The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.
Also Known As:
Luteinizing Hormone, beta Subunit; LH-beta; Luteinizing Hormone, beta Chain; Luteinizing Hormone, beta Polypeptide Chain; Lutropin-beta; LH beta; Lutropin beta; ICSH, beta Subunit; LH, beta Subunit; Lutropin, beta Subunit