Peptide Nanotubes

NANOTUBES formed from cyclic peptides (PEPTIDES, CYCLIC). Alternating D and L linkages create planar rings that self assemble by stacking into nanotubes. They can form pores through CELL MEMBRANE causing damage to cells.

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Networked: 7 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Hu, Xianli: 2 articles (12/2019 - 01/2019)
2.	Lai, Yi: 2 articles (12/2019 - 01/2019)
3.	Lei, Li: 2 articles (12/2019 - 01/2019)
4.	Xu, Zhiai: 2 articles (12/2019 - 01/2019)
5.	Yu, Haijun: 2 articles (12/2019 - 01/2019)
6.	Zhang, Wen: 2 articles (12/2019 - 01/2019)
7.	Dong, Liang: 1 article (12/2019)
8.	Li, Lingling: 1 article (12/2019)
9.	Hou, Bo: 1 article (01/2019)
10.	Tian, Yang: 1 article (01/2019)

Related Diseases

1.	Tissue Adhesions 12/01/2019 - "1D peptide nanostructures (i.e., peptide nanotubes, PNTs) exhibit tunable chemo-physical properties and functions such as improved tissue adhesion, increased cellular uptake, and elongated blood circulation. "
2.	Neoplasms (Cancer) 12/01/2019 - "Peptide Nanotube-Templated Biomineralization of Cu2-x S Nanoparticles for Combination Treatment of Metastatic Tumor." 01/01/2019 - "The results highlight the promising potential of the multivalent peptide nanotubes for active tumor targeting and imaging-guided cancer therapy." 07/17/2018 - "The barrel-structured DNA nanotube-peptide was successfully applied as a codrug-delivery system for targeting cancer therapy. " 07/17/2018 - "A DNA Nanotube-Peptide Biocomplex for mRNA Detection and Its Application in Cancer Diagnosis and Targeted Therapy." 02/21/2013 - "Detection of cancer cells using a peptide nanotube-folic acid modified graphene electrode."
3.	Melanoma (Melanoma, Malignant) 01/01/2019 - "Bioinspired Multivalent Peptide Nanotubes for Sialic Acid Targeting and Imaging-Guided Treatment of Metastatic Melanoma." 01/01/2023 - "Peptide nanotube loaded with a STING agonist, c-di-GMP, enhance cancer immunotherapy against melanoma."
4.	Infections 01/01/2018 - "Self-assembling diphenylalanine peptide nanotubes selectively eradicate bacterial biofilm infection."
5.	Uterine Cervical Neoplasms (Cancer of the Cervix) 02/21/2013 - "Cyclic voltammograms in the presence of [Fe(CN)(6)](3-/4-) as a redox species demonstrated that the binding of the folate receptor from human cervical cancer cells to the peptide nanotube-folic acid modified electrode lowered the electron transfer resulting in a decrease in the measured current. " 02/21/2013 - "This article describes the preparation of a graphene electrode modified with a new conjugate of peptide nanotubes and folic acid for the selective detection of human cervical cancer cells over-expressing folate receptors. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	A-Form DNA (A-DNA)
3.	N-Acetylneuraminic Acid (Sialic Acid)
4.	Messenger RNA (mRNA)
5.	Graphite
6.	Folic Acid (Vitamin M)
7.	DNA (Deoxyribonucleic Acid)
8.	Amyloid (Amyloid Fibrils)
9.	bis(3',5')-cyclic diguanylic acid
10.	diphenylalanine

Related Therapies and Procedures

1.	Therapeutics
2.	Immunotherapy
3.	Electrodes (Electrode)