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Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)

A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction.
Also Known As:
fms-Like Tyrosine Kinase; Vascular Endothelial Growth Factor Receptor 1; FLT1 RTK; FLT1 Receptor Tyrosine Kinase; Proto-Oncogene Protein flt; VEGF Receptor flt-1 Protein; VEGF Receptor, FLT; FLT VEGF Receptor; Proto Oncogene Protein flt; Receptor, FLT VEGF; Tyrosine Kinase, fms-Like; VEGF Receptor flt 1 Protein; VEGFR-1
Networked: 1319 relevant articles (33 outcomes, 184 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Karumanchi, S Ananth: 57 articles (03/2022 - 03/2003)
2. Rana, Sarosh: 25 articles (03/2022 - 02/2007)
3. Shibuya, Masabumi: 23 articles (10/2021 - 10/2002)
4. Romero, Roberto: 18 articles (01/2022 - 06/2004)
5. Stepan, Holger: 16 articles (03/2022 - 04/2007)
6. Thadhani, Ravi: 14 articles (12/2017 - 02/2004)
7. Chaiworapongsa, Tinnakorn: 13 articles (01/2022 - 06/2004)
8. Salahuddin, Saira: 13 articles (10/2020 - 07/2007)
9. Rajakumar, Augustine: 13 articles (01/2019 - 12/2004)
10. Ohkuchi, Akihide: 12 articles (01/2021 - 09/2005)

Related Diseases

1. Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
2. Pre-Eclampsia (Preeclampsia)
3. Neoplasms (Cancer)
4. Breast Neoplasms (Breast Cancer)
5. Inflammation (Inflammations)

Related Drugs and Biologics

1. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
2. Intercellular Signaling Peptides and Proteins (Growth Factors)
3. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
4. Ligands
5. Cytokines
6. Interleukin-6 (Interleukin 6)
7. Thymidine Kinase
8. Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)
9. Endoglin
10. Vascular Endothelial Growth Factor Receptors (VEGF Receptors)

Related Therapies and Procedures

1. Therapeutics
2. Cell Transplantation
3. Drug Therapy (Chemotherapy)
4. Hematopoietic Stem Cell Transplantation
5. Sutures (Suture)