beta-Crystallins
A class of crystallins that provides refractive power and translucency to the lens (LENS, CRYSTALLINE) in VERTEBRATES. Beta-crystallins are similar in structure to GAMMA-CRYSTALLINS in that they both contain Greek key motifs. Beta-crystallins exist as oligomers formed from acidic (BETA-CRYSTALLIN A CHAIN) and basic (BETA-CRYSTALLIN B CHAIN) subunits.
Also Known As:
beta-Crystallin; beta Crystallin; beta Crystallins; Crystallins, beta
Networked: 67
relevant articles (1 outcomes,
3 trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Experts
1. | Lampi, Kirsten J:
3 articles
(06/2010 - 11/2002)
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2. | Graw, Jochen:
2 articles
(12/2009 - 03/2003)
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3. | Chauke, Chesa G:
1 article
(01/2020)
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4. | Khoza, Sanele:
1 article
(01/2020)
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5. | Magwebu, Zandisiwe E:
1 article
(01/2020)
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6. | Ngqaneka, Thobile:
1 article
(01/2020)
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7. | Dulle, Jennifer E:
1 article
(01/2017)
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8. | Fort, Patrice E:
1 article
(01/2017)
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9. | Garnai, Sarah J:
1 article
(01/2017)
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10. | Pawar, Hemant S:
1 article
(01/2017)
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Related Diseases
1. | Cataract (Cataracts)
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2. | Ganglion Cysts (Ganglion)
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3. | Inflammation (Inflammations)
11/01/2005
- " Treatment of bile duct-ligated rats with this conjugate reduced hepatic inflammation and hepatic alpha-beta-Crystallin mRNA expression, a marker for HSC activation. " 01/01/2014
- " Many autoantibodies (antibodies against alpha beta crystallin, alpha-actinin, amyloid, C1q, chondroitin, collagen I, collagen III, collagen IV, elastin, fibronectin, heparan sulfate, histone H2A, histone H2B, hyaluronic acid, laminin, proteoglycan, vimentin, vitronectin, and aldolase C and pyruvate kinase M2) and overexpression of Fcc receptors play role in immune-mediated inflammation in AMD patients and in animal model. "
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4. | Frontotemporal Dementia (Semantic Dementia)
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5. | Pick Disease of the Brain (Pick's Disease)
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Related Drugs and Biologics
Related Therapies and Procedures