This integrin alpha subunit combines with INTEGRIN BETA1 to form a receptor (INTEGRIN ALPHA5BETA1) that binds FIBRONECTIN and LAMININ. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds.
Also Known As:
CD49e Antigen; Integrin alphaF; Platelet Glycoprotein Ic; VLA-5 alpha Chain; alpha(5) Integrin; alpha5 Integrin; Antigen, CD49e; Glycoprotein Ic, Platelet; Ic, Platelet Glycoprotein; Integrin, alpha5; VLA 5 alpha Chain; alpha Chain, VLA-5; alpha5, Integrin; alphaF, Integrin; Antigens, CD49e; CD49e Antigens