Type 3 Galanin Receptor

A galanin receptor subtype with high affinity for GALANIN-LIKE PEPTIDE and low affinity for full length GALANIN and galanin peptide fragments.

Also Known As:

Receptor, Galanin, Type 3; GALR3 Galanin Receptor; Galanin-3 Receptor; Galanin 3 Receptor; Galanin Receptor, GALR3; Receptor, Galanin-3; Galanin Receptor 3

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - G-Protein-Coupled Receptors: 4701
        Galanin Receptors: 151
        Type 3 Galanin Receptor: 7
        human GALR3 protein
        mouse GALR3 protein

Experts

1.	Kofler, Barbara: 5 articles (12/2021 - 02/2009)
2.	Brunner, Susanne M: 4 articles (12/2021 - 01/2016)
3.	Lang, Roland: 2 articles (12/2021 - 01/2018)
4.	Botz, Bálint: 2 articles (01/2016 - 01/2016)
5.	Helyes, Zsuzsanna: 2 articles (01/2016 - 01/2016)
6.	Kemény, Ágnes: 2 articles (01/2016 - 01/2016)
7.	McDougall, Jason J: 2 articles (01/2016 - 01/2016)
8.	Pintér, Erika: 2 articles (01/2016 - 01/2016)
9.	Bereswill, Stefan: 1 article (12/2021)
10.	Emberger, Michael: 1 article (12/2021)

Related Diseases

1.	Inflammation (Inflammations) 12/01/2021 - "Galanin receptor 3 attenuates inflammation and influences the gut microbiota in an experimental murine colitis model." 01/01/2018 - "Our data indicate that galanin receptor 3, but not galanin receptor 2, plays an important role in psoriasis-like skin inflammation."
2.	Psoriasis (Pustulosis Palmaris et Plantaris) 01/01/2018 - "Lack of Galanin Receptor 3 Alleviates Psoriasis by Altering Vascularization, Immune Cell Infiltration, and Cytokine Expression." 01/01/2018 - "Our data indicate that galanin receptor 3, but not galanin receptor 2, plays an important role in psoriasis-like skin inflammation." 01/01/2018 - "Moreover, in a murine psoriasis model, we showed that C57/BL6 mice lacking galanin receptor 3 display a milder course of psoriasis upon imiquimod treatment, leading to decreased disease severity, delayed neo-vascularization, reduced infiltration of neutrophils, and significantly lower levels of proinflammatory cytokines compared with wild-type mice. "
3.	Pain (Aches) 06/01/2017 - "Galanin Receptor 3 (GALR3) is a G-protein-coupled receptor with a widespread distribution in the brain and plays a role in a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. "
4.	Edema (Dropsy) 02/01/2009 - "Evidence that the modulatory effect of galanin on inflammatory edema formation is mediated by the galanin receptor 3 in the murine microvasculature."
5.	Contact Dermatitis (Eczema, Contact) 01/01/2016 - "Galanin 3 receptor-deficient mice show no alteration in the oxazolone-induced contact dermatitis phenotype."

Related Drugs and Biologics

1.	Type 2 Galanin Receptor
2.	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)
3.	Galanin
4.	Cytokines
5.	Oxazolone
6.	Hormones (Hormone)
7.	Imiquimod (Aldara)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)