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11-beta-Hydroxysteroid Dehydrogenase Type 1

A low-affinity 11 beta-hydroxysteroid dehydrogenase found in a variety of tissues, most notably in LIVER; LUNG; ADIPOSE TISSUE; vascular tissue; OVARY; and the CENTRAL NERVOUS SYSTEM. The enzyme acts reversibly and can use either NAD or NADP as cofactors.
Also Known As:
11 beta-Hydroxysteroid Dehydrogenase Type 1; 11beta-HSD1; 11beta-HSD1 Reductase; 11beta-Hydroxysteroid Dehydrogenase Type 1; 11beta HSD1 Reductase; 11beta Hydroxysteroid Dehydrogenase Type 1
Networked: 290 relevant articles (20 outcomes, 32 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Stewart, Paul M: 31 articles (03/2011 - 01/2002)
2. Walker, Brian R: 30 articles (01/2014 - 07/2002)
3. Seckl, Jonathan R: 27 articles (01/2014 - 11/2002)
4. Tomlinson, Jeremy W: 17 articles (12/2010 - 01/2002)
5. Andrew, Ruth: 12 articles (01/2013 - 07/2002)
6. Stewart, P M: 12 articles (06/2010 - 01/2001)
7. Walker, Elizabeth A: 11 articles (03/2011 - 01/2002)
8. Odermatt, Alex: 11 articles (03/2010 - 12/2003)
9. Morton, Nicholas M: 10 articles (01/2014 - 07/2003)
10. Chapman, Karen E: 10 articles (01/2013 - 01/2004)

Related Diseases

1. Metabolic Syndrome (Dysmetabolic Syndrome X)
2. Insulin Resistance
3. Obesity
4. Type 2 Diabetes Mellitus (MODY)
5. Body Weight (Weight, Body)

Related Drugs and Biologics

1. Glucocorticoids
2. Hydrocortisone (Cortisol)
3. 11-beta-Hydroxysteroid Dehydrogenase Type 1
4. Enzymes
5. Glucose (Dextrose)
6. Lipids
7. Cortisone
8. PPAR gamma
9. Leptin
10. Triglycerides (Triacylglycerol)

Related Therapies and Procedures

1. Therapeutics
2. Glycemic Control
3. Carbohydrate-Restricted Diet (Low Carbohydrate Diet)
4. Highly Active Antiretroviral Therapy (HAART)
5. Islets of Langerhans Transplantation