A TIE receptor tyrosine kinase that is found almost exclusively on ENDOTHELIAL CELLS. It is required for both normal embryonic vascular development (NEOVASCULARIZATION, PHYSIOLOGIC) and tumor angiogenesis (NEOVASCULARIZATION, PATHOLOGIC).
Also Known As:
Receptor, TIE 2; Receptor, TIE-2; Angiopoietin Receptor Tie-2; TIE-2-RTK; TIE2 Tyrosine Kinase; Tek Receptor; Tie2 Receptor; Angiopoietin Receptor Tie 2; Receptor Tie-2, Angiopoietin; Receptor, Tek; Receptor, Tie2; TIE 2 Receptor Tyrosine Kinase; Tie-2, Angiopoietin Receptor; Tyrosine Kinase, TIE2; TIE-2 Receptor Tyrosine Kinase