Concatenated DNA

Head to tail array of covalently joined DNA sequences generated by concatenation. Concatenated DNA is attached end to end in contrast to CATENATED DNA which is attached loop to loop.

Also Known As:

DNA, Concatenated; DNA, Concatemers

Networked: 6 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleic Acids: 11752
  - DNA: 145982
    - Concatenated DNA: 6
Chemical Phenomena
- Biochemical Phenomena
  - Molecular Structure
    - Molecular Conformation
      - Nucleic Acid Conformation
        Concatenated DNA: 6
Genetic Phenomena
- Genetic Structures
  - Nucleic Acid Conformation
    - Concatenated DNA: 6

Experts

1.	Deng, Zhangshuang: 1 article (05/2022)
2.	Kang, Nana: 1 article (05/2022)
3.	Liu, Sijia: 1 article (05/2022)
4.	Ran, Jiabing: 1 article (05/2022)
5.	Wang, Fuan: 1 article (05/2022)
6.	Wang, Huimin: 1 article (05/2022)
7.	Weng, Benrui: 1 article (05/2022)
8.	Yang, Changying: 1 article (05/2022)
9.	Yang, Huiran: 1 article (05/2022)
10.	Akagi, Keiko: 1 article (02/2014)

Related Diseases

1.	Neoplasms (Cancer) 05/15/2022 - "The acid-improved DNAzyme-based concatenated DNA circuit is promising to expand the application of chemiluminescence assay and provide a valuable strategy for early diagnosis and prognosis of cancer."
2.	Infections 05/31/2002 - "However, whereas DNA concatemers that accumulate in prohead and terminase defective phage T4 infections could be packaged in vitro to approximately 10% wild-type efficiency, 55am33am defective concatemeric DNA was packaged at least 100-fold less efficiently. " 08/01/1996 - "The lytic replication cycle of herpesviruses can be divided into the following three steps: (i) circularization, in which, after infection, the termini of the linear double-stranded viral genome are fused; (ii) replication, in which the circular DNA serves as template for DNA replication, which generates large DNA concatemers; and (iii) maturation, in which the concatemeric viral DNA is processed into unit-length genomes, which are packaged into capsids. " 05/01/1995 - "After infection of host cells, the EBV DNA circularizes via the TRs by an unknown mechanism, and replication of the viral DNA during the lytic phase of the EBV life cycle leads to large DNA concatemers which need to be cleaved into virion DNA units, eventually. "
3.	Carcinogenesis 02/01/2014 - "We present a model of "looping" by which HPV integrant-mediated DNA replication and recombination may result in viral-host DNA concatemers, frequently disrupting genes involved in oncogenesis and amplifying HPV oncogenes E6 and E7. "
4.	Relapsing Fever 12/01/2009 - "All loci and the concatenated DNA sequence of 3,289 bases identified the Carios bacterium as a relapsing fever spirochete most closely related to, but distinct from, Borrelia turicatae. "

Related Drugs and Biologics

1.	Catalytic DNA (Deoxyribozyme)
2.	Acids
3.	Viral DNA
4.	DNA (Deoxyribonucleic Acid)
5.	Circular DNA
6.	terminase