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TIE-2 Receptor (Receptor, TIE 2)

A TIE receptor tyrosine kinase that is found almost exclusively on ENDOTHELIAL CELLS. It is required for both normal embryonic vascular development (NEOVASCULARIZATION, PHYSIOLOGIC) and tumor angiogenesis (NEOVASCULARIZATION, PATHOLOGIC).
Also Known As:
Receptor, TIE 2; Receptor, TIE-2; Angiopoietin Receptor Tie-2; TIE-2-RTK; TIE2 Tyrosine Kinase; Tek Receptor; Tie2 Receptor; Angiopoietin Receptor Tie 2; Receptor Tie-2, Angiopoietin; Receptor, Tek; Receptor, Tie2; TIE 2 Receptor Tyrosine Kinase; Tie-2, Angiopoietin Receptor; Tyrosine Kinase, TIE2; TIE-2 Receptor Tyrosine Kinase
Networked: 232 relevant articles (4 outcomes, 27 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Kümpers, Philipp: 6 articles (11/2019 - 01/2008)
2. David, Sascha: 6 articles (03/2016 - 01/2008)
3. Koh, Gou Young: 5 articles (01/2020 - 02/2005)
4. Lip, G Y H: 5 articles (10/2005 - 07/2003)
5. Alitalo, Kari: 4 articles (01/2020 - 09/2002)
6. Lukasz, Alexander: 4 articles (11/2019 - 01/2008)
7. Baumeister, Sebastian E: 4 articles (10/2016 - 12/2013)
8. Lieb, Wolfgang: 4 articles (10/2016 - 12/2013)
9. Lorbeer, Roberto: 4 articles (10/2016 - 12/2013)
10. Nauck, Matthias: 4 articles (10/2016 - 12/2013)

Related Diseases

1. Neoplasms (Cancer)
2. Hemangiosarcoma (Angiosarcoma)
3. Hypoxia (Hypoxemia)
4. Colorectal Neoplasms (Colorectal Cancer)
5. Breast Neoplasms (Breast Cancer)

Related Drugs and Biologics

1. trebananib
2. Angiopoietin-1
3. Peptides (Polypeptides)
4. Proteins (Proteins, Gene)
5. Cisplatin (Platino)
6. Capecitabine (Xeloda)
7. Angiopoietin-2
8. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
9. Angiopoietins
10. Protein-Tyrosine Kinases (Tyrosine Kinase)

Related Therapies and Procedures

1. Hematopoietic Stem Cell Transplantation
2. Therapeutics
3. Drug Therapy (Chemotherapy)
4. Light Coagulation
5. Lasers (Laser)