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Ductal Carcinoma

Malignant neoplasms involving the ductal systems of any of a number of organs, such as the MAMMARY GLANDS, the PANCREAS, the PROSTATE, or the LACRIMAL GLAND.
Also Known As:
Carcinoma, Ductal; Carcinomas, Ductal; Ductal Carcinomas
Networked: 1842 relevant articles (18 outcomes, 221 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Carcinoma (Carcinomatosis)
3. Noninfiltrating Intraductal Carcinoma (DCIS)
4. Hyperplasia
5. B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)

Experts

1. Sasano, Hironobu: 14 articles (11/2014 - 02/2004)
2. Hasebe, Takahiro: 12 articles (09/2013 - 01/2004)
3. Li, Christopher I: 11 articles (09/2015 - 03/2003)
4. Ruibal, A: 11 articles (11/2012 - 06/2000)
5. Sakurai, Kenichi: 10 articles (11/2014 - 11/2007)
6. Amano, Sadao: 10 articles (11/2014 - 11/2007)
7. Enomoto, Katsuhisa: 10 articles (11/2014 - 11/2007)
8. Iwasaki, Motoki: 10 articles (09/2013 - 02/2007)
9. Daling, Janet R: 10 articles (02/2011 - 08/2002)
10. Reis-Filho, Jorge S: 9 articles (12/2014 - 08/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Ductal Carcinoma:
1. DNA (Deoxyribonucleic Acid)IBA
2. MucinsIBA
3. Cadherins (E-Cadherin)IBA
4. Keratins (Keratin)IBA
5. VimentinIBA
6. Carbon DioxideIBA
7. Fluorouracil (Carac)FDA LinkGeneric
8. Keratin-5 (Keratin 5)IBA
09/01/2000 - "In contrast, neoplastic epithelial cells in atypical ductal and lobular hyperplasias (ADH and ALH) lacked such an expression, whereas in ductal in-situ carcinomas (DCIS) and in infiltrating ductal carcinomas 3.7% and 7.7%, of the cases respectively, showed positive immunostaining for CK 5/6. Immunophenotyping of keratin 5/6 expression can be helpful in the diagnosis of atypical hyperplasias and in-situ carcinomas of the breast. "
01/01/2007 - "P-cadherin and cytokeratin 5: useful adjunct markers to distinguish basal-like ductal carcinomas in situ."
01/01/2012 - "We performed immunohistochemical analyses of the estrogen receptor, progesterone receptor, cytokeratin 5/6, epidermal growth factor receptor, and p53 and fluorescence in situ hybridization of human epidermal growth factor receptor 2 in individual foci of 65 cases of multifocal/multicentric invasive ductal carcinoma and the associated ductal carcinoma in situ components using tissue microarrays. "
01/01/2013 - "The expression of estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), epidermal growth factor receptor (EGFR), and cytokeratin 5/6 (CK5/6), Ki67 and p53 were analyzed by immunohistochemistry and compared with patient outcome, and its implications and chemotherapy response were evaluated in four subgroups: typical medullary carcinoma (TMC), atypical medullary carcinoma (AMC), non-specific invasive ductal carcinoma (IDC) and other types. "
01/01/2015 - "We assessed the clinicopathological characteristics of 73 cases of CNC and 30 control cases of high-grade infiltrating ductal carcinoma (IDC) with focal necrosis based on light microscopy and immunohistochemical staining for estrogen receptor, progesterone receptor, Cerb-B2/HER2, Ki-67, epidermal growth factor receptor, cytokeratin 5/6, smooth muscle actin, S-100 protein, p63 and CD10. "
9. gadobenic acid (gadobenate dimeglumine)FDA Link
10. Gadolinium DTPA (Magnevist)FDA Link

Therapies and Procedures

1. Adjuvant Chemotherapy
2. Segmental Mastectomy (Lumpectomy)
3. Drug Therapy (Chemotherapy)
4. Radiotherapy
5. Simple Mastectomy