Galactolipids

A group of GLYCOLIPIDS in which the sugar group is GALACTOSE. They are distinguished from GLYCOSPHINGOLIPIDS in lacking nitrogen. They constitute the majority of MEMBRANE LIPIDS in PLANTS.

Also Known As:

Networked: 66 relevant articles (1 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Ohta, Hiroyuki: 7 articles (09/2019 - 03/2005)
2.	Nakamura, Yuki: 4 articles (09/2017 - 03/2005)
3.	Shimojima, Mie: 3 articles (09/2019 - 12/2009)
4.	Shyur, Lie-Fen: 3 articles (12/2018 - 07/2007)
5.	Kobayashi, Koichi: 3 articles (01/2013 - 07/2006)
6.	Masuda, Tatsuru: 3 articles (01/2013 - 03/2005)
7.	Wang, Yanting: 2 articles (07/2021 - 01/2020)
8.	Murakawa, Masato: 2 articles (09/2019 - 01/2015)
9.	Yang, Chung-Chih: 2 articles (12/2018 - 05/2016)
10.	Chen, Guo-Rong: 2 articles (05/2015 - 03/2012)

Related Diseases

1.	Sepsis (Septicemia) 05/01/2016 - "In this study, we conducted a comparative oxylipin metabolomics study to gain a comprehensive picture of lipid mediator dynamics during the initial hyperinflammatory phase of sepsis, and demonstrated, in parallel, the efficacy of simvastatin and plant galactolipid, 1,2-di-O-α-linolenoyl-3-O-β-galactopyranosyl-sn-glycerol (dLGG) in the homeostatic regulation of the oxylipin metabolome using a lipopolysaccharide (LPS)-induced sepsis C57BL/6J mouse model. "
2.	Neoplasms (Cancer) 07/15/2007 - "This study shows the detailed molecular mechanism(s) underlying the anti-inflammatory and tumor-suppressive effects of a natural galactolipid." 03/01/2012 - "The anomeric mixture of a series of O-galactolipid derivatives is revealed to be more toxic against several cancer cell lines than their either single component with the pure α- or β-configuration. " 03/01/2012 - "The anomeric mixture of some O-galactolipid derivatives is more toxic against cancer cells than either anomer alone." 01/01/2009 - "Furthermore, compound 1 has been isolated from spinach and several medicinal plants by bioassay-guided fractionation as a galactolipid with possible cancer preventive effects. " 01/01/2009 - "Several galactolipids have been shown to possess in vitro and/or in vivo anti-tumor promoting activity and anti-inflammatory activity. "
3.	Pick Disease of the Brain (Pick's Disease) 11/01/1987 - "Marked loss of cerebral galactolipids in Pick's disease." 11/01/1987 - "Studies with two monoclonal antibodies reactive with galactolipids suggest that there is a marked loss of these compounds in the brains of patients with Pick's disease. " 07/01/1988 - "Additionally, the galactolipid composition of Pick's disease has also been studied using these antibodies."
4.	Melanoma (Melanoma, Malignant) 12/15/2018 - "This study demonstrates the bioefficacy and gives mechanistic insights into a plant galactolipid 1,2-di-O-linolenoyl-3-O-β-galactopyranosyl-sn-glycerol (dLGG) against metastatic melanoma using a syngeneic mouse model implanted with B16COX-2/Luc melanoma. " 10/01/2021 - "Multidirectional anti-melanoma effect of galactolipids (MGDG-1 and DGDG-1) from Impatiens parviflora DC. " 10/01/2021 - "The anti-melanoma potential of galactolipids: MGDG-1 and DGDG-1, isolated from Impatiens parviflora, and their synergistic effect with anticancer drug - doxorubicin (DOX) was investigated. " 12/15/2018 - "Plant galactolipid dLGG suppresses lung metastasis of melanoma through deregulating TNF-α-mediated pulmonary vascular permeability and circulating oxylipin dynamics in mice."
5.	Multiple Myeloma 05/18/2015 - "This study describes an interesting observation that the mixture of anomeric galactolipids has synergistic effects on the growth inhibition of human multiple myeloma (MM) cells. " 05/18/2015 - "Mixed galactolipid anomers accentuate apoptosis of multiple myeloma cells by inducing DNA damage."

Related Drugs and Biologics

1.	Lipids
2.	Oxylipins
3.	Simvastatin (Zocor)
4.	Lipopolysaccharides
5.	Monoclonal Antibodies
6.	Phospholipids (Phosphatides)
7.	Phosphates (Orthophosphate)
8.	Enzymes
9.	Proteins (Proteins, Gene)
10.	Membrane Lipids