HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Investigational Therapies (Experimental Therapy)

Subscribe to New Research on Investigational Therapies

Treatments which are undergoing clinical trials or for which there is insufficient evidence to determine their effects on health outcomes; coverage for such treatments is often denied by health insurers.

Also Known As:

Experimental Therapy; Innovative Therapies; Investigational Treatment; Therapies, Investigational; Experimental Therapies; Investigational Treatments; Innovative Therapy; Investigational Therapy; Therapies, Experimental; Therapies, Innovative; Therapy, Experimental; Therapy, Innovative; Therapy, Investigational; Treatment, Investigational; Treatments, Investigational

Networked: 1387 relevant articles (68 outcomes, 170 trials/studies)

Relationship Network

Therapy Context: Research Results

Therapeutics: 15318
- Investigational Therapies: 1387
  - Compassionate Use Trials

Experts

1.	Hung, Chien-Fu: 9 articles (07/2013 - 10/2007)
2.	Zhang, Ruiwen: 9 articles (01/2013 - 02/2003)
3.	Wang, Wei: 8 articles (11/2013 - 11/2006)
4.	Wang, Hui: 8 articles (01/2011 - 02/2003)
5.	Geoerger, Birgit: 7 articles (01/2015 - 09/2009)
6.	Vassal, Gilles: 7 articles (01/2015 - 09/2009)
7.	Wu, T-C: 7 articles (07/2013 - 10/2007)
8.	Monie, Archana: 6 articles (08/2011 - 08/2008)
9.	Bossowska, A: 5 articles (05/2015 - 01/2011)
10.	Majewski, M: 5 articles (05/2015 - 01/2011)

Related Diseases

1.	Neoplasms (Cancer) 02/01/1989 - "Investigational therapy, therefore, actually represents state-of-the-art treatment that offers the patient the best chance for increased survival, tumor regression, and improved quality of life. " 01/05/2011 - "The approval of a new drug for cancer treatment by the regulatory authorities, such as the United States Food and Drug Administration or European Medicines Agency, is usually based on the positive results of one or more randomized phase III clinical trials comparing the investigational treatment with the standard treatment. " 08/01/2014 - "This experimental therapy method based on synchrotron radiation has been shown to spare normal tissue at up to 1000 Gy of peak entrance dose while still being effective in tumor eradication and extending the lifetime of tumor-bearing small animal models. " 01/01/2014 - "Experimental therapy with CAR-engineered T cells has also shown promising results on solid tumors. " 02/01/2004 - "Patient enrollment into rigorous and well conducted clinical trials, either at tumor diagnosis or after tumor recurrence, will generate new information regarding investigational therapies and it will offer improved therapies for patients with this disease."
2.	Infection 11/01/2000 - "Control of infection may be improved with new VAS designs, antibiotic impregnated drivelines, and innovative therapies such as antibiotic beads. " 01/01/2012 - "These findings indicate that combinational RNAi has tremendous promise for developing innovative therapy against viral infection." 09/01/2005 - "An in vivo animal model was developed to test the efficacy of innovative therapies for the prevention of biomaterial centered infections caused by methicillin-resistant Staphylococcus aureus bacteria (MRSA). " 10/01/1995 - "An animal model is needed to examine the development, progression, and resolution of ocular Toxoplasma infections and to study the effects on the disease of currently used and experimental therapies. " 05/01/2015 - "Investigational therapies targeting quorum-sensing for the treatment of Staphylococcus aureus infections."
3.	Sepsis (Septicemia) 01/01/2008 - "Experimental therapies are being developed with improved in vitro and animal models and better understanding of the pathophysiology of sepsis in humans. " 01/01/1995 - "Perhaps morbidity as well as mortality should be used as outcomes when testing the efficacy of innovative therapies for sepsis." 01/01/1995 - "This paper reviews the development of experimental therapies for sepsis and discusses those treatments that show promise for application in humans. " 03/01/2006 - "Because the signal with innovative therapy of sepsis is likely to be low, an oncology model clinical trial approach, in which studies start with a high-risk homogeneous population and look for a large treatment effect with smaller numbers of patients, is likely to be more relevant than the commonly used cardiology model, in which studies search for a small treatment effect using large, heterogeneous, low-risk populations. " 03/01/2006 - "Despite some recent success with clinical trials studying innovative therapies in sepsis, the field remains predominantly one of failure despite compounds with significant preclinical activity. "
4.	Glioma (Gliomas) 04/01/2000 - "Enrolment of patients into rigorous, well-conducted, clinical trials, both at tumour diagnosis and after tumour recurrence, will generate new information regarding investigational therapies and may offer improved therapies for patients with malignant gliomas." 10/01/2004 - "Neonatal rats represent a much more reliable model than adults to study experimental therapies against gliomas." 12/01/1990 - "Results are evaluated in the light of those obtained in trials of other experimental therapies for recurrent malignant gliomas. " 10/01/1990 - "A cerebral glioma model for experimental therapy and in vivo invasion studies in syngeneic BD IX rats." 09/01/1982 - "A clonogenic cell assay was developed for the chemically induced rat glioma RG2 that allows in vivo, in vitro, and in vivo to in vitro studies of cell survival after experimental therapy. "
5.	Breast Neoplasms (Breast Cancer) 01/01/1989 - "We feel that an evaluation of intensive investigational treatment approaches, such as trials using autologous bone marrow transplantation, is justified for most stage IV breast cancer patients, in view of their poor prognosis." 12/08/2013 - "Patients with primary invasive breast cancer (clinically lymph node negative and less than or equal to 3 cm in size) were randomized before surgery for completion axillary lymph node dissection (arm A-standard treatment) or axillary nodal irradiation (arm B-investigational treatment). " 10/01/2013 - "Innovative therapies for patients with metastatic breast cancer have been introduced. " 10/01/2013 - "Patients with SLN+ primary breast cancer were randomized for cALND (arm A, standard treatment) or RNI (arm B, investigational treatment). " 04/01/2010 - "The emerging picture of the biological properties of BCSCs would contribute for devising innovative therapies for breast cancer, targeting the intrinsic and extrinsic factors that maintain the BCSCs."

Related Drugs and Biologics

1.	Praziquantel (Biltricide)
2.	Biological Markers (Surrogate Marker)
3.	MicroRNAs (MicroRNA)
4.	Carbon Monoxide
5.	Dopamine (Intropin)
6.	Artemisinins
7.	Mefloquine (Lariam)
8.	Inosine Pranobex (Imunovir)
9.	artesunate
10.	Interferons

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Transplants (Transplant)
3.	Occupational Therapy (Therapy, Occupational)
4.	Transplantation (Transplant Recipients)
5.	Heterologous Transplantation (Xenotransplantation)