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Proteinase-Activated Receptors

A class of receptors that are activated by the action of PROTEINASES. The most notable examples are the THROMBIN RECEPTORS. The receptors contain cryptic ligands that are exposed upon the selective proteolysis of specific N-terminal cleavage sites.
Also Known As:
Receptors, Proteinase-Activated; Endopeptidase-Activated Receptors; Protease-Activated Receptors; Endopeptidase Activated Receptor; Endopeptidase Activated Receptors; Protease Activated Receptor; Protease Activated Receptors; Proteinase Activated Receptor; Proteinase Activated Receptors; Receptor, Endopeptidase-Activated; Receptor, Protease-Activated; Receptor, Proteinase-Activated; Receptors, Endopeptidase-Activated; Receptors, Protease-Activated; Receptors, Proteinase Activated; Endopeptidase-Activated Receptor; Protease-Activated Receptor; Proteinase-Activated Receptor
Networked: 644 relevant articles (5 outcomes, 52 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Hollenberg, Morley D: 30 articles (05/2021 - 08/2002)
2. Ruf, Wolfram: 21 articles (01/2022 - 04/2003)
3. Vergnolle, Nathalie: 16 articles (05/2021 - 10/2003)
4. Spek, C Arnold: 13 articles (12/2020 - 01/2008)
5. Mackman, Nigel: 9 articles (01/2019 - 02/2004)
6. Panzer, Simon: 8 articles (08/2022 - 05/2013)
7. Pawlinski, Rafal: 8 articles (05/2016 - 02/2004)
8. McDougall, Jason J: 7 articles (08/2021 - 01/2006)
9. Oikonomopoulou, Katerina: 7 articles (01/2018 - 06/2008)
10. Kaufmann, Roland: 7 articles (05/2015 - 06/2007)

Related Diseases

1. Thrombosis (Thrombus)
2. Colorectal Neoplasms (Colorectal Cancer)
3. Tendon Injuries
4. Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
5. Cerebrovascular Disorders (Cerebrovascular Occlusion)

Related Drugs and Biologics

1. Thrombin
2. Aspirin (Acetylsalicylic Acid)
3. Adenosine Diphosphate (ADP)
4. Purinergic P2Y Receptor Antagonists
5. Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)
6. Thromboxane A2 (A2, Thromboxane)
7. Trefoil Factors
8. Thrombin Receptors (Thrombin Receptor)
9. Tryptases (Tryptase)
10. Peptide Hydrolases (Proteases)

Related Therapies and Procedures

1. Therapeutics
2. Electroacupuncture
3. Transjugular Intrahepatic Portasystemic Shunt
4. Stents
5. Ligation