Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation)

Transplantation of PERIPHERAL BLOOD STEM CELLS. It is a less invasive alternative to direct marrow harvesting of hematopoietic stem cells. Enrichment of stem cells in peripheral blood can be achieved by inducing mobilization of stem cells from the BONE MARROW.

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Networked: 1966 relevant articles (205 outcomes, 194 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Harada, Mine: 21 articles (01/2021 - 04/2002)
2.	Yu, Li: 16 articles (02/2021 - 02/2006)
3.	Atsuta, Yoshiko: 14 articles (10/2022 - 02/2006)
4.	Teshima, Takanori: 14 articles (01/2022 - 04/2007)
5.	Nagafuji, Koji: 13 articles (01/2022 - 11/2003)
6.	Harada, M: 13 articles (04/2006 - 10/2000)
7.	Fukuda, Takahiro: 12 articles (10/2022 - 09/2012)
8.	Dispenzieri, Angela: 11 articles (01/2015 - 01/2002)
9.	Ho, A D: 11 articles (04/2008 - 05/2000)
10.	Gao, Chunji: 10 articles (02/2022 - 06/2012)

Related Diseases

1.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/01/2023 - "This study aimed to validate the utility of the transplant conditioning intensity (TCI) score in 1714 patients with acute myeloid leukemia (AML) undergoing allogeneic bone marrow or peripheral blood stem cell transplantation (BMT/PBSCT) and assess its applicability to 753 patients with AML undergoing umbilical cord blood transplantation (UCBT) both during first complete remission. " 07/01/2010 - "Tandem versus single autologous peripheral blood stem cell transplantation as post-remission therapy in adult acute myeloid leukemia patients under 60 in first complete remission: results of the multicenter prospective phase III GOELAMS LAM-2001 trial." 05/01/2019 - "To compare the safety and efficacy of prophylactic DLI for prevention of relapse after allogeneic peripheral blood stem cell transplantation from haploidentical donors (HID-SCT) and matched-sibling donors (MSD-SCT) in patients with very high-risk acute myeloid leukemia (AML), we performed a retrospective analysis in a cohort of 21 HID-SCT and 13 MSD-SCT recipients, displaying similar baseline characteristics except for donor's gender distribution. " 08/01/2013 - "We retrospectively analyzed the outcomes of 81 patients with non-M3 acute myelogenous leukemia (AML) in first complete remission (CR1) who were treated with high-dose chemotherapy (HDCT) and autologous peripheral blood stem cell transplantation (Auto-PBSCT) by the Fukuoka Blood and Marrow Transplantation Group between 1989 and 2005. " 12/01/2005 - "FLT3 mutations in normal karyotype acute myeloid leukemia in first complete remission treated with autologous peripheral blood stem cell transplantation."
2.	Non-Hodgkin Lymphoma (Lymphosarcoma) 12/01/2006 - "A 43-year-old female with large T-cell non-Hodgkin's lymphoma and central nervous system (CNS) involvement underwent HLA-identical-sibling peripheral blood stem cell transplantation (SCT) during her third complete remission. " 05/01/1998 - "Three patients with non-Hodgkin's lymphoma of intermediate-grade histologies, who had failed to achieve a complete remission (CR) after more than several courses of conventional chemotherapy were treated with two cycles of high-dose chemotherapy with autologous peripheral blood stem cell transplantation (double PBSCT). " 10/01/1999 - "We conducted a multicenter early phase II study to evaluate the feasibility and therapeutic efficacy of high-dose chemotherapy supported by autologous peripheral blood stem cell transplantation (auto-PBSCT) for the treatment of intermediate grade non-Hodgkin's lymphoma (IG-NHL). " 08/01/2001 - "Although high-dose chemotherapy with autologous peripheral blood stem cell transplantation (autoPBSCT) has been shown or confirmed to be an effective treatment for high-risk and relapsed non-Hodgkin's lymphoma (NHL), relapse after autoPBSCT remains a serious problem. " 03/01/2001 - "[High-dose therapy and peripheral blood stem cell transplantation for patients with aggressive non-Hodgkin's lymphoma remaining in initial remission: results of a feasibility study]."
3.	Neoplasms (Cancer) 11/01/2020 - "He obtained a complete remission after cancer chemotherapy and received peripheral blood stem cell transplantation from a histocompatible sibling. " 09/01/2013 - "Sustained complete remission in an elderly patient with a blastic plasmacytoid dendritic cell neoplasm following autologous peripheral blood stem cell transplantation." 04/01/2010 - "To investigate the efficacy of high dose chemotherapy combined with autologous peripheral blood stem cell transplantation (APBSCT) for the treatment of neural ectodermal solid tumor originated from neural crest in children. " 10/01/2003 - "Only one patient who received en bloc resection of the tumor combined with multiagent chemotherapy followed by high-dose chemotherapy with peripheral blood stem cell transplantation remains alive and continues to be disease free. " 01/01/2019 - "Peripheral blood stem cell transplantation (PBSCT) has increasingly been used for hematologic cancer therapy, resulting in improved survival rates. "
4.	Multiple Myeloma 10/01/1999 - "We add to this evidence by reporting complete remission achieved by withdrawal of immunosuppression in a patient with multiple myeloma progressing after HLA-identical sibling peripheral stem cell transplantation. " 09/01/2018 - "High-dose chemotherapy followed by autologous peripheral blood stem cell transplantation (auto-PBSCT) remains the mainstay of treatment of eligible patients diagnosed multiple myeloma. " 03/01/2006 - "Efficacy of diverse high-dose regimens followed by autologous peripheral blood stem cell transplantation in consecutive multiple myeloma patients: a single-centre analysis over a 12-year period." 03/01/2004 - "Both single and tandem cycles of high dose therapy and autologous peripheral blood stem cell transplantation (ASCT) have been shown to improve survival in multiple myeloma (MM) patients. " 10/01/2003 - "High dose therapy followed by autologous peripheral blood stem cell transplantation as a first line treatment for multiple myeloma: a Korean Multicenter Study."
5.	Graft vs Host Disease (Graft-Versus-Host Disease) 01/01/2023 - "Peripheral blood stem cell transplantation increases the occurrence of graft-versus-host disease but may have more improved transplant outcomes compared with bone marrow transplantation. " 07/01/2000 - "Either the depletion of regulatory cells from the graft by enrichment of CD34(+) cells or the abolition of the autoregulation by including total body irradiation in the conditioning regimen may be effective in inducing autologous graft-versus-host disease after peripheral blood stem cell transplantation. " 10/01/2009 - "Although he received allogeneic peripheral blood stem cell transplantation after the first remission, he died 9 months after the initial diagnosis due to relapse of the disease and graft-versus-host disease. " 01/01/2018 - "Recent studies have revealed that HLA-identical sibling peripheral blood stem cell transplantation (PBSCT) had been providing impaired graft-versus-host disease (GVHD)-free relapse-free survival (GRFS) due to a higher risk of GVHD. " 06/01/2014 - "While previous studies have shown comparable clinical results for related and unrelated bone marrow transplantation (BMT), the transplantation outcomes for related and unrelated peripheral blood stem cell transplantation (PBSCT) may not follow the same pattern due to a higher incidence of graft-versus-host disease (GVHD)-related morbidity and mortality in the case of long-term survival after unrelated PBSCT. "

Related Drugs and Biologics

1.	Cyclophosphamide (Cytoxan)
2.	Melphalan (Alkeran)
3.	Rituximab (Mabthera)
4.	Cytarabine (Cytosar-U)
5.	Cyclosporine (Ciclosporin)
6.	fludarabine
7.	Busulfan (Busulfex)
8.	Antilymphocyte Serum (Anti-Thymocyte Globulin)
9.	Dexamethasone (Maxidex)
10.	Etoposide (VP 16)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Therapeutics
3.	Transplantation
4.	Bone Marrow Transplantation (Transplantation, Bone Marrow)
5.	Radiotherapy