 - "To observe the effect of total flavones of Epimedium leptorrhizum (YYH-C) on osteoporosis in ovariectomized rats. " 05/01/2014 - "[Effect of total flavones of Epimedium leptorrhizum on osteoporosis in ovariectomized rats]." 01/01/2012 - "This study examined the efficacy of hydroalcoholic extract of dried clove buds, which is rich in phenolic compounds namely eugenol and eugenol derivatives (precursors of flavones, isoflavones and flavonoids), on different primary and secondary osteoporotic marker changes in an ovariectomised (OVX) rat model of osteoporosis. "
5.	Leishmaniasis 01/01/2015 - "The computer-aided drug design studies revealed good results against Leishmaniasis for flavones. "

Related Drugs and Biologics

1.	Flavonoids
2.	Isoflavones
3.	Flavonols
4.	Flavanones
5.	Luteolin
6.	Apigenin
7.	Quercetin
8.	wogonin
9.	Eugenol
10.	Alkaloids

Related Therapies and Procedures

1.	Chinese Traditional Medicine (Traditional Chinese Medicine)
2.	Lasers (Laser)