Ginsenosides

01/01/2016 - "Accumulating reports have shown that ginsenosides, the major active component of ginseng, were helpful for tumor treatment. "
03/24/2023 - "This review introduces current studies on the therapeutic efficacy of ginsenosides in alleviating NF-κB responses and emphasizes the critical role of ginsenosides in severe inflammatory diseases as well as cancers."
01/01/2021 - "Furthermore, an in vivo investigation of these ginsenosides should be conducted to gain insight into the dysregulation of several pathways, followed by clinical trials for the potential and effective treatment of cancer."
01/01/2023 - "In this review, we provide a detailed and up-to-date summary of research evidence for antilung cancer and anti-inflammatory protective effects of ginsenosides and their potential molecular mechanisms."
01/01/2019 - "These findings demonstrate that ginsenosides F1 and Rh1 can be a promising herbal remedy for vessel normalization in ischemic disease and cancer and that NR4A1 is the key target."

10/01/1994 - "We conclude that both Ginsenoside in total and Ginsenoside Rb have protective effects on myocardiac ischemic and reperfusion injuries in open heart surgery, and the effect of Ginsenoside in total is even better than that of Ginsenoside Rb."
10/01/1994 - "Thirty mitral valvular surgical patients were randomly divided into three groups for study of protective effects of Ginsenoside on myocardiac ischemic and reperfusion injuries. "
10/01/1994 - "[Protective effects of ginsenoside on myocardiac ischemic and reperfusion injuries]."
01/01/2020 - "Ginsenosides play a protective role in ischemia-reperfusion injury. "
10/29/2012 - "To elucidate the underlying mechanism of cardio-protective activity of the total ginsenosides (TGS) of Radix Ginseng, proteomic analysis using two-dimensional gel electrophoresis (2-DE) and MALDI-TOF-TOF-MS techniques was employed for identifying the underlying targets of TGS on improvement of the energy metabolism of isolated rat heart tissues perfused in Langendorff system under ischemia-reperfusion injury conditions. "

09/01/2022 - "The ginsenoside-loaded MMIPs were then shown to have protective effects on mitochondrial membrane potential and cellular viability for H9c2 cells treated with CoCl2 to mimic hypoxia injury. "
03/01/2021 - "This project aimed to explore the protective effect of ginsenoside Rg_1 on hypoxia/reoxygenation(H/R)-induced H9 c2 cardiomyocyte injury and its underlying signaling pathway. "
03/01/2021 - "[Protective effect of ginsenoside Rg_1 on hypoxia/reoxygenation injury and its mechanism]."
01/01/2018 - "We aimed to explore the functional roles of ginsenoside (Gin) Rg1 in cardiomyocytes under hypoxia and to clarify underlying mechanisms. "
12/16/2017 - "Furthermore, the immunoblotting analysis demonstrated that ginsenosides activate AMPK but suppress JNK signaling pathways during hypoxia/reoxygenation. "

01/01/2023 - "Ginsenosides have been reported to protect diabetics from tissue damage, inflammation, and insulin resistance. "
09/15/2020 - "Ginsenoside Mc1 improves liver steatosis and insulin resistance by attenuating ER stress."
01/01/2022 - "Ameliorative Effects of Malonyl Ginsenoside from Panax ginseng on Glucose-Lipid Metabolism and Insulin Resistance via IRS1/PI3K/Akt and AMPK Signaling Pathways in Type 2 Diabetic Mice."
08/01/2019 - "Corrigendum to ``Rare ginsenosides ameliorate lipid overload-induced myocardial insulin resistance via modulating metabolic flexibility'' [Phytomedicine 58 (2019) 152745]."
05/01/2019 - "Rare ginsenosides ameliorate lipid overload-induced myocardial insulin resistance via modulating metabolic flexibility."

11/01/1990 - "Electrocardiographic findings of myocardial ischemia were significantly improved in the ginsenosides group. "
01/01/2020 - "This paper reviews the protective effects of ginsenosides on myocardial ischemia and ischemiareperfusion injury."
03/01/2019 - "Mechanisms underlying the cardio-protection of total ginsenosides against myocardial ischemia in rats in vivo and in vitro: Possible involvement of L-type Ca2+ channels, contractility and Ca2+ homeostasis."
11/01/2010 - "Ginseng is the most popular herb used for treatment of ischemic heart diseases in Chinese community; ginsenosides are considered to be the major active ingredients. "
01/01/2020 - "The Advances on the Protective Effects of Ginsenosides on Myocardial Ischemia and Ischemia-Reperfusion Injury."