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Diffuse Scleroderma (Progressive Systemic Sclerosis)

A rapid onset form of SYSTEMIC SCLERODERMA with progressive widespread SKIN thickening over the arms, the legs and the trunk, resulting in stiffness and disability.
Also Known As:
Progressive Systemic Sclerosis; Scleroderma, Diffuse; Diffuse Cutaneous Systemic Sclerosis; Diffuse Systemic Sclerosis; Scleroderma, Progressive; Sclerosis, Progressive Systemic; Sudden Onset Scleroderma; Diffuse Systemic Scleroses; Progressive Scleroderma; Scleroderma, Sudden Onset; Sclerodermas, Sudden Onset; Scleroses, Diffuse Systemic; Sclerosis, Diffuse Systemic; Sudden Onset Sclerodermas; Systemic Scleroses, Diffuse; Systemic Sclerosis, Diffuse; Systemic Sclerosis, Progressive
Networked: 1164 relevant articles (71 outcomes, 122 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Rheumatoid Arthritis
2. Interstitial Lung Diseases (Interstitial Lung Disease)
3. Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous)
4. Fibrosis (Cirrhosis)
5. Systemic Scleroderma (Systemic Sclerosis)

Experts

1. Denton, Christopher P: 18 articles (01/2022 - 01/2007)
2. Khanna, Dinesh: 16 articles (11/2021 - 01/2007)
3. Allanore, Yannick: 16 articles (09/2021 - 06/2004)
4. Furst, Daniel E: 16 articles (07/2021 - 11/2002)
5. Whitfield, Michael L: 11 articles (12/2020 - 10/2003)
6. Lafyatis, Robert: 10 articles (09/2021 - 02/2009)
7. Distler, Oliver: 10 articles (07/2021 - 01/2017)
8. Gordon, Jessica K: 10 articles (12/2020 - 11/2010)
9. van Laar, Jacob M: 9 articles (01/2022 - 01/2010)
10. Furst, D E: 9 articles (11/2014 - 06/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Diffuse Scleroderma:
1. Cyclophosphamide (Cytoxan)FDA LinkGeneric
2. Rituximab (Mabthera)FDA Link
3. Penicillamine (Cuprimine)FDA Link
4. Abatacept (Orencia)FDA Link
5. Imatinib Mesylate (Gleevec)FDA Link
6. Mycophenolic Acid (Cellcept)FDA LinkGeneric
7. AcidsIBA
8. Methotrexate (Mexate)FDA LinkGeneric
9. RelaxinIBA
10. ametantrone (HAQ)IBA

Therapies and Procedures

1. Therapeutics
2. Stem Cell Transplantation
3. Hematopoietic Stem Cell Transplantation
4. Transplantation
5. Plasma Exchange