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Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)

A 200-230-kDa tyrosine kinase receptor for vascular endothelial growth factors found primarily in endothelial and hematopoietic cells and their precursors. VEGFR-2 is important for vascular and hematopoietic development, and mediates almost all endothelial cell responses to VEGF.
Also Known As:
Vascular Endothelial Growth Factor Receptor 2; Fetal Liver Kinase-1; Flk-1 Protein; Flk-1 Receptor Tyrosine Kinase; KDR Tyrosine Kinase; Kinase Insert Domain Receptor; VEGF Receptor Flk-1; VEGF Receptor KDR; Fetal Liver Kinase 1; Flk 1 Protein; Flk 1 Receptor Tyrosine Kinase; Flk-1, VEGF Receptor; KDR, VEGF Receptor; Tyrosine Kinase, KDR; VEGF Receptor Flk 1; VEGFR-2
Networked: 2196 relevant articles (90 outcomes, 312 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Hicklin, Daniel J: 26 articles (06/2009 - 04/2002)
2. Zhu, Zhenping: 11 articles (09/2009 - 09/2004)
3. Wang, Min: 10 articles (02/2021 - 11/2009)
4. Ali, Mamdouh M: 10 articles (02/2020 - 07/2015)
5. Hicklin, D J: 10 articles (05/2006 - 05/2000)
6. Bohlen, Peter: 10 articles (11/2005 - 06/2002)
7. Eissa, Ibrahim H: 9 articles (12/2022 - 01/2020)
8. Zhang, Juan: 9 articles (02/2021 - 11/2009)
9. Zhang, Jie: 9 articles (02/2019 - 01/2010)
10. Alitalo, Kari: 9 articles (06/2015 - 10/2003)

Related Diseases

1. Neoplasms (Cancer)
2. Stomach Neoplasms (Stomach Cancer)
3. Neoplasm Metastasis (Metastasis)
4. Melanoma (Melanoma, Malignant)
5. Breast Neoplasms (Breast Cancer)

Related Drugs and Biologics

1. apatinib
2. Tyrosine Kinase Inhibitors
3. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
4. Ramucirumab
5. Monoclonal Antibodies
6. Phosphotransferases (Kinase)
7. ErbB Receptors (EGF Receptor)
8. cabozantinib
9. Vascular Endothelial Growth Factor Receptor-3 (Flt 4)
10. Sorafenib (BAY 43-9006)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Castration
4. Immunotherapy
5. Brachytherapy