Deep Brain Stimulation

Therapy for MOVEMENT DISORDERS, especially PARKINSON DISEASE, that applies electricity via stereotactic implantation of ELECTRODES in specific areas of the BRAIN such as the THALAMUS. The electrodes are attached to a neurostimulator placed subcutaneously.

Also Known As:

Networked: 4247 relevant articles (554 outcomes, 394 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Okun, Michael S: 112 articles (12/2015 - 01/2004)
2.	Lozano, Andres M: 103 articles (11/2015 - 01/2002)
3.	Foote, Kelly D: 90 articles (04/2015 - 01/2004)
4.	Aziz, Tipu Z: 66 articles (10/2015 - 01/2002)
5.	Moro, Elena: 58 articles (09/2015 - 01/2002)
6.	Limousin, Patricia: 56 articles (12/2015 - 03/2006)
7.	Zrinzo, Ludvic: 52 articles (12/2015 - 07/2007)
8.	Sturm, Volker: 52 articles (07/2015 - 01/2003)
9.	Volkmann, Jens: 51 articles (08/2015 - 01/2002)
10.	Deuschl, Günther: 47 articles (09/2015 - 01/2002)

Related Diseases

1.	Parkinson Disease (Parkinson's Disease) 12/01/2014 - "The functional state of Parkinson's disease patients with motor disabilities refractory to best medical treatment improved significantly after subthalamic nucleus deep brain stimulation. " 01/13/2014 - "Deep brain stimulation of the subthalamic nucleus, although highly effective for the treatment of motor impairment in Parkinson's disease (PD), can induce speech deterioration in a subgroup of patients. " 01/01/2014 - "Deep brain stimulation of the subthalamic nucleus (STN) is a highly effective treatment for motor symptoms of Parkinson's disease. " 01/01/2014 - "Deep brain stimulation of the subthalamic nuclei (STN-DBS) is an effective treatment for the most severe forms of Parkinson's disease (PD) and is intended to suppress these patients' motor symptoms. " 01/01/2013 - "Deep brain stimulation targeting the subthalamic nucleus or globus pallidus internus are highly effective for the symptomatic treatment of Parkinson's disease. "
2.	Dystonia (Limb Dystonia) 11/01/2013 - "Deep brain stimulation (DBS), specifically of the globus pallidus interna (GPi), has been shown to be extremely effective in primary generalized dystonia. " 07/01/2008 - "Pallidal deep brain stimulation (DBS) is currently the most effective treatment for advanced, medically refractory dystonia. " 10/15/2007 - "Deep brain stimulation (DBS) of the globus pallidus internus (GPi) is a highly effective treatment for idiopathic generalized dystonia, however less is known about the effect of GPi DBS on ICCD. " 06/01/2007 - "In recent years, deep brain stimulation (DBS) of globus pallidus internus (GPi) has emerged as an effective treatment for dystonia, particularly patients with primary generalized dystonia, where remarkable improvement may occur. " 11/01/2006 - "For example, generalized dystonia involving whole the body and resulting in bed-ridden state can be dramatically improved with stereotactic chronic deep brain stimulation of the globus pallidum interna. "
3.	Tremor (Tremors) 07/01/2014 - "Deep brain stimulation of globus pallidus internus, thalamus or subthalamic area led to a marked improvement of dystonic axial or appendicular tremors in most cases refractory to other treatments. " 05/01/2011 - "Deep brain stimulation is the most effective treatment for most tremors but is reserved for advanced cases." 08/01/2009 - "Fortunately, deep brain stimulation is effective for the most common and disabling tremor disorders. " 06/28/2005 - "Chronic deep brain stimulation (DBS) (Level C) and thalamotomy (Level C) are highly efficacious in reducing tremor. " 03/01/2015 - "Deep brain stimulation (DBS) has been proposed as an effective therapy for vocal tremor, but very few studies exist in the literature that comprehensively evaluate the efficacy of DBS for specifically addressing EVT. "
4.	Movement Disorders (Movement Disorder) 07/01/2014 - "Deep brain stimulation (DBS) is an implanted electrical device that modulates specific targets in the brain resulting in symptomatic improvement in a particular neurologic disease, most commonly a movement disorder. " 01/01/2006 - "Functional neurosurgery has benefited from these technologies, as deep brain stimulation surgery has become the standard of care for most cases of movement disorder surgery. " 07/01/2014 - "Deep brain stimulation (DBS) has proven remarkably safe and effective in the treatment of movement disorders. " 05/01/2004 - "Quantifying movement disorders is becoming crucially important in neurosurgery units to evaluate the efficacy of new therapeutic interventions such as deep brain stimulation. " 01/01/2014 - "High-frequency electrical stimulation of specific brain structures, known as deep brain stimulation (DBS), is an effective treatment for movement disorders, but mechanisms of action remain unclear. "
5.	Essential Tremor (Essential Tremors) 03/01/2005 - "Deep brain stimulation is the best option for patients with disabling, drug-resistant essential tremor. " 05/01/2014 - "Deep brain stimulation (DBS) has proven to be a safe and effective therapy for refractory essential tremor, but information regarding long-term outcomes is lacking. " 08/01/2014 - "Chronic deep brain stimulation of the nucleus ventralis intermedius is an effective treatment for individuals with medication-resistant essential tremor. " 09/11/2013 - "Although thalamic deep brain stimulation is an effective treatment for patients with essential tremor, little is known about its effect on cortical neural dynamics. " 01/01/2013 - "Parkinsonian and essential tremor can often be effectively treated by deep brain stimulation. "

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Related Therapies and Procedures

1.	Electrodes (Electrode)
2.	Pallidotomy
3.	Microelectrodes
4.	Vagus Nerve Stimulation
5.	Drug Therapy (Chemotherapy)