Anti-Retroviral Agents (Antiretroviral Agents)

01/15/2009 - "The recent availability of new antiretroviral agents for the treatment of human immunodeficiency virus (HIV) infection has increased treatment options and has improved the durability, tolerability, and long-term efficacy of antiretroviral therapy, even among patients with extensive treatment experience and high levels of drug resistance. "
07/01/2013 - "There is increasing evidence that the use of antiretroviral agents (ARVs) can be a safe and effective means of preventing HIV infection. "
09/01/2003 - "Pharmacokinetic data obtained from children who have human immunodeficiency virus (HIV) infection are essential for the safe and effective use of antiretroviral agents in pediatric populations. "
12/01/1994 - "Because the efficacy of currently approved antiretroviral agents used as prolonged monotherapy is limited, there is an urgent need for alternative agents for the treatment of HIV infection. "
07/01/2009 - "The improved efficacy and safety of antiretroviral agents have fundamentally changed the face of HIV infection. "

11/01/1989 - "In addition to mass screening of SRV infection in macaque colonies, the AC assay also will be valuable for monitoring the efficacy of antiretroviral agents against SRV in vitro and in vivo."
01/01/1997 - "Despite the continued increase in the number of HIV-1-infected children, there is optimism that with the prospective identification of HIV-1-infected pregnant women, the incidence of infection can be diminished through prevention of mother-to-child transmission both by use of antiretroviral agents as well as by improved obstetrical management. "
11/01/2002 - "The efficacy of antiretroviral agents approved for the treatment of HIV-1 infection is limited by the virus's ability to develop resistance. "
12/01/2001 - "Viral resistance to antiretroviral agents may limit the efficacy of current treatment regimens for HIV-1 infection. "
10/01/2015 - "TAF is currently in phase 3 clinical studies for the treatment of HIV-1 infection, in combination with other antiretroviral agents. "

07/12/1997 - "Inclusion of women in clinical trials of antiretroviral agents for HIV/AIDS during pregnancy."
10/01/1990 - "Additional trials of maintenance therapy in patients with advanced AIDS-KS combining antiretroviral agents are in progress."
07/01/2012 - "Independent advisory committees of the President's Emergency Plan for AIDS Relief (PEPFAR) and the World Health Organization (WHO) have since issued analyses that set the stage for broader use of antiretroviral agents in treatment and prevention. "
03/01/2012 - "One hundred seventy HIV/AIDS patients with ≥2 antiretroviral agents were identified from the MEPS database, of which 53% (n=92) were on FXD formulation. "
01/01/2012 - "The rising pandemic of HIV and AIDS and high toxicity associated with anti-retroviral use are major factors that have compelled research to explore traditional herbal medicines as potential alternatives or supplements to anti-retroviral agents. "

01/01/1997 - "The potential for improved renal survival of patients with HIV-associated nephropathy has become more realistic with the development and use of antiretroviral agents, as well as studies on the role of immunosuppression and ACE inhibition in this population. "
04/01/2013 - "With the widespread use of combination antiretroviral agents, the incidence of HIV-associated nephropathy has decreased. "
11/01/2008 - "Accurate markers of glomerular filtration rate in human immunodeficiency virus (HIV)-infected persons would be useful for early diagnosis of HIV-associated nephropathy and other glomerular diseases, and for identifying patients at high risk for subsequent declines in kidney function who also may develop cardiovascular disease or renal complications from antiretroviral agents or other therapies. "
01/01/1998 - "The potential for improved renal survival of patients with HIV-associated nephropathy ahs become more realistic with the development and the use of antiretroviral agents, as well as studies on the role of immunosuppression and Angiotensin Converting Enzyme (ACE) inhibition in this population."
04/01/2001 - "A Medline search was performed using the key words "HIV," "nephropathy," "renal," and "kidney." A further search was performed for each of the currently licensed antiretroviral agents linked to key words "renal" or "kidney" and also using the MeSH heading "pharmacokinetics." HIV associated nephropathy is a common complication of HIV in black African and Afro-Caribbean patients and presents with progressive renal failure and heavy proteinuria. "

06/01/1999 - "Combinations of new antiretroviral agents have been shown to be effective in prolonging the life of infected individuals, and chemoprophylactic regimens have been useful in preventing opportunistic infections. "
01/01/2013 - "HIV infected patients are frequently exposed to anaemia, due to antiretroviral agents and/or prophylactic treatment of opportunistic infections. "
10/01/2003 - "The contemporary treatment of the child infected with human immunodeficiency virus (HIV) unavoidably requires combination therapy with antiretroviral agents and may include additional drugs for the prevention and treatment of opportunistic infections or other disease states. "
10/01/2002 - "Complex drug interactions involving antiretroviral agents and drugs for the management of opportunistic infections demand the monitoring of plasma drug concentrations to prevent treatment failure. "
03/01/1999 - "Several new antiretroviral agents were discussed at the 6th Conference on Retroviruses and Opportunistic Infections. "