Lamin Type B (Lamin B)

04/01/2000 - "Autoantibodies to human nuclear lamin B1 in systemic lupus erythematosus: comment on the article by Senécal et al."
03/01/1987 - "In addition, autoantibodies to the nuclear lamina in sera of certain patients with systemic lupus erythematosus may be useful for defining the molecular structure and biological functions of lamin B, as well as for studying mechanisms of autoimmunity."
03/01/1987 - "Lamin B autoantibodies in sera of certain patients with systemic lupus erythematosus."
10/01/2002 - "To demonstrate the association between autoantibodies to nuclear lamin B1 (aLB1) and protection against thrombosis ("thromboprotection") in patients with systemic lupus erythematosus (SLE), and to elucidate the mechanism by which aLB1 cause thromboprotection in vivo. "
10/01/2002 - "Association of autoantibodies to nuclear lamin B1 with thromboprotection in systemic lupus erythematosus: lack of evidence for a direct role of lamin B1 in apoptotic blebs."

07/01/1999 - "The presence of LAC without anti-lamin B1 may define a subset of SLE patients at greater risk for thrombosis."
07/01/1999 - "However, patients expressing LAC without anti-lamin B1 had a greater frequency of thrombosis (P = 0.018). "
07/01/1999 - "The frequency of thrombosis in SLE patients expressing both LAC and anti-lamin B1 was similar to that in patients without LAC (P = 1.0). "
07/01/1999 - "Although LAC were significantly associated with thrombosis in our SLE patients, anti-lamin B1 was not. "
10/01/2002 - "To demonstrate the association between autoantibodies to nuclear lamin B1 (aLB1) and protection against thrombosis ("thromboprotection") in patients with systemic lupus erythematosus (SLE), and to elucidate the mechanism by which aLB1 cause thromboprotection in vivo. "

12/01/2020 - "Previous studies have suggested Lamin B2 (LMNB2) as an oncogene in lung cancer. "
01/01/2019 - "We found that lamin B1 levels were reduced in lung cancer patients. "
01/01/2019 - "Here we report that loss of lamin B1, a determinant of nuclear architecture, plays a key role in lung cancer. "
01/01/2020 - "This study aims to investigate the biological effect and molecular mechanism of Lamin B1(LMNB1) in lung cancer cells and its significance for the prognosis of lung adenocarcinoma(LUAD) patients. "
01/01/2023 - "Lamin B1 Overexpresses in Lung Adenocarcinoma and Promotes Proliferation in Lung Cancer Cells via AKT Pathway [Retraction]."

01/01/2022 - "Previous studies have found that lamin B1 (LMNB1) contributes to the development of human cancers. "
10/06/2023 - "Additionally, lamin B1 levels undergo alterations in cancer cells, and a tumor-specific association exists between lamin B1 abundance and cancer aggressiveness. "
01/01/2022 - "We show that loss of nuclear lamin B1 (LMNB1) encoded on chromosome 5q, which is frequently deleted in MNs, induces defects in nuclear morphology and human hematopoietic stem cell (HSC) function associated with malignancy. "
01/01/2022 - "Lamin B1 deletion in myeloid neoplasms causes nuclear anomaly and altered hematopoietic stem cell function."
01/01/2020 - "Moreover, a positive association between lamin B1 levels and tumor formation and progression is found in various cancer types. "

10/19/2019 - "Transfected SRC-3 was SUMOylated and caused redistribution of nuclear promyelocytic leukemia (PML) bodies and perturbation of the nuclear membrane lamin B1, hallmarks of nucleophagy. "
04/10/1998 - "In this report, the p53-null human leukemia HL60 cells were used to investigate phosphorylation and degradation of lamin B during apoptosis. "
04/05/1993 - "Using highly purified human beta II PKC and isolated nuclear envelopes from the human promyelocytic (HL60) leukemia cell line, we have now determined the major sites for beta II PKC-mediated lamin B phosphorylation. "
01/01/2020 - "Individually, lamin B1 highlights acute leukemias, lamin A/C helps distinguish normal from neoplastic mature T cells, and VAMP-7 recapitulates light-cytometric side scatter. "
04/10/1998 - "Lamin B phosphorylation by protein kinase calpha and proteolysis during apoptosis in human leukemia HL60 cells."