Mitochondrial Membrane Transport Proteins (Membrane Transport Proteins, Mitochondrial)

Proteins involved in the transport of specific substances across the membranes of the MITOCHONDRIA.

Also Known As:

Membrane Transport Proteins, Mitochondrial; Carrier Proteins, Mitochondrial; Transport Proteins, Mitochondrial; Mitochondrial Carrier Proteins; Mitochondrial Carriers; Mitochondrial Transport Proteins

Networked: 10 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Membrane Transport Proteins: 589
      - Mitochondrial Membrane Transport Proteins: 10
        Mitochondrial Permeability Transition Pore: 807
        Mitochondrial Uncoupling Proteins: 397
        ATP Translocases Mitochondrial ADP: 132
        Mitochondrial Proton-Translocating ATPases: 113
        Voltage-Dependent Anion Channel 1: 79
        Mitochondrial Precursor Protein Import Complex Proteins: 17
        Member 2 Protein Solute Carrier Family 44: 11
        Voltage-Dependent Anion Channel 2: 8
        Anopheles gambiae mitochondrial carrier 1 protein: 1
        human SLC25A33 protein: 1
        Arabidopsis ADNT1 protein
        Arabidopsis At4g05590 protein
        Arabidopsis AT4G22310 protein
        Arabidopsis B14.7 protein
        Arabidopsis Mic60 protein
        Arabidopsis Om64 protein
        Arabidopsis solute carrier family 25 member 17 protein
        Arabidopsis Tom20 protein
        Arabidopsis Tom40 protein
        C elegans Mcu-1 protein
        C elegans mtx-1 protein
        C elegans mtx-2 protein
        Drosophila COLT protein
        Drosophila EMRE protein
        Drosophila GC1 protein
        Drosophila GC2 protein
        Drosophila MICU1 protein
        Drosophila MICU3 protein
        Drosophila shawn protein
        human DNAJC19 protein
        human Mfn1 protein
        human MICU1 protein
        human MMAA protein
        human MPC1 protein
        human MPC2 protein
        human MTCH2 protein
        human MTX1 protein
        human RTL10 protein
        human SLC25A12 protein
        human SLC25A13 protein
        human SLC25A15 protein
        human SLC25A19 protein
        human SLC25A21 protein
        human SLC25A22 protein
        human SLC25A25 protein
        human SLC25A36 protein
        human Slc25a38 protein
        human SLC25A39 protein
        human SLC25A40 protein
        human SLC25A48 protein
        human SLC25A51 protein
        human Tom40 protein
        human VDAC3 protein
        mouse HDMCP protein
        mouse MICU1 protein
        mouse Micu3 protein
        mouse MPC1 pyruvate carrier protein
        mouse MPC2 pyruvate carrier protein
        mouse Mscp protein
        mouse Mtch2 protein
        mouse Mtx1 protein
        mouse SCaMC-1like protein
        mouse Slc25a12 protein
        mouse Slc25a13 protein
        mouse Slc25a15 protein
        mouse Slc25a19 protein
        mouse Slc25a21 protein
        mouse Slc25a22 protein
        mouse Slc25a25 protein
        mouse Slc25a36 protein
        mouse Slc25a38 protein
        mouse Slc25a39 protein
        mouse Slc25a51 protein
        mouse TMEM14C protein
        mouse Tom22 protein
        mouse Vdac3 protein
        rat MICU1 protein
        rat Micu3 protein
        rat MTCH2 protein
        rat Sfxn5 protein
        rat Slc25a12 protein
        rat Slc25a25 protein
        rat Slc25a47 protein
        rat Slc8b1 protein
        rat Vdac3 protein
        S cerevisiae FMP43 protein
        S cerevisiae MGE1 protein
        S cerevisiae Mgr1 protein
        S cerevisiae OM14 protein
        S cerevisiae ORT1 protein
        S cerevisiae TIM54 protein
        S cerevisiae TOM20 protein
        S cerevisiae TOM22 protein
        S cerevisiae Tom40 protein
        S cerevisiae TOM71 protein
        S cerevisiae YMC1 protein
        zebrafish slc25a46 protein
  - Mitochondrial Proteins: 1823
    - Mitochondrial Membrane Transport Proteins: 10

Experts

1.	Bayat, Gholamreza: 1 article (01/2022)
2.	Bayat, Mahnaz: 1 article (01/2022)
3.	Fallah, Parviz: 1 article (01/2022)
4.	Hashemi, Seyed Ali: 1 article (01/2022)
5.	Hedayatyanfard, Keshvad: 1 article (01/2022)
6.	Karim, Hosein: 1 article (01/2022)
7.	Khalili, Azadeh: 1 article (01/2022)
8.	Gao, Li: 1 article (01/2021)
9.	Gou, Na: 1 article (01/2021)
10.	Liao, Linfeng: 1 article (01/2021)

Related Diseases

1.	Mitochondrial Diseases (Mitochondrial Disease) 01/01/2021 - "To more comprehensively explore the complex relationship between aging and mitochondria dysfunction, we have developed a mouse model with Slc25a46 knockout, a nuclear gene described as encoding mitochondrial carriers, by CRISPR/Cas9 gene editing to mimic some typical aging phenotypes in human. " 10/01/2023 - "Mitochondrial dysfunction causes oxidative stress, triggering hepatocyte death and inflammation; therefore, the present study aimed to explore relationship between mitochondrial carriers and oxidative stress. " 02/10/2016 - "Our work provides the first functional annotation of these essential mitochondrial carriers in the nervous system, and the results suggest that metal imbalances and mitochondrial dysfunction may contribute to defects in synaptic transmission and neuronal survival. "
2.	Inflammation (Inflammations) 01/01/2017 - "This review summarises the mitochondrial carriers studied so far that are, directly or indirectly, involved in inflammation." 10/01/2023 - "Mitochondrial dysfunction causes oxidative stress, triggering hepatocyte death and inflammation; therefore, the present study aimed to explore relationship between mitochondrial carriers and oxidative stress. " 01/01/2017 - "In this context, mitochondrial carriers, which catalyse the transport of solute across mitochondrial membrane, change their expression to transport mitochondrially produced molecules, among which citrate and succinate, to be used as intracellular signalling molecules in inflammation. " 01/01/2017 - "Mitochondrial carriers in inflammation induced by bacterial endotoxin and cytokines."
3.	Fibrosis (Cirrhosis) 01/01/2022 - "This study aimed to evaluate the relationship between Farnesoid-X-activated receptors (FXR) as nuclear regulators of the antioxidant defense system as well as cardiac mitochondrial carrier proteins of UCP2 and UCP3 in cardiac damage induced by cirrhosis. "
4.	Starvation 10/13/2016 - "However, TRAK1, TRAK2 and Milton (which have a "Milt/TRAK" domain that is absent in human and rodent HAP1) differ in function to HAP1 in that they are mitochondrial transport proteins, while HAP1 has emerging roles in starvation response. "
5.	Neoplasms (Cancer) 08/01/2017 - "Expression and putative role of mitochondrial transport proteins in cancer."

Related Drugs and Biologics

1.	Antioxidants
2.	farnesoid X-activated receptor
3.	Succinic Acid (Succinate)
4.	Citric Acid (Citrate)
5.	Cytokines
6.	Metals
7.	Endotoxins