Eosinophil Granule Proteins

01/01/2011 - "We demonstrated that human atopic dermatitis skin has eosinophil granule proteins present in the same region as increased nerves. "
01/01/2008 - "Variation in genes encoding eosinophil granule proteins in atopic dermatitis patients from Germany."
11/01/2003 - "Micromolar concentrations of eosinophil granule proteins are often deposited in skin in eosinophil-associated cutaneous disorders such as atopic dermatitis. "
03/01/1998 - "Although the role of aqueous ECP and MBP was not elucidated, the results indicate that cytotoxic eosinophil granule proteins, especially MBP, are present in aqueous humor in certain cases of RD associated with atopic dermatitis."
05/01/1997 - "Immunofluorescent staining for eosinophil granule proteins in lesional skin of patients with atopic dermatitis shows extensive extracellular deposition throughout the upper dermis with relatively few intact eosinophils. "

12/01/2000 - "Eosinophil granule proteins in serum and urine of patients with helminth infections and atopic dermatitis."
05/01/1998 - "Eosinophil granule proteins may be important in both control of malaria infection and the pathogenesis of severe malaria."
09/01/2006 - "We investigated the in vivo roles of the eosinophil granule proteins eosinophil peroxidase (EPO) and major basic protein 1 (MBP) during infection with the rodent filaria Litomosoides sigmodontis. "
03/01/2014 - "To investigate whether eosinophils are involved in both protection and pathology during filarial nematode infection, we explored the role of eosinophils and their granule proteins, eosinophil peroxidase (EPO) and major basic protein-1 (MBP-1), during infection with Brugia malayi microfilariae. "
08/01/1995 - "The object of the present study was to study the question of selective release in vivo by means of serum measurements of the two eosinophil granule proteins eosinophil cationic protein (ECP) and eosinophil peroxidase (EPO) in acute infections. "

12/01/2002 - "This study was designed to demonstrate the presence of toxic eosinophil granule proteins in corneal tissue from a patient with corneal complications of atopic keratoconjunctivitis. "

06/01/1999 - "Assessment of eosinophil granule proteins in various body fluids: is there a relation to clinical variables in childhood asthma?"
05/01/1996 - "Eosinophils and eosinophil granule proteins may play an important role in the pathogenesis of asthma. "
11/01/1995 - "Eosinophil granule proteins may contribute to bronchial hyperresponsiveness in asthma. "
01/01/1994 - "Eosinophil-derived products, particularly eosinophil granule proteins, have been investigated as markers of eosinophil participation in the pathogenesis of asthma and, comparable to eosinophil numbers themselves, are possible predictors of impending exacerbations of allergic, as well as intrinsic bronchial asthma. "
09/01/1987 - "Evidence exists that eosinophil degranulation commonly occurs during bronchial asthma and eosinophil granule proteins are discharged onto damaged bronchial epithelium. "

07/01/2009 - "Prior electron microscopy (EM) of eosinophils in sites of inflammation noted losses of granule cores in the absence of granule exocytosis and suggested that eosinophil granule proteins might be released through piecemeal degranulation (PMD), a secretory process mediated by transport vesicles. "
09/01/2000 - "The eosinophil granule proteins are important mediators in allergic inflammation. "
03/01/1998 - "The findings suggest that eosinophil granule proteins may participate in tissue damage in acute phase of inflammation in OCP."
06/01/1997 - "It was concluded that signaling via adhesion molecules might play an important role in the pathogenesis of allergic inflammation through activation of eosinophils, such as through an increase in oxidative metabolism or degranulation of eosinophil granule proteins."
03/01/1997 - "There is mounting evidence that eosinophil granule proteins may cause tissue injury during allergic inflammation of the eye. "