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Integrin alpha4

An integrin alpha subunit that is unique in that it does not contain an I-domain, and its proteolytic cleavage site is near the middle of the extracellular portion of the polypeptide rather than close to the membrane, as in other integrin alpha subunits.
Also Known As:
CD49d Antigen; alpha4 Integrin; Integrin, alpha4; Antigens, CD49d; CD49d Antigens
Networked: 81 relevant articles (9 outcomes, 15 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Ginsberg, Mark H: 4 articles (02/2009 - 11/2002)
2. Bönig, Halvard: 2 articles (01/2014 - 03/2013)
3. Kim, Yong-Mi: 2 articles (01/2014 - 03/2013)
4. Kim, Hyeon Soo: 2 articles (02/2010 - 06/2009)
5. Lee, Eun Soo: 2 articles (02/2010 - 06/2009)
6. Lee, Yun Mi: 2 articles (02/2010 - 06/2009)
7. Park, Sun-Hwa: 2 articles (02/2010 - 06/2009)
8. Uhm, Kyung-Ok: 2 articles (02/2010 - 06/2009)
9. Kim, Duk-Hwan: 2 articles (11/2008 - 09/2008)
10. Park, Joobae: 2 articles (11/2008 - 09/2008)

Related Diseases

1. Crohn Disease (Crohn's Disease)
2. Multiple Sclerosis
3. Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
4. Progressive Multifocal Leukoencephalopathy
5. Disease Progression

Related Drugs and Biologics

1. Natalizumab (Tysabri)
2. Monoclonal Antibodies
3. Integrin alpha4beta1 (VLA-4)
4. Cell Adhesion Molecules
5. Antibodies
6. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
7. Immunoglobulin G (IgG)
8. Immunoglobulin Fab Fragments
9. Infliximab (Remicade)
10. Adalimumab (Humira)

Related Therapies and Procedures

1. Therapeutics
2. Intravenous Injections
3. Drug Therapy (Chemotherapy)