Abdominal Hernia (Abdominal Hernias)

A protrusion of abdominal structures through the retaining ABDOMINAL WALL. It involves two parts: an opening in the abdominal wall, and a hernia sac consisting of PERITONEUM and abdominal contents. Abdominal hernias include groin hernia (HERNIA, FEMORAL; HERNIA, INGUINAL) and VENTRAL HERNIA.

Also Known As:

Networked: 209 relevant articles (3 outcomes, 22 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Wounds and Injuries (Trauma)
2.	Hernia (Hernias)
3.	Infection
4.	Fat Necrosis
5.	Obesity

Experts

1.	Zieren, Jürgen: 3 articles (01/2004 - 01/2002)
2.	Lubowiecka, Izabela: 2 articles (01/2015 - 01/2013)
3.	Osadchyĭ, D M: 2 articles (09/2013 - 01/2012)
4.	Pascual, Gemma: 2 articles (12/2010 - 09/2008)
5.	Selber, Jesse C: 2 articles (09/2009 - 05/2006)
6.	Serletti, Joseph M: 2 articles (09/2009 - 05/2006)
7.	Neuss, Heiko: 2 articles (01/2004 - 04/2002)
8.	Paul, Marco: 2 articles (01/2004 - 01/2002)
9.	Maecker, Folkert: 2 articles (04/2002 - 01/2002)
10.	Müller, Jochen M: 2 articles (04/2002 - 01/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Abdominal Hernia:

1.	Polypropylenes (Polypropylene)IBA 05/01/2012 - "The polypropylene mesh surrounded by fibrous tissue was effective in the correction of induced abdominal hernias, with a lower degree of macroscopic adhesions when compared to polypropylene mesh." 04/01/2002 - "An animal (pig) trial was performed to ascertain whether a Trevira mesh offers any advantages over currently employed meshes like Prolene for abdominal hernia repair. " 02/01/1999 - "The purpose of this experimental animal study was to investigate whether mesh fixation is necessary in abdominal hernia repair using a polypropylene mesh in the sublay technique. " 06/01/2015 - "After 21 days, abdominal hernia developed was corrected as follows: 1) No mesh; 2) Polypropylene mesh; and, 3) Ultrapro(r) mesh. " 06/01/2015 - "Polypropylene mesh is commonly used in the treatment of abdominal hernia. "
2.	CollagenIBA 12/01/2010 - "Prior studies suggest impaired collagen metabolism involving the whole abdominal wall including the skin in patients with abdominal hernia. " 11/01/2013 - "Modification of collagen formation by mesenchymal stem cells isolated from human adipose tissue in culture and after autotransplantation for abdominal hernia plasty." 01/01/2009 - "Degradation of collagen by metalloproteinase 2 in patients with abdominal hernias." 01/01/2008 - "[Abdominal wall reconstruction with collagen membrane in an animal model of abdominal hernia. " 04/01/1995 - "[Plastic surgery in large abdominal hernias using collagen patches]."
3.	BariumIBA 06/01/1994 - "The imaging findings associated with internal abdominal hernia have been reported for plain radiography, barium studies, arteriography and computed tomography. " 12/01/1993 - "Most abdominal hernias can be diagnosed on the basis of findings on physical examination or plain films and barium studies. " 09/01/2009 - "Knowing the radiological features of various types of abdominal hernias on MDCT and barium-enhanced radiographs allows confident diagnosis of these pathologies." 03/01/1995 - "However, plain radiography, radiography performed after administration of barium, and computed tomography allow evaluation of suspected abdominal hernias and detection of those that are clinically occult. "
4.	Fibrin Tissue Adhesive (Fibrin Sealant)IBA 06/01/2007 - "Experimental comparison of type of Tissucol dilution and composite mesh (Parietex) for laparoscopic repair of groin and abdominal hernia: observational study conducted in a university laboratory." 08/01/1999 - "Effects of fibrin glue and growth factors released from platelets on abdominal hernia repair with a resorbable PGA mesh: experimental study."
5.	PolyestersIBA 07/01/2000 - "Biostability, inflammatory response, and healing characteristics of a fluoropassivated polyester-knit mesh in the repair of experimental abdominal hernias." 06/07/1997 - "Commercial polyester fabric repair of abdominal hernias and defects." 03/01/1969 - "[Evaluation of the use of polyester mesh in major abdominal hernia]." 07/01/2004 - "The synthetic implant meshes in clinical use for the treatment of abdominal hernias are generally made of polyester in France and of polypropylene in Germany. " 09/01/1990 - "A trial was undertaken of the usefulness in alloplasty of abdominal hernias of three synthetic materials--Polish polyester net Dallop, polypropylene net Marlex and Gore-tex prostheses of soft tissues. "
6.	AllodermIBA 06/01/2008 - "Early results in repair of abdominal hernia with AlloDerm appear to have a complication rate of 24%. " 06/01/2008 - "Results of AlloDerm use in abdominal hernia repair." 01/01/2008 - "Although Alloderm has been reported to be an effective biologic material for abdominal hernia reconstruction, we have noted significant laxity requiring secondary intervention." 02/01/2004 - "Acellular cadaveric dermis (AlloDerm): a new alternative for abdominal hernia repair." 07/01/2005 - "This study evaluates the repair of incisional and recurrent abdominal hernias with multilayered acellular dermal allograft (AlloDerm; LifeCell Corporation, Branchburg, NJ) and musculofascial separation. "
7.	diclofenac hydroxyethylpyrrolidine (DIEP)FDA Link 10/01/2010 - "Abdominal hernias occurred in three TRAM patients (2.9 percent) and in no DIEP patients, whereas abdominal bulges occurred in three TRAM patients (2.9 percent) and four DIEP patients (6.9 percent); these differences were not statistically significant. " 05/01/2004 - "Sensitivity analyses were performed by assuming that the probabilities of occurrence of hernia, abdominal bulging, total flap loss, operating room time, and hospital stay were identical with the DIEP and free TRAM techniques. " 08/01/2014 - "However, MS-TRAM showed a higher rate of abdominal hernias and a lower rate of fat necrosis than DIEP. " 08/01/2014 - "The results of the meta-analysis showed that patients with MS-TRAM had a higher rate of abdominal hernias (RR 2.354, 95 % CI 1.154-4.802, P = 0.019) and a lower rate of fat necrosis (RR 0.502, 95 % CI 0.347-0.727, P = 0.000) than patients with DIEP. " 09/01/2009 - "This study compared the risk of fat necrosis, partial flap loss, total flap loss, abdominal bulge, laxity, or weakness, and abdominal hernia after deep inferior epigastric perforator (DIEP) and free transverse rectus abdominis myocutaneous (TRAM) flap surgery for breast reconstruction. "
8.	Anti-Bacterial Agents (Antibiotics)IBA 12/01/2015 - "The loading of antibiotics to surgical meshes to deliver them locally in the abdominal hernia repair site can be one way to manage infections associated with surgical implants. " 04/01/2015 - "This study retrospectively examined the charts of patients who developed mesh-site infection following surgery for abdominal hernia repair to determine how effective conservative management in the form of antibiotics and wound management was on the resolution of infection and wound healing. " 09/01/2014 - "Eight of the 15 patients experienced a local complication; these included seroma(n=2), hematoma (n = 1), infection requiring debridement and antibiotics (n = 2), partial flap necrosis (n = 2) and abdominal hernia (n=1). "
9.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/01/2005 - "The aim of this study was to assess the production of VEGF and b-FGF in wound drainage fluid from patients undergoing incisional abdominal hernia repair. " 11/01/2003 - "We measured vascular endothelial growth factor (VEGF) levels in serum and early wound fluid following primary sutured and mesh repair of abdominal hernias. "
10.	Polyethylene Terephthalates (Polyethylene Terephthalate)IBA 01/01/2004 - "Introduction of polyethylene terephthalate mesh (KoSa hochfest) for abdominal hernia repair: an animal experimental study." 01/01/2002 - "The adhesion formation and stability of intraperitoneal abdominal hernia repairs with DualMesh (macroporous ePTFE mesh with a microporous component) and PolyesterComposite (the newly developed polyurethane-covered Dacron mesh) were compared in a rat model. "

Therapies and Procedures

1.	Prostheses and Implants (Prosthesis) 12/01/2014 - "The objective of the present study is to evaluate early and mid-term outcomes in the largest French series that included 43 consecutive complex abdominal hernias repaired with biological prostheses. " 02/01/2012 - "Evaluation of crosslinked and non-crosslinked biologic prostheses for abdominal hernia repair." 09/01/2011 - "The analysed modification of laparoscopic abdominal hernia repair does not create risk of internal organ interposition between the prosthesis and integuments and prevents mesh from being corrugated." 09/01/2011 - "[The assessment of modification of prosthesis fixation method on visceral interposition during laparoscopic abdominal hernia reconstruction]." 03/01/2011 - "A 32-year-old woman was treated for a large abdominal hernia by mesh prosthesis nine years after a traffic accident injury. "
2.	Continuous Ambulatory Peritoneal Dialysis (CAPD) 01/01/1994 - "The aim of this study was to find out whether prosthetic mesh repair of recurrent and large abdominal hernias in continuous ambulatory peritoneal dialysis (CAPD) patients is effective in maintaining them on CAPD. " 01/01/1986 - "Twenty-five percent of all CAPD patients reviewed in this study developed abdominal hernias. " 01/01/2000 - "In CAPD patients without obvious abdominal hernias, peritoneal scintigraphy at onset of dialysis discovered 17% positive cases. " 07/01/1999 - "[Abdominal hernia as risk for continuation of continuous ambulatory peritoneal dialysis: case report]." 07/01/1996 - "Continuous ambulatory peritoneal dialysis complicating with abdominal hernias in children."
3.	Transplants (Transplant) 01/01/2011 - "The crucial problem in surgery treatment of abdominal hernias is its recurrence, especially high in procedures performed without use of synthetic graft. " 07/01/2007 - "Medline and PubMed were searched for English or German publications using the following keywords: components separation technique (CST), Ramirez, da Silva, fascia lata, tensor fasciae latae, latissimus dorsi, rectus femoris, myocutaneous flap, ((auto)dermal) graft, dermoplasty, cutisplasty, hernia, abdominal wall defect, or combinations thereof. " 09/01/2006 - "There are promising, albeit limited, clinical data with short-term follow-up for only a few of the many biological tissue grafts that are being promoted currently for the repair of abdominal hernias. " 06/01/2006 - "The rationale for the use of grafts is to reinforce and strengthen pelvic organ repairs similar to the use of grafts to strengthen abdominal hernia repair." 01/01/2001 - "Synthetic grafts permit to repair any abdominal hernia regardless of it size and anatomic state of tissues, to expand indications for surgery in patients with concomitant diseases."
4.	Peritoneal Dialysis 01/01/2000 - "This study investigated the incidence of subclinical abdominal hernia in patients starting peritoneal dialysis (PD). " 01/01/2011 - "[Risk factors for abdominal hernias in patients undergoing peritoneal dialysis]." 01/01/2004 - "Natural history and outcome of incarcerated abdominal hernias in peritoneal dialysis patients." 08/01/1987 - "Abdominal hernias are noted with increasing frequency in association with peritoneal dialysis as this mode of dialysis becomes increasingly popular. " 01/01/2000 - "The patient remained on cycler therapy for approximately four months when the unrelated development of an abdominal hernia required termination of peritoneal dialysis and subsequent transfer to hemodialysis. "
5.	Mammaplasty (Breast Reconstruction) 08/01/1997 - "Abdominal hernias after breast reconstruction." 07/01/2008 - "To investigate the clinical application of TRAM-RPAS flap in the one-stage breast reconstruction for patients with breast cancer, and to discuss the method to reduce the incidence of abdominal hernia and abdominal bulging. " 06/01/1998 - "The records of all women who underwent either a bilateral or unilateral pedicled TRAM flap breast reconstruction through the Emory Clinic from 1987 to 1994 (n = 257) were retrospectively analyzed with respect to general, breast (fat necrosis, flap loss, and cellulitis), and abdominal (hernia, skin loss, and cellulitis) complications. " 01/01/2001 - "The authors report the successful repair of large lower abdominal hernia defects after transverse rectus abdominis muscle (TRAM) flap breast reconstruction in 11 patients using a technique of intraperitoneal application of synthetic polypropylene (Prolene) mesh anchored to the peritoneal surface of the abdominal wall tissues. " 09/01/2009 - "This study compared the risk of fat necrosis, partial flap loss, total flap loss, abdominal bulge, laxity, or weakness, and abdominal hernia after deep inferior epigastric perforator (DIEP) and free transverse rectus abdominis myocutaneous (TRAM) flap surgery for breast reconstruction. "