Donor Selection

The procedure established to evaluate the health status and risk factors of the potential DONORS of biological materials. Donors are selected based on the principles that their health will not be compromised in the process, and the donated materials, such as TISSUES or organs, are safe for reuse in the recipients.

Also Known As:

Networked: 587 relevant articles (55 outcomes, 31 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Chang, Ying-Jun: 5 articles (01/2021 - 04/2016)
2.	Huang, Xiao-Jun: 5 articles (01/2021 - 04/2016)
3.	Hsu, Katharine C: 5 articles (10/2020 - 11/2007)
4.	Busch, M P: 5 articles (06/2001 - 05/2000)
5.	Lentine, Krista L: 4 articles (01/2020 - 02/2016)
6.	Wang, Tao: 4 articles (01/2019 - 10/2010)
7.	Luban, Naomi L C: 4 articles (11/2017 - 07/2003)
8.	Busch, Michael P: 4 articles (01/2016 - 03/2006)
9.	Ness, Paul: 4 articles (10/2013 - 11/2007)
10.	Bertaina, Alice: 3 articles (01/2022 - 10/2014)

Related Diseases

1.	Infections 01/01/2010 - "Donor screening and laboratory testing, while highly effective in reducing risk, cannot eliminate all risk from known agents and must be developed de novo to address emerging infections. " 08/04/2007 - "Donor screening and testing have dramatically reduced infectious risks in the developed world, but infection remains a major hazard in developing countries, where 13 million units of blood are not tested for HIV or hepatitis viruses. " 09/01/1990 - "Modifications in donor screening and the introduction of laboratory testing of donated blood for anti-HIV-1 and anti-HTLV-I have resulted in a significant reduction in the risks of retroviral infections from blood transfusion. " 10/01/2010 - "Through more scrutiny in donor selection, improved serological test & reevaluation of infections routes in donor, infection reduction can be achieved." 09/01/2016 - "Special attention should be paid to criteria of donor selection, albeit positive results may be due to a previous infection in these donors. "
2.	Graft vs Host Disease (Graft-Versus-Host Disease) 01/01/2021 - "Advances in transplantation techniques, such as donor selection, conditioning regimen modification, and graft-versus-host disease prophylaxis, have successfully improved the outcomes of AML patients receiving haplo-SCT and extended the haploidentical transplant indictions for AML. " 01/01/2022 - "In this review, we summarized the current status of allo-HSCT for ALL, mainly focusing on transplant indications, donor selection, conditioning regimens, graft-versus-host disease prophylaxis, incorporation of targeted immunotherapy with allografting, and measurable residual disease-directed intervention for transplant outcome improvement. " 01/01/2022 - "Allogeneic HSCT is limited by donor selection, morbidity and mortality from transplant conditioning, graft-versus-host disease and graft rejection, whereas significant concerns regarding long-term safety, efficacy and cost limit the broad applicability of gene therapy. " 12/01/2021 - "The recommendations address indications, pretransplant patient evaluation, donor selection, stem cell sources, conditioning regimens, prophylaxis of rejection and graft versus host disease, and post-transplant follow-up." 12/01/2021 - "Further, recent advances in HCT preparative regimens, donor selection, graft manipulation, and graft-versus-host disease prophylaxis and treatment have resulted in fewer transplant-related morbidities and mortality and better survival outcomes. "
3.	Transfusion Reaction 07/23/1987 - "Patients and physicians need to understand that an absolutely safe blood supply is an unattainable goal, but that current approaches to donor selection and testing are highly effective in minimizing the risk of transfusion-transmitted infection." 07/20/2012 - "Despite screening blood donations with advanced technologies and improved donor screening, the risk of transfusion-transmitted infections persists. " 01/01/2002 - "Careful donor selection has reduced but not eliminated the risk of transfusion-transmitted infections. " 10/01/1999 - "Efficacy of donor screening for HTLV-I and the natural history of transfusion-transmitted infection." 01/01/2022 - "Blood transfusion involves several steps including appropriate donor selection, cross-matching, blood collection, and administration, as well as monitoring and handling of transfusion reactions. "
4.	Hepatitis 04/01/1998 - "Many factors share responsibility for this accomplishment; however, two stand above the rest: (i) improved donor selection and screening criteria, especially elimination of paid blood donations; and (ii) major advances in testing for viral hepatitis carriers. " 01/01/1965 - "Reduced incidence of hepatitis in blood-recipients by means of donor-screening by electro-dermatography." 06/01/2001 - "Studies of patients with post-transfusion non-A, non-B hepatitis and their implicated donors were critical to the discovery of hepatitis C virus (HCV) and to the development and progressive enhancement of HCV immunoassays for donor screening and diagnostic applications. " 01/01/2020 - "In response to this rapidly changing landscape in the United States, experts in the field of viral hepatitis and liver and kidney transplantation convened a meeting to review current data on liver and kidney recipient selection and developed consensus opinions related specifically to recipient and donor selection of HCV viremic liver and kidney allografts." 01/01/2003 - "Novel therapeutic options seem to be promising but preventing measures including donor screening, immunization against hepatitis A virus (HAV) and hepatitis B virus (HBV), universal use of disposable syringes and implementation of better hygienic conditions play a major role in the control of viral hepatitis. "
5.	Communicable Diseases (Infectious Diseases) 03/01/2000 - "Careful donor screening and infectious disease marker testing have significantly reduced the incidence of transfusion-transmitted diseases and improved the safety of the blood supply. " 04/01/2016 - "Extensive donor screening together with improved infectious disease testing has led to a minimization of risks for transfusion recipients. " 05/01/2011 - "Advances in donor selection, infectious disease testing of donated blood, use of leukocyte reduction and irradiation of blood in defined situations have improved the safety of the blood supply in terms of infection transmission. " 06/01/1996 - "Donor screening and improved infectious disease testing of units for transfusion have contributed to the decreased risk of transfusion-transmitted diseases. " 11/01/2015 - "Current studies have demonstrated minimal adverse effects, with no reports of transmission of infectious diseases; however, the optimal delivery method, sample preparation, and donor selection remain unclear. "

Related Drugs and Biologics

1.	N-acetyltalosaminuronic acid (NAT)
2.	Nucleic Acids
3.	Hepatitis B Surface Antigens (HBsAg)
4.	RNA (Ribonucleic Acid)
5.	Blood Coagulation Factors (Coagulation Factor)
6.	Antibodies
7.	HLA Antigens (Human Leukocyte Antigens)
8.	dibenzyldithiocarbamate (DBDC)
9.	Antigens
10.	Hepatitis B Core Antigens

Related Therapies and Procedures

1.	Transplantation
2.	Therapeutics
3.	Liver Transplantation
4.	Blood Transfusion (Blood Transfusions)
5.	Bone Marrow Transplantation (Transplantation, Bone Marrow)