Continuous Positive Airway Pressure

A technique of respiratory therapy, in either spontaneously breathing or mechanically ventilated patients, in which airway pressure is maintained above atmospheric pressure throughout the respiratory cycle by pressurization of the ventilatory circuit. (On-Line Medical Dictionary [Internet]. Newcastle upon Tyne(UK): The University Dept. of Medical Oncology: The CancerWEB Project; c1997-2003 [cited 2003 Apr 17]. Available from: http://cancerweb.ncl.ac.uk/omd/)

Also Known As:

Networked: 3024 relevant articles (321 outcomes, 440 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Malhotra, Atul: 20 articles (09/2015 - 07/2002)
2.	Weaver, Terri E: 18 articles (02/2015 - 09/2003)
3.	Grunstein, Ronald R: 17 articles (10/2015 - 10/2004)
4.	Bradley, T Douglas: 15 articles (07/2015 - 03/2003)
5.	Floras, John S: 13 articles (09/2015 - 03/2003)
6.	Morgenthaler, Timothy I: 13 articles (05/2014 - 09/2006)
7.	Ancoli-Israel, Sonia: 13 articles (01/2014 - 01/2003)
8.	Guilleminault, Christian: 13 articles (01/2014 - 01/2004)
9.	White, David P: 12 articles (11/2013 - 07/2002)
10.	Dimsdale, Joel E: 12 articles (01/2013 - 12/2002)

Related Diseases

1.	Obstructive Sleep Apnea 08/15/2013 - "Continuous positive airway pressure is the most common and effective treatment for obstructive sleep apnea. " 07/01/2013 - "Despite the severity of obstructive sleep apnea in the propositus, the administration of continuous positive airway pressure was highly effective in alleviating his symptoms. " 12/01/2011 - "Continuous positive airway pressure (CPAP) is a highly efficacious treatment for obstructive sleep apnea (OSA) but adherence to the treatment limits its overall effectiveness across all age groups of patients. " 07/01/2010 - "Application of continuous positive airway pressure (CPAP) is effective in most of the patients and attenuates cardiodepressive hemodynamic effects of obstructive sleep apnea." 01/01/2009 - "Continuous positive airway pressure (CPAP) applied via a tight-fitting mask is the most effective treatment for obstructive sleep apnea (OSA) and has potential to improve the cardiovascular prognosis in such patients. "
2.	Sleep Apnea Syndromes (Sleep Apnea) 09/01/1999 - "Previous studies on continuous positive airway pressure (CPAP) treatment usually reported significant improvement in mood symptoms in patients with sleep apnea, but most of them did not consider the placebo effect of CPAP. " 03/01/1992 - "Continuous positive airway pressure (CPAP) was the treatment most often used by severe sleep apnea patients, and this improved daytime alertness in 84% of the patients. " 10/01/1993 - "Continuous positive airway pressure (CPAP) has proven to be a safe, effective treatment for sleep apnea patients. " 12/01/1997 - "We demonstrated in a previous study that excessive daytime sleepiness (EDS) in patients who have sleep apnea/hypopnea syndrome (SAHS) and are undergoing continuous positive airway pressure (CPAP) treatment improved differently in two groups of patients: in group I, multiple sleep latency tests (MSLT) were normalized after 50 days of treatment (individual value > 10 minutes), whereas they remained low (individual value < 10 minutes) in group II, with a significant difference between groups. " 03/01/2000 - "Mean reported educational level was grade 12, and mean reading level was between grade 7 and 8. Using video significantly improved only two areas of knowledge for low-level (below grade 8) readers: defining sleep apnea (66% vs 43%) and identifying what continuous positive airway pressure (CPAP) does for the patient (94% vs 78%). "
3.	Apnea 09/01/1995 - "Successful treatment of apnea by nasal continuous positive airway pressure dramatically reduced the movements during sleep (from 88.2 to 1.9 per hour). " 01/01/1983 - "Application of nasal continuous positive airway pressure through a modified nasal nitrous mask using a ball-valve resistor resulted in reduction of occlusive apnea to 1.17 episodes per hour of sleep and marked improvement in the quality of sleep." 01/01/2013 - "Clinicaltrials.gov: NCT01289392 RESULTS: After treatment with continuous positive airway pressure or an oral appliance, the patients presented with a significant reduction in the apnea-hypopnea index. " 10/01/2013 - "Continuous positive airway pressure is effective in the reduction of the occurrence of apneas. " 09/01/2013 - "Continuous positive airway pressure (CPAP) is effective in reducing the occurrence of apneas. "
4.	Heart Failure 01/01/2002 - "On the other hand, recent studies indicate that successful treatment of either type of SA with continuous positive airway pressure in patients with CHF results in objective and subjective improvement in the severity of heart failure increases in left ventricular ejection fraction, and reductions in sympathetic nervous system activity. " 11/01/1998 - "Efficacy of nasal continuous positive airway pressure therapy in chronic heart failure: importance of underlying cardiac rhythm." 12/01/1996 - "Nasal continuous positive airway pressure (CPAP) reduces the work of breathing in congestive cardiac failure (CCF) during short-term application, and chronic therapy has been reported to improve left ventricular function and sleep quality. " 12/01/2012 - "Recent studies have reported the clinical usefulness of positive airway pressure ventilation therapy with various kinds of pressure support compared with simple continuous positive airway pressure (CPAP) for heart failure patients. " 11/01/2009 - "Following the Canadian Continuous Positive Airway Pressure for Patients with Central Sleep Apnoea and Heart Failure trial, further SDB intervention studies have been reported using adaptive servo-ventilation. "
5.	Hypertension (High Blood Pressure) 10/01/2007 - "Therapy with continuous positive airway pressure (CPAP) has been associated with significant benefits to cardiovascular morbidity and mortality, both in short-term studies addressing specific aspects of morbidity, such as hypertension, and more recently in long-term studies that have evaluated major outcomes of cardiovascular morbidity and mortality. " 12/01/1992 - "Hypertension was eliminated in a subgroup of our patients treated with tracheostomy or nasal continuous positive airway pressure (CPAP), although the total group had no statistically significant blood pressure differences. " 08/01/2015 - "Since its inception in the early 1980's, continuous positive airway pressure (CPAP) has emerged as the major treatment of OSA, and it has been shown to improve sleepiness, hypertension, and a number of cardiovascular indices. " 01/01/2014 - "Several drugs are used to control hypertension, but the only consistently effective treatment of OSA is continuous positive airway pressure. " 05/01/2006 - "Furthermore, treatment with continuous positive airway pressure may improve quality of life and may help to manage hypertension in these patients. "

Related Drugs and Biologics

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3.	Insulin (Novolin)
4.	SAS
5.	Glucose (Dextrose)
6.	heliox
7.	sildenafil (Viagra)
8.	Diuretics
9.	salicylhydroxamic acid (SHAM)
10.	Leptin

Related Therapies and Procedures

1.	Continuous Positive Airway Pressure
2.	Artificial Respiration (Mechanical Ventilation)
3.	Tracheostomy
4.	Intermittent Positive-Pressure Ventilation
5.	Aftercare (After-Treatment)