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Corrinoids

Cyclic TETRAPYRROLES based on the corrin skeleton.

Networked: 9 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Gruner, T M: 2 articles (08/2006 - 05/2005)
2.	Kelly, R J: 2 articles (08/2006 - 05/2005)
3.	Sykes, A R: 2 articles (08/2006 - 05/2005)
4.	Alexeev, Erica E: 1 article (01/2019)
5.	Battista, Kayla D: 1 article (01/2019)
6.	Colgan, Sean P: 1 article (01/2019)
7.	Eric L, Campbell: 1 article (01/2019)
8.	Farb, Linda: 1 article (01/2019)
9.	Frank, Daniel N: 1 article (01/2019)
10.	Kelly, Caleb J: 1 article (01/2019)

Related Diseases

1.	Pernicious Anemia 03/01/1988 - "These data support that: (a) holo TC II is sharply depleted in untreated B12 deficiency; (b) normally, the only Cor on TC II are cobalamins; (c) in treated pernicious anemia, TC II appears to also bind non-cobalamin corrinoids; (d) continued malabsorption of vitamin B12 may result in reduced B12 on TC II within a month after the last parenteral therapy with 1000 micrograms of cyanocobalamin, and (e) TC II UBBC rises as B12 deficiency is developing. " 03/01/1988 - "We measured corrinoids (Cor) and cobalamins (Cbl) on transcobalamins I and III (TC I + III) and on TC II. We also measured the unsaturated B12 binding capacities of transcobalamin I and III and TC II in serum from patients with B12 deficiency (N = 5) (with or without concurrent folate deficiency), with pernicious anemia in remission (N = 7) (1 month after therapy), and in several control groups including healthy volunteers (N = 6), hematologically normal elderly hospitalized patients (N = 5), and non-B12 nonfolate deficient anemic elderly hospitalized volunteers (N = 5). "
2.	Colitis 01/01/2019 - "The aim of this study was to determine if oral B12 supplementation in mice alters 1) the concentration of B12 and related corrinoids in the distal gut, 2) the fecal microbiome, 3) short chain fatty acids (SCFA), and 4) susceptibility to experimental colitis. "
3.	Scrapie 05/01/2005 - "Corrinoids were extracted with a sodium acetate buffer, separated by HPLC and quantified by RIDA. " 05/01/2005 - "A method has been developed using a combination of high-performance liquid chromatography (HPLC) and a radioisotope dilution assay (RIDA) to routinely estimate the distribution of corrinoids (the cobalamins hydroxocobalamin, methylcobalamin and 5'-deoxyadenosylcobalamin, and cobalamin analogues) in liver, plasma, milk, intestinal fluid and faeces. " 08/01/2006 - "Corrinoids from various ovine tissue samples (liver, blood, small intestinal fluid and faeces) were analysed using a combination of high-performance liquid chromatography (HPLC) and a radioisotope dilution assay (RIDA) to estimate the distribution of corrinoids--the cobalamins hydroxocobalamin (OH-cbl), methylcobalamin (me-cbl) and 5'-deoxyadenosylcobalamin (ado-cbl), and cobalamin analogues--in these tissues. "
4.	Fibrosis (Cirrhosis) 01/01/1997 - "Plasma cobalamin (p < 0.005), total corrinoids (p < 0.005) and their analogs (p < 0.05) were all significantly elevated in the cirrhosis patients. " 01/01/1988 - "In the absence of significant hepatic cytolysis, the enhanced level of seric corrinoids in cirrhosis could be partly explained by a competitive inhibition of the liver uptake of haptocorrin by circulating asialoglycoproteins, including IgA."
5.	Vitamin B 12 Deficiency (Vitamin B12 Deficiency) 03/01/1988 - "Preferential depletion of corrinoids on transcobalamin II (i.e., sharply reduced holo transcobalamin II (TC II)) occurs early in vitamin B12 deficiency. "

Related Drugs and Biologics

1.	Vitamin B 12 (Cyanocobalamin)
2.	Transcobalamins (Transcobalamin II)
3.	Folic Acid (Vitamin M)
4.	Volatile Fatty Acids
5.	Radioisotopes (Radionuclides)
6.	Hydroxocobalamin
7.	mecobalamin (methylcobalamin)
8.	Sodium Acetate (Sodium Acetate, Anhydrous)
9.	Proteins (Proteins, Gene)
10.	Immunoglobulin A (IgA)

Related Therapies and Procedures

1.	Therapeutics