Anabolic Agents

06/01/2023 - "On serial follow-up, the anterior body height of the fractured vertebra improved significantly, demonstrating the importance of osteoporosis treatment using anabolic agents. "
03/13/1999 - "The conjunction of favorable anabolic effects demonstrated in animal models, concerning both bone density and mechanical properties, and early studies in humans, provide converging arguments similar to those observed in preclinical investigations, suggest that PTH could be a promising treatment for osteoporosis."
01/01/2018 - "Anabolic agents have been shown to improve bone mass and decrease fracture risk in osteoporosis patients by directly stimulating osteoblasts to produce new bone. "
07/20/2007 - "Currently, anabolic agents that promote bone formation are increasingly used as a new treatment for osteoporosis. "
04/20/2018 - "Therefore, it is questionable if TBS and HSA are really helpful in monitoring bone quality and in defining reduction of individual fragility fracture risk during osteoporosis treatment with bone anabolic agents."

04/01/2014 - "Patients 0 to 18 years old with burns covering ≥ 30% of the total body surface area and not randomized to receive anabolic agents were included in this study. "
10/01/2014 - "We also review the commonly used anabolic agents clinically in the care of burn patients. "
04/01/1998 - "The addition of anabolic agents in burn care and nutrition may be of importance. "
02/01/2016 - "Recent research evaluating the application of anabolic agents and immune-enhance formula for severe burns therapy has generated significant controversy. "
09/01/1999 - "Anabolic agents, such as recombinant human growth hormone (rhGH), have been used effectively to ameliorate the catabolic response to burn injury and to improve wound-healing. "

03/01/2004 - "The anabolic effects of AC-100 may be beneficial for bone diseases associated with decreased bone formation."
02/01/1982 - "It has been suggested that small doses of PTH could exert an anabolic effect on bone and could be beneficial in the management of bone diseases secondary to low bone formation. "
07/01/2013 - "Our study clarifies that the anabolic effects in the treatment of MM-induced bone disease are associated with promoting the differentiation of bone marrow stromal cells (BMSC) and inhibiting the apoptosis of active osteoblasts, while promoting the differentiation of osteoblast precursors is instead suggested to be associated with the anti-catabolic effects. "
04/19/2023 - "These findings demonstrate the therapeutic value of bone anabolic agents to treat diabetes-induced bone disease and suggest the need for revisiting the approaches for the treatment of bone fragility in diabetes."
01/01/2023 - "As a promising bone-targeting drug delivery system, our system may be extrapolated to clinical applications of other bone anabolic agents for different bone diseases."

01/01/2018 - "It was not possible to establish a direct relationship between habits and meniscal and ligamentous injuries, despite the finding that patients with ACL-associated lesions were more frequently smokers, and that patients with isolated meniscal injuries used more artificial anabolic agents. "
02/01/2013 - "Using a novel rabbit model of cancellous bone loading, we examined two specific questions regarding bone formation at the bone-implant interface: (1) does the administration of intermittent PTH, a potent anabolic agent, and mechanical loading individually and combined enhance the peri-implant cancellous bone volume fraction; and, (2) does surgical trauma enhance the anabolic effect of PTH on peri-implant bone volume fraction. "
01/01/2018 - "There were no significant findings correlating smoking, alcohol abuse and artificial anabolic agents with the presence of injuries. "
01/01/1999 - "Involuntary weight loss and the nonhealing wound: the role of anabolic agents."
06/01/1998 - "Anabolic agents in trauma and sepsis: repleting body mass and function."

01/01/2005 - "Our data suggest that the anabolic effect of GH on trabecular and cortical bone remains demonstrable after remission of acromegaly, although it may not be maintained at cortical sites in the long term. "
10/01/2023 - "Despite GH having anabolic effects on bone growth and renewal, the risk of vertebral fractures is paradoxically increased in acromegaly. "
01/01/2006 - "An anabolic effect of GH during active acromegaly was present in the proximal femur only in men. "
01/01/2005 - "Long-term maintenance of the anabolic effects of GH on the skeleton in successfully treated patients with acromegaly."
01/01/2009 - "BMD is generally increased in acromegaly, though the anabolic effect of GH excess on bone is reduced, if not negated, by the presence of hypogonadism, particularly with regard to the trabecular compartment. "