Eosinophil-Derived Neurotoxin

05/01/2000 - "Development of a novel enzyme-linked immunosorbent assay for blood and urinary eosinophil-derived neurotoxin: a preliminary study in patients with bronchial asthma."
11/01/2015 - "Serum eosinophil-derived neurotoxin: Correlation with persistent airflow limitation in adults with house-dust mite allergic asthma."
01/01/2013 - "Human eosinophil derived neurotoxin (EDN), a granule protein secreted by activated eosinophils, is a biomarker for asthma in children. "
01/01/2013 - "Eosinophil-derived neurotoxin: a novel biomarker for diagnosis and monitoring of asthma."
06/01/2010 - "Eosinophil-derived neurotoxin in childhood asthma: correlation with disease severity."

01/01/2004 - "Peak expiratory flow rate and urinary eosinophil protein X were used as measures of lung function and inflammation. "
11/01/1999 - "It is suggested that urinary eosinophil protein X (EPX) is a noninvasive tool to monitor bronchial inflammation in asthmatic children. "
03/01/2007 - "This study sought to evaluate the use of serum eosinophil-derived neurotoxin (EDN), which has been proposed as a marker of airway inflammation in asthma in the diagnosis and evaluation of the severity and bronchial hyperresponsiveness in childhood asthma. "
01/01/2007 - "The aim of this study was to investigate the relationship between urinary eosinophil protein X (uEPX) and asthma symptoms, lung function, and other markers of eosinophilic airway inflammation in asthmatic school children. "
01/01/2013 - "Urinary eosinophil protein X in childhood asthma: relation with changes in disease control and eosinophilic airway inflammation."

09/01/2004 - "To identify phenotypic differences in eosinophil-derived neurotoxin (EDN) content and release in eosinophils from healthy patients, those with allergy, and those with allergy and asthma. "
12/01/2000 - "Eosinophil cationic protein (ECP) and eosinophil-derived neurotoxin (EPX) are cytotoxic molecules involved in helminth infections and allergic reactions. "
01/01/1997 - "3. Circulating eosinophils of VKC patients show a typical activation phenotypic profile which is associated with increased serum level of eosinophil cationic protein and eosinophil-derived neurotoxin/protein X. A clinical study of the modulatory effect of cetirizine on the early and late phase of the allergic reaction as well as on the eosinophil activation and tissue recruitment following conjunctival allergen challenge is reported as an example of the need to evaluate eosinophil functions when investigating anti-allergic drugs. "
09/01/2001 - "We measured eosinophil protein X (EPX) and leukotriene E(4) (LTE(4)) in urine, as well as eosinophil cationic protein (ECP) in nasal lavages, in a random sample of 1-year-old children with a family history of atopy who participated in an international multicenter study on the prevention of allergy in Europe. "
04/01/2012 - "To assess, in a group of patients with IBD in remission or with a mild disease activity, whether serological markers of eosinophil activation, eosinophil cationic protein (ECP) and eosinophil protein X (EPX), are related to evidence of IgE hypersensitivity and to the eosinophilia in gut mucosa. "

01/01/2004 - "Concomitantly, the atopic eczema improved, and the concentration of urinary eosinophil protein X decreased significantly. "
06/01/2009 - "Serum eosinophil-derived neurotoxin in childhood atopic dermatitis: a useful marker of disease activity?"
12/01/2007 - "It has been reported that measurements of eosinophil-derived neurotoxin (EDN) may be useful for identifying eosinophil activities in allergic diseases including atopic dermatitis. "
10/01/2000 - "Urinary eosinophil protein X in children with atopic dermatitis: relation to atopy and disease activity."
08/01/2001 - "Urine eosinophil protein X (EPX) is an in vitro parameter of inflammation in atopic dermatitis of the adult age."

07/01/2012 - "We performed histologic analyses and immunohistochemical assays for eosinophil-derived neurotoxin (EDN), major basic protein (MBP), and tryptase, using biopsy samples from 10 patients with GERD (positive results from a pH study and response to proton pump inhibitors), Barrett's esophagus, or EoE (negative results from a pH study and positive response to budesonide). "