Poult Enteritis Mortality Syndrome

An acute, transmissible, infectious disease associated with high MORTALITY and MORBIDITY in young turkeys (poults). It is characterized by DIARRHEA; ANOREXIA; growth depression, and immune dysfunction. The cause is unknown but astroviruses (AVASTROVIRUS) and coronaviruses (CORONAVIRUS, TURKEY) have been isolated from diseased poults and are thought to cause the enteritis and increased susceptibility to bacterial infections.

Also Known As:

Networked: 20 relevant articles (0 outcomes, 2 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Enteritis
2.	Growth Disorders
3.	Hypoglycemia (Reactive Hypoglycemia)
4.	Communicable Diseases (Infectious Diseases)
5.	Body Weight (Weight, Body)

Experts

1.	Barnes, H J: 3 articles (04/2002 - 04/2000)
2.	Guy, J S: 3 articles (04/2002 - 05/2000)
3.	Strother, K O: 2 articles (02/2011 - 08/2008)
4.	Zsak, L: 2 articles (02/2011 - 08/2008)
5.	Vaillancourt, J P: 2 articles (04/2002 - 10/2001)
6.	Koci, M D: 2 articles (01/2001 - 04/2000)
7.	Schultz-Cherry, S: 2 articles (01/2001 - 04/2000)
8.	Buyse, J: 1 article (10/2020)
9.	Everaert, N: 1 article (10/2020)
10.	Lamberigts, C: 1 article (10/2020)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Poult Enteritis Mortality Syndrome:

1.	Blood Glucose (Blood Sugar)IBA 04/01/1995 - "The purposes of this study were to 1) measure blood glucose values in a flock of broiler chicks tentatively diagnosed as having spiking mortality syndrome (SMS), and 2) compare the blood glucose values using two methods: the Chemstrip bG visual method and the Chemstrip bG Accu-Chek III monitor method. " 07/25/2020 - "Notably, hypoglycemia is often associated with Spiking Mortality Syndrome in broilers; therefore, blood glucose levels need to be correctly evaluated in clinical diagnosis. " 04/01/1995 - "Pancreata from 19 hypoglycemic field broilers with spiking mortality syndrome and 19 clinically normal field broilers with normal blood glucose levels were collected and quick-frozen in liquid nitrogen immediately after the chicks were bled and killed. "
2.	2-(4-fluorophenyl)-N-methylsuccinimideIBA 09/01/1995 - "The purpose of the present study was to use clinical epidemiologic tools to define the relationship between production performance data, virus particles, and intestinal fringed membranous particles (FMPs) in healthy turkey poults and in poults that were experiencing an outbreak of poult enteritis complex (PEC) and spiking mortality syndrome (SMS). "
3.	3-(2-phenylethyl)-4-methylsydnoneIBA 10/01/2002 - "Poult enteritis mortality syndrome (PEMS) has been an economically devastating disease in North Carolina since the early 1990s. " 04/01/2002 - "Enteropathogenic Escherichia coli (EPEC) previously were identified in poult enteritis-mortality syndrome (PEMS)-affected turkeys and associated as a cause of this disease. " 10/01/2001 - "Poult enteritis mortality syndrome (PEMS) is an economically devastating disease. " 01/01/2001 - "Outbreaks of poult enteritis mortality syndrome (PEMS) continue to cause financial losses to the turkey industry. " 05/01/2000 - "Turkey coronavirus (TCV) from two sources was studied, one isolate (NC95) was embryo propagated, the second was TCV infected material from turkeys diagnosed with poult enteritis mortality syndrome (PEMS). "
4.	Hypoglycemic Agents (Hypoglycemics)IBA 04/01/1997 - "Six chicks (40%) developed clinical signs of spiking mortality syndrome and were severely hypoglycemic. " 01/01/1995 - "Inocula produced from field broilers with spiking mortality syndrome contained the highest numbers of the arena-virus-like particles and produced the highest percentage of hypoglycemic chicks 13-15 days postinoculation after a 5-to-9-hour fast. " 04/01/1995 - "Pancreata from 19 hypoglycemic field broilers with spiking mortality syndrome and 19 clinically normal field broilers with normal blood glucose levels were collected and quick-frozen in liquid nitrogen immediately after the chicks were bled and killed. "
5.	Glucose (Dextrose)FDA LinkGeneric 04/01/1997 - "However, plasma glucose levels in the affected poults were within the normal range, unlike chickens with spiking mortality syndrome. " 10/01/2020 - "Spiking mortality syndrome was induced successfully with the treatments, according to their significantly reduced plasma glucose, insulin, T3 and T4 concentrations as well as liver glycogen content. "
6.	Drinking WaterIBA 05/01/2004 - "The objectives of this paper were 1) to simulate the inanition of poult enteritis mortality syndrome by restricting feed intake and 2) to develop a drinking water supplement that supports the immune functions of poults with inanition. "
7.	Uric Acid (Urate)IBA 01/01/1995 - "Seven groups of day-old male primary broiler breeder chicks were orally inoculated with tissue and/or fecal-urate homogenates taken from field broilers with spiking mortality syndrome and from field broilers with enteritis and/or runting-stunting syndrome. "
8.	Growth Hormone (Somatotropin)IBA 04/01/1997 - "Twelve days postinoculation, the mean plasma insulinlike growth factor-1 (IGF-1) level and mean body weights were significantly depressed, and the mean plasma growth hormone level was significantly elevated, in the poults receiving the turkey-derived homogenate (P < or = 0.0003), as was previously reported in chickens with spiking mortality syndrome. "
9.	NitrogenIBA 04/01/1995 - "Pancreata from 19 hypoglycemic field broilers with spiking mortality syndrome and 19 clinically normal field broilers with normal blood glucose levels were collected and quick-frozen in liquid nitrogen immediately after the chicks were bled and killed. "
10.	Liver GlycogenIBA 10/01/2020 - "Spiking mortality syndrome was induced successfully with the treatments, according to their significantly reduced plasma glucose, insulin, T3 and T4 concentrations as well as liver glycogen content. "